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We use Topological Data Analysis tools for studying the inner organization of cells in segmented images of epithelial tissues. More specifically, for each segmented image, we compute different persistence barcodes, which codify lifetime of…

Computer Vision and Pattern Recognition · Computer Science 2022-04-11 N. Atienza , M. J. Jimenez , M. Soriano-Trigueros

Artificial intelligence (AI) techniques have been proposed for automating analysis of short axis (SAX) cine cardiac magnetic resonance (CMR), but no CMR analysis tool exists to automatically analyse large (unstructured) clinical CMR…

Causal reasoning provides a language to ask important interventional and counterfactual questions beyond purely statistical association. In medical imaging, for example, we may want to study the causal effect of genetic, environmental, or…

Computer Vision and Pattern Recognition · Computer Science 2022-08-24 Rajat Rasal , Daniel C. Castro , Nick Pawlowski , Ben Glocker

The application of single-cell molecular profiling coupled with spatial technologies has enabled charting cellular heterogeneity in reference tissues and in disease. This new wave of molecular data has highlighted the expected diversity of…

Tissues and Organs · Quantitative Biology 2024-03-12 Ricardo Omar Ramirez Flores , Philipp Sven Lars Schäfer , Leonie Küchenhoff , Julio Saez-Rodriguez

In this work, we developed new mathematical methods for analyzing network topology and applied these methods to the analysis of brain networks. More specifically, we rigorously developed quantitative methods based on complexes constructed…

Neurons and Cognition · Quantitative Biology 2026-04-28 Heitor Baldo

Echocardiography is an essential medical technique for diagnosing cardiovascular diseases, but its high operational complexity has led to a shortage of trained professionals. To address this issue, we introduce a novel probe movement…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Haojun Jiang , Teng Wang , Zhenguo Sun , Yulin Wang , Yang Yue , Yu Sun , Ning Jia , Meng Li , Shaqi Luo , Shiji Song , Gao Huang

Cardiac arrhythmia is a prevalent and significant cause of morbidity and mortality among cardiac ailments. Early diagnosis is crucial in providing intervention for patients suffering from cardiac arrhythmia. Traditionally, diagnosis is…

Signal Processing · Electrical Eng. & Systems 2020-04-14 Sricharan Vijayarangan , Balamurali Murugesan , Vignesh R , Preejith SP , Jayaraj Joseph , Mohansankar Sivaprakasam

Cardiac cine magnetic resonance imaging (MRI) has been used to characterize cardiovascular diseases (CVD), often providing a noninvasive phenotyping tool.~While recently flourished deep learning based approaches using cine MRI yield…

Image and Video Processing · Electrical Eng. & Systems 2023-01-24 Xiaofeng Liu , Fangxu Xing , Hanna K. Gaggin , C. -C. Jay Kuo , Georges El Fakhri , Jonghye Woo

Functional and structural connectivity (FC/SC) are key multimodal biomarkers for brain analysis, yet their clinical utility is hindered by costly acquisition, complex preprocessing, and frequent missing modalities. Existing foundation…

Neurons and Cognition · Quantitative Biology 2025-11-11 Xiongri Shen , Jiaqi Wang , Yi Zhong , Zhenxi Song , Leilei Zhao , Liling Li , Yichen Wei , Lingyan Liang , Shuqiang Wang , Baiying Lei , Demao Deng , Zhiguo Zhang

Improving the precision of heart diseases detection has been investigated by many researchers in the literature. Such improvement induced by the overwhelming health care expenditures and erroneous diagnosis. As a result, various…

Computers and Society · Computer Science 2018-03-29 Israa Ahmed Zriqat , Ahmad Mousa Altamimi , Mohammad Azzeh

The morphological structure of left ventricle segmented from cardiac magnetic resonance images can be used to calculate key clinical parameters, and it is of great significance to the accurate and efficient diagnosis of cardiovascular…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Han Kang , Defeng Chen

The medical field is creating large amount of data that physicians are unable to decipher and use efficiently. Moreover, rule-based expert systems are inefficient in solving complicated medical tasks or for creating insights using big data.…

Computer Vision and Pattern Recognition · Computer Science 2024-04-05 Paschalis Bizopoulos , Dimitrios Koutsouris

Automated segmentation of Cardiac Magnetic Resonance (CMR) plays a pivotal role in efficiently assessing cardiac function, offering rapid clinical evaluations that benefit both healthcare practitioners and patients. While recent research…

Image and Video Processing · Electrical Eng. & Systems 2024-06-14 Abdul Qayyum , Hao Xu , Brian P. Halliday , Cristobal Rodero , Christopher W. Lanyon , Richard D. Wilkinson , Steven Alexander Niederer

Human anatomy is the foundation of medical imaging and boasts one striking characteristic: its hierarchy in nature, exhibiting two intrinsic properties: (1) locality: each anatomical structure is morphologically distinct from the others;…

Computer Vision and Pattern Recognition · Computer Science 2023-09-28 Mohammad Reza Hosseinzadeh Taher , Michael B. Gotway , Jianming Liang

Machine learning methods provide a methodological innovation that can help screen for cardiovascular disease through noninvasive and readily available measurement modalities. Recent investments in using electrocardiogram (ECG) data to…

Quantitative Methods · Quantitative Biology 2026-05-25 Mitchel J. Colebank

Challenges such as the lack of high-quality annotations, long-tailed data distributions, and inconsistent staining styles pose significant obstacles to training neural networks to detect abnormal cells in cytopathology robustly. This paper…

Computer Vision and Pattern Recognition · Computer Science 2025-06-27 Qiuyi Qi , Xin Li , Ming Kong , Zikang Xu , Bingdi Chen , Qiang Zhu , S Kevin Zhou

Automatic detection and classification of Cardiovascular disease (CVD) from Computed Tomography (CT) images play an important part in facilitating better-informed clinical decisions. However, most of the recent deep learning based methods…

Image and Video Processing · Electrical Eng. & Systems 2026-05-07 Ajay Mittal , Raghav Mehta , Omar Todd , Philipp Seeböck , Georg Langs , Ben Glocker

Delineation of the cardiac structures from 2D echocardiographic images is a common clinical task to establish a diagnosis. Over the past decades, the automation of this task has been the subject of intense research. In this paper, we…

Assessment of cardiovascular disease (CVD) with cine magnetic resonance imaging (MRI) has been used to non-invasively evaluate detailed cardiac structure and function. Accurate segmentation of cardiac structures from cine MRI is a crucial…

Image and Video Processing · Electrical Eng. & Systems 2021-07-23 Xiaofeng Liu , Fangxu Xing , Hanna K. Gaggin , Weichung Wang , C. -C. Jay Kuo , Georges El Fakhri , Jonghye Woo

Deep learning has the potential to automate echocardiogram analysis for early detection of heart disease. Based on a qualitative analysis of design concerns, this study suggests that predicting normal heart function instead of disease…

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