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With the advent of sophisticated machine learning (ML) techniques and the promising results they yield, especially in medical applications, where they have been investigated for different tasks to enhance the decision-making process. Since…

Neural networks are ubiquitous in applied machine learning for education. Their pervasive success in predictive performance comes alongside a severe weakness, the lack of explainability of their decisions, especially relevant in…

Machine Learning · Computer Science 2022-07-04 Vinitra Swamy , Bahar Radmehr , Natasa Krco , Mirko Marras , Tanja Käser

Any supervised machine learning analysis is required to provide an estimate of the out-of-sample predictive performance. However, it is imperative to also provide a quantification of the uncertainty of this performance in the form of a…

Machine Learning · Computer Science 2024-06-13 Konstantinos Paraschakis , Andrea Castellani , Giorgos Borboudakis , Ioannis Tsamardinos

In a world where Machine Learning (ML) is increasingly deployed to support decision-making in critical domains, providing decision-makers with explainable, stable, and relevant inputs becomes fundamental. Understanding how machine learning…

Machine Learning · Computer Science 2024-08-07 Karol Capała , Paulina Tworek , Jose Sousa

The adoption of machine learning (ML) and, more specifically, deep learning (DL) applications into all major areas of our lives is underway. The development of trustworthy AI is especially important in medicine due to the large implications…

Machine Learning · Computer Science 2024-02-22 Daniel Schwabe , Katinka Becker , Martin Seyferth , Andreas Klaß , Tobias Schäffter

The main question is: why and how can we ever predict based on a finite sample? The question is not answered by statistical learning theory. Here, I suggest that prediction requires belief in "predictability" of the underlying dependence,…

Machine Learning · Computer Science 2022-01-28 Marina Sapir

Text-based explainable recommendation aims to generate natural-language explanations that justify item recommendations, to improve user trust and system transparency. Although recent advances leverage LLMs to produce fluent outputs, a…

Information Retrieval · Computer Science 2026-05-18 Ben Kabongo , Vincent Guigue

Large language models (LLMs) show promise for clinical use. They are often evaluated using datasets such as MedQA. However, Many medical datasets, such as MedQA, rely on simplified Question-Answering (Q\A) that underrepresents real-world…

Computation and Language · Computer Science 2025-10-24 Yunpeng Xiao , Carl Yang , Mark Mai , Xiao Hu , Kai Shu

Machine learning (ML) in medicine has transitioned from research to concrete applications aimed at supporting several medical purposes like therapy selection, monitoring and treatment. Acceptance and effective adoption by clinicians and…

Integrating language models (LMs) in healthcare systems holds great promise for improving medical workflows and decision-making. However, a critical barrier to their real-world adoption is the lack of reliable evaluation of their…

Computation and Language · Computer Science 2025-12-15 Akash Ghosh , Srivarshinee Sridhar , Raghav Kaushik Ravi , Muhsin Muhsin , Sriparna Saha , Chirag Agarwal

There is a strong consensus that combining the versatility of machine learning with the assurances given by formal verification is highly desirable. It is much less clear what verified machine learning should mean exactly. We consider this…

Machine Learning · Computer Science 2021-02-15 Tonicha Crook , Jay Morgan , Arno Pauly , Markus Roggenbach

Machine learning (ML) promises better clinical decision-making, yet opaque model behavior limits the adoption in healthcare. We propose two novel regularization techniques for ensuring the interpretability of ML models trained on real-world…

Machine Learning · Computer Science 2026-03-24 Salma Rachidi , Aso Bozorgpanah , Eric Fey , Alexander Jung

Large Language Models (LLMs) have shown significant advances in text generation but often lack the reliability needed for autonomous deployment in high-stakes domains like healthcare, law, and finance. Existing approaches rely on external…

Artificial Intelligence · Computer Science 2024-11-12 Ninad Naik

Selective inference aims at providing valid inference after a data-driven selection of models or hypotheses. It is essential to avoid overconfident results and replicability issues. While significant advances have been made in this area for…

Methodology · Statistics 2025-03-14 Matteo D'Alessandro , Magne Thoresen

Explainable machine learning (ML) enables human learning from ML, human appeal of automated model decisions, regulatory compliance, and security audits of ML models. Explainable ML (i.e. explainable artificial intelligence or XAI) has been…

Machine Learning · Statistics 2019-12-03 Patrick Hall , Navdeep Gill , Nicholas Schmidt

Following the recent surge in adoption of machine learning (ML), the negative impact that improper use of ML can have on users and society is now also widely recognised. To address this issue, policy makers and other stakeholders, such as…

Software Engineering · Computer Science 2021-03-02 Alex Serban , Koen van der Blom , Holger Hoos , Joost Visser

In the last few decades, Machine Learning (ML) has achieved significant success across domains ranging from healthcare, sustainability, and the social sciences, to criminal justice and finance. But its deployment in increasingly…

Machine Learning · Computer Science 2025-09-03 Nathan Justin , Qingshi Sun , Andrés Gómez , Phebe Vayanos

The potential of Multimodal Large Language Models (MLLMs) in domain of medical imaging raise the demands of systematic and rigorous evaluation frameworks that are aligned with the real-world medical imaging practice. Existing practices that…

Computation and Language · Computer Science 2026-04-16 Zhijie Bao , Fangke Chen , Licheng Bao , Chenhui Zhang , Wei Chen , Jiajie Peng , Zhongyu Wei

Accurate and reliable diagnosis of diseases is crucial in enabling timely medical treatment and enhancing patient survival rates. In recent years, Machine Learning has revolutionized diagnostic practices by creating classification models…

Machine Learning · Computer Science 2025-12-02 Antonio Tudisco , Deborah Volpe , Giovanna Turvani

With the advent of Deep Learning, the field of machine learning (ML) has surpassed human-level performance on diverse classification tasks. At the same time, there is a stark need to characterize and quantify reliability of a model's…

Machine Learning · Computer Science 2021-11-16 Nurali Virani , Naresh Iyer , Zhaoyuan Yang
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