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Object segmentation and structure localization are important steps in automated image analysis pipelines for microscopy images. We present a convolution neural network (CNN) based deep learning architecture for segmentation of objects in…

Computer Vision and Pattern Recognition · Computer Science 2019-01-24 Shan E Ahmed Raza , Linda Cheung , Muhammad Shaban , Simon Graham , David Epstein , Stella Pelengaris , Michael Khan , Nasir M. Rajpoot

The fast growing deep learning technologies have become the main solution of many machine learning problems for medical image analysis. Deep convolution neural networks (CNNs), as one of the most important branch of the deep learning…

Computer Vision and Pattern Recognition · Computer Science 2017-08-25 Zizhao Zhang , Fuyong Xing , Hai Su , Xiaoshuang Shi , Lin Yang

Ultrasound denoising is essential for mitigating speckle-induced degradations, thereby enhancing image quality and improving diagnostic reliability. Nevertheless, because speckle patterns inherently encode both texture and fine anatomical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Zhenyu Bu , Yuanxin Xie , Guang-Quan Zhou

Ultrasound contrast imaging is a specialized imaging technique that applies microbubble contrast agents to traditional medical sonography, providing real-time visualization of blood flow and vessels. Gas-filled microbubbles are injected…

Analysis of PDEs · Mathematics 2024-12-17 Vanja Nikolić , Teresa Rauscher

Thanks to its capability of acquiring full-view frames at multiple kilohertz, ultrafast ultrasound imaging unlocked the analysis of rapidly changing physical phenomena in the human body, with pioneering applications such as ultrasensitive…

Image and Video Processing · Electrical Eng. & Systems 2020-12-22 Dimitris Perdios , Manuel Vonlanthen , Florian Martinez , Marcel Arditi , Jean-Philippe Thiran

Imaging the human brain vasculature with high spatial and temporal resolution remains challenging in the clinic today. Transcranial ultrasound is scarcely used for cerebrovascular imaging, due to low sensitivity and strong phase aberrations…

Perfusion by the microcirculation is key to the development, maintenance and pathology of tissue. Its measurement with high spatiotemporal resolution is consequently valuable but remains a challenge in deep tissue. Ultrasound Localization…

Signal Processing · Electrical Eng. & Systems 2023-04-26 Kai Riemer , Matthieu Toulemonde , Jipeng Yan , Marcelo Lerendegui , Eleanor Stride , Peter D. Weinberg , Christopher Dunsby , Meng-Xing Tang

Flow-Imaging Microscopy (FIM) is commonly used in both academia and industry to characterize subvisible particles (those $\le 25 \mu m$ in size) in protein therapeutics. Pharmaceutical companies are required to record vast volumes of FIM…

Quantitative Methods · Quantitative Biology 2017-09-04 Christopher P. Calderon , Austin L. Daniels , Theodore W. Randolph

The anatomical location of imaging features is of crucial importance for accurate diagnosis in many medical tasks. Convolutional neural networks (CNN) have had huge successes in computer vision, but they lack the natural ability to…

Computer Vision and Pattern Recognition · Computer Science 2016-11-01 Mohsen Ghafoorian , Nico Karssemeijer , Tom Heskes , Inge van Uden , Clara Sanchez , Geert Litjens , Frank-Erik de Leeuw , Bram van Ginneken , Elena Marchiori , Bram Platel

In this survey paper, we review recent uses of convolution neural networks (CNNs) to solve inverse problems in imaging. It has recently become feasible to train deep CNNs on large databases of images, and they have shown outstanding…

Image and Video Processing · Electrical Eng. & Systems 2018-09-11 Michael T. McCann , Kyong Hwan Jin , Michael Unser

Convolution is a central operation in Convolutional Neural Networks (CNNs), which applies a kernel to overlapping regions shifted across the image. However, because of the strong correlations in real-world image data, convolutional kernels…

Inverse problems in image and audio, and super-resolution in particular, can be seen as high-dimensional structured prediction problems, where the goal is to characterize the conditional distribution of a high-resolution output given its…

Computer Vision and Pattern Recognition · Computer Science 2016-03-02 Joan Bruna , Pablo Sprechmann , Yann LeCun

Automatic learning algorithms for improving the image quality of diagnostic B-mode ultrasound (US) images have been gaining popularity in the recent past. In this work, a novel convolutional neural network (CNN) is trained using time of…

Signal Processing · Electrical Eng. & Systems 2021-08-18 Roshan P Mathews , Mahesh Raveendranatha Panicker

Deep learning algorithms offer a powerful means to automatically analyze the content of medical images. However, many biological samples of interest are primarily transparent to visible light and contain features that are difficult to…

Computer Vision and Pattern Recognition · Computer Science 2017-09-22 Roarke Horstmeyer , Richard Y. Chen , Barbara Kappes , Benjamin Judkewitz

In Ultrasound Localization Microscopy (ULM), achieving high-resolution images relies on the precise localization of contrast agent particles across a series of beamformed frames. However, our study uncovers an enormous potential: The…

Computational Geometry · Computer Science 2024-04-09 Christopher Hahne , Georges Chabouh , Arthur Chavignon , Olivier Couture , Raphael Sznitman

The purpose of this study is to enable in-vivo three-dimensional (3-D) ultrasound localization microscopy (ULM) of posterior ocular microvasculature using a 256-channel system and a 1024-element matrix array, and to overcome limitations of…

An automated and reliable processing of bubbly flow images is highly needed to analyse large data sets of comprehensive experimental series. A particular difficulty arises due to overlapping bubble projections in recorded images, which…

Computer Vision and Pattern Recognition · Computer Science 2022-08-08 Hendrik Hessenkemper , Sebastian Starke , Yazan Atassi , Thomas Ziegenhein , Dirk Lucas

We report the development of deep learning coherent electron diffractive imaging at sub-angstrom resolution using convolutional neural networks (CNNs) trained with only simulated data. We experimentally demonstrate this method by applying…

Materials Science · Physics 2022-04-19 Dillan J. Chang , Colum M. O'Leary , Cong Su , Salman Kahn , Alex Zettl , Jim Ciston , Peter Ercius , Jianwei Miao

Existing video super-resolution (SR) algorithms usually assume that the blur kernels in the degradation process are known and do not model the blur kernels in the restoration. However, this assumption does not hold for video SR and usually…

Computer Vision and Pattern Recognition · Computer Science 2020-03-11 Jinshan Pan , Songsheng Cheng , Jiawei Zhang , Jinhui Tang

PURPOSE: Real-time assessment of ventricular volumes requires high acceleration factors. Residual convolutional neural networks (CNN) have shown potential for removing artifacts caused by data undersampling. In this study we investigated…

Computer Vision and Pattern Recognition · Computer Science 2020-09-07 Andreas Hauptmann , Simon Arridge , Felix Lucka , Vivek Muthurangu , Jennifer A. Steeden