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Cardiac magnetic resonance imaging (CMR) offers detailed evaluation of cardiac structure and function, but its limited accessibility restricts use to selected patient populations. In contrast, the electrocardiogram (ECG) is ubiquitous and…

In this paper, we consider the problem of disease diagnosis. Unlike the conventional learning paradigm that treats labels independently, we propose a knowledge-enhanced framework, that enables training visual representation with the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-28 Chaoyi Wu , Xiaoman Zhang , Yanfeng Wang , Ya Zhang , Weidi Xie

Recently, contrastive learning (CL) plays an important role in exploring complementary information for multi-view clustering (MVC) and has attracted increasing attention. Nevertheless, real-world multi-view data suffer from data…

Machine Learning · Computer Science 2025-12-29 Hongqing He , Jie Xu , Wenyuan Yang , Yonghua Zhu , Guoqiu Wen , Xiaofeng Zhu

Contrastive language-image Pre-training (CLIP) [13] can leverage large datasets of unlabeled Image-Text pairs, which have demonstrated impressive performance in various downstream tasks. Given that annotating medical data is time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2023-07-13 Yuhao Wang

Accurate prediction of cardiovascular diseases remains imperative for early diagnosis and intervention, necessitating robust and precise predictive models. Recently, there has been a growing interest in multi-modal learning for uncovering…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Francesco Girlanda , Olga Demler , Bjoern Menze , Neda Davoudi

The electrocardiogram (ECG) is a key diagnostic tool in cardiovascular health. Single-lead ECG recording is integrated into both clinical-grade and consumer wearables. While self-supervised pretraining of foundation models on unlabeled ECGs…

Machine Learning · Computer Science 2025-12-03 Yuxuan Shu , Peter H. Charlton , Fahim Kawsar , Jussi Hernesniemi , Mohammad Malekzadeh

Predicting whether a treatment leads to meaningful improvement is a central challenge in personalized medicine, particularly when disease progression manifests as subtle visual changes over time. While data-driven deep learning (DL) offers…

Image and Video Processing · Electrical Eng. & Systems 2025-11-21 Jana Armouti , Nikhil Madaan , Rohan Panda , Tom Fox , Laura Hutchins , Amita Krishnan , Ricardo Rodriguez , Bennett DeBoisblanc , Deva Ramanan , John Galeotti , Gautam Gare

We propose the Uncertainty Contrastive Framework (UCF), a Positive-Unlabeled (PU) representation learning framework that integrates uncertainty-aware contrastive loss, adaptive temperature scaling, and a self-attention-guided LSTM encoder…

Machine Learning · Computer Science 2025-12-11 Elias Hossain , Umesh Biswas , Charan Gudla , Sai Phani Parsa

Time series anomaly detection holds notable importance for risk identification and fault detection across diverse application domains. Unsupervised learning methods have become popular because they have no requirement for labels. However,…

Machine Learning · Computer Science 2025-05-05 Wenxin Zhang , Xiaojian Lin , Wenjun Yu , Guangzhen Yao , jingxiang Zhong , Yu Li , Renda Han , Songcheng Xu , Hao Shi , Cuicui Luo

Semi-supervised learning has demonstrated great potential in medical image segmentation by utilizing knowledge from unlabeled data. However, most existing approaches do not explicitly capture high-level semantic relations between distant…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Qianying Liu , Xiao Gu , Paul Henderson , Fani Deligianni

Contrastive learning, commonly applied in large-scale multimodal models, often relies on data from diverse and often unreliable sources, which can include misaligned or mislabeled text-image pairs. This frequently leads to robustness issues…

Machine Learning · Computer Science 2025-02-04 Lijie Hu , Chenyang Ren , Huanyi Xie , Khouloud Saadi , Shu Yang , Zhen Tan , Jingfeng Zhang , Di Wang

It is increasingly common to collect data of multiple different types on the same set of samples. Our focus is on studying relationships between such multiview features and responses. A motivating application arises in the context of…

Machine Learning · Statistics 2026-01-26 Niccolo Anceschi , Federico Ferrari , David B. Dunson , Himel Mallick

Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…

Computer Vision and Pattern Recognition · Computer Science 2025-01-06 Yifei Chen , Shenghao Zhu , Zhaojie Fang , Chang Liu , Binfeng Zou , Yuhe Wang , Shuo Chang , Fan Jia , Feiwei Qin , Jin Fan , Yong Peng , Changmiao Wang

Existing studies on disease diagnostic models focus either on diagnostic model learning for performance improvement or on the visual explanation of a trained diagnostic model. We propose a novel learn-explain-reinforce (LEAR) framework that…

Computer Vision and Pattern Recognition · Computer Science 2021-08-24 Kwanseok Oh , Jee Seok Yoon , Heung-Il Suk

Modern techniques like contrastive learning have been effectively used in many areas, including computer vision, natural language processing, and graph-structured data. Creating positive examples that assist the model in learning robust and…

Machine Learning · Computer Science 2024-02-19 Xu Zheng , Tianchun Wang , Wei Cheng , Aitian Ma , Haifeng Chen , Mo Sha , Dongsheng Luo

Understanding disease progression is a central clinical challenge with direct implications for early diagnosis and personalized treatment. While recent generative approaches have attempted to model progression, key mismatches remain:…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Hao Chen , Rui Yin , Yifan Chen , Qi Chen , Chao Li

In recent years, the use of edge information provided by knowledge graphs together with the advantages of higher-order connectivity in graph neural networks for recommendation systems has become an important research direction. However,…

Information Retrieval · Computer Science 2026-05-12 Zhifei Hu , Feng Xia

Modern medicine requires generalised approaches to the synthesis and integration of multimodal data, often at different biological scales, that can be applied to a variety of evidence structures, such as complex disease analyses and…

Quantitative Methods · Quantitative Biology 2019-11-11 Devin Taylor , Simeon Spasov , Pietro Liò

Deep learning has shown significant potential in diagnosing neurodegenerative diseases from MRI data. However, most existing methods rely heavily on large volumes of labeled data and often yield representations that lack interpretability.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Fangqi Cheng , Yingying Zhao , Xiaochen Yang

Medical image classification is one of the most important tasks for computer-aided diagnosis. Deep learning models, particularly convolutional neural networks, have been successfully used for disease classification from medical images,…

Computer Vision and Pattern Recognition · Computer Science 2023-05-05 Md. Atik Ahamed , Jin Chen , Abdullah-Al-Zubaer Imran
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