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The modeling of time-to-event data, also known as survival analysis, requires specialized methods that can deal with censoring and truncation, time-varying features and effects, and that extend to settings with multiple competing events.…

Machine Learning · Statistics 2021-04-20 Andreas Bender , David Rügamer , Fabian Scheipl , Bernd Bischl

We consider the problem of estimating the distribution of time-to-event data that are subject to censoring and for which the event of interest might never occur, i.e., some subjects are cured. To model this kind of data in the presence of…

Statistics Theory · Mathematics 2018-06-05 François Portier , Ingrid Van Keilegom , Anouar El Ghouch

Estimating the effects of interventions on patient outcome is one of the key aspects of personalized medicine. Their inference is often challenged by the fact that the training data comprises only the outcome for the administered treatment,…

Epidemiological evidence is based on multiple data sources including clinical trials, cohort studies, surveys, registries and expert opinions. Merging information from different sources opens up new possibilities for the estimation of…

Applications · Statistics 2024-07-03 Juha Karvanen , Santtu Tikka , Antti Hyttinen

Survival Analysis (SA) constitutes the default method for time-to-event modeling due to its ability to estimate event probabilities of sparsely occurring events over time. In this work, we show how to improve the training and inference of…

Machine Learning · Computer Science 2023-12-12 Chris Solomou

Federated learning of causal estimands may greatly improve estimation efficiency by leveraging data from multiple study sites, but robustness to heterogeneity and model misspecifications is vital for ensuring validity. We develop a…

Methodology · Statistics 2023-10-06 Larry Han , Jue Hou , Kelly Cho , Rui Duan , Tianxi Cai

Causal inference has received great attention across different fields from economics, statistics, education, medicine, to machine learning. Within this area, inferring causal effects at individual level in observational studies has become…

Methodology · Statistics 2017-02-16 Thai Pham

Survival analysis, or time-to-event modelling, is a classical statistical problem that has garnered a lot of interest for its practical use in epidemiology, demographics or actuarial sciences. Recent advances on the subject from the point…

Machine Learning · Computer Science 2021-07-28 Guillaume Ausset , Tom Ciffreo , Francois Portier , Stephan Clémençon , Timothée Papin

Synthetic data is becoming an increasingly promising technology, and successful applications can improve privacy, fairness, and data democratization. While there are many methods for generating synthetic tabular data, the task remains…

Machine Learning · Computer Science 2023-02-27 Alexander Norcliffe , Bogdan Cebere , Fergus Imrie , Pietro Lio , Mihaela van der Schaar

We propose a new framework for binary classification in transfer learning settings where both covariate and label distributions may shift between source and target domains. Unlike traditional covariate shift or label shift assumptions, we…

Methodology · Statistics 2025-09-29 Manli Cheng , Subha Maity , Qinglong Tian , Pengfei Li

We introduce a new predictive mechanism that operates in the presence of hidden confounding across distributionally diverse data sources while ensuring consistent estimation of causal parameters-despite their recognized suboptimality for…

Statistics Theory · Mathematics 2025-04-01 Carlos García Meixide , David Ríos Insua

Recently, \textit{diffusion history inference} has become an emerging research topic due to its great benefits for various applications, whose purpose is to reconstruct the missing histories of information diffusion traces according to…

Social and Information Networks · Computer Science 2017-08-24 Yanchao Sun , Cong Qian , Ning Yang , Philip S. Yu

Causal inference is central to statistics and scientific discovery, enabling researchers to identify cause-and-effect relationships beyond associations. While traditionally studied within Euclidean spaces, contemporary applications…

Methodology · Statistics 2025-07-01 Satarupa Bhattacharjee , Bing Li , Xiao Wu , Lingzhou Xue

Weighting methods are essential tools for estimating causal effects in observational studies, with the goal of balancing pre-treatment covariates across treatment groups. Traditional approaches pursue this objective indirectly, for example,…

Methodology · Statistics 2026-02-09 Diptanil Santra , Guanhua Chen , Chan Park

Recent advances in causal mediation analysis have formalized conditions for estimating direct and indirect effects in various contexts. These approaches have been extended to a number of models for survival outcomes including accelerated…

Methodology · Statistics 2017-01-11 Isabel R. Fulcher , Eric Tchetgen Tchetgen , Paige L. Williams

We present a neural network framework for learning a survival model to predict a time-to-event outcome while simultaneously learning a topic model that reveals feature relationships. In particular, we model each subject as a distribution…

Machine Learning · Computer Science 2024-06-06 George H. Chen , Linhong Li , Ren Zuo , Amanda Coston , Jeremy C. Weiss

Reliable estimation of spatio-temporal trends in population-level HIV incidence is becoming an increasingly critical component of HIV prevention policy-making. However, direct measurement is nearly impossible. Current, widely used models…

Applications · Statistics 2019-12-04 Timothy M Wolock , Seth R Flaxman , Jeffrey W Eaton

Causal inference is made challenging by confounding, selection bias, and other complications. A common approach to addressing these difficulties is the inclusion of auxiliary data on the superpopulation of interest. Such data may measure a…

Methodology · Statistics 2024-04-16 Jaron J. R. Lee , AmirEmad Ghassami , Ilya Shpitser

Generalization methods offer a powerful solution to one of the key drawbacks of randomized controlled trials (RCTs): their limited representativeness. By enabling the transport of treatment effect estimates to target populations subject to…

Methodology · Statistics 2025-05-20 Ahmed Boughdiri , Clément Berenfeld , Julie Josse , Erwan Scornet

Randomized experiments have become a cornerstone of evidence-based decision-making in contexts ranging from online platforms to public health. However, in experimental settings with network interference, a unit's treatment can influence…

Machine Learning · Computer Science 2025-10-22 Sadegh Shirani , Yuwei Luo , William Overman , Ruoxuan Xiong , Mohsen Bayati