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We present a high-throughput, end-to-end pipeline for organic crystal structure prediction (CSP) -- the problem of identifying the stable crystal structures that will form from a given molecule based only on its molecular composition. Our…

Materials Science · Physics 2023-12-12 Amit Kadan , Kevin Ryczko , Andrew Wildman , Rodrigo Wang , Adrian Roitberg , Takeshi Yamazaki

Liquid crystals are synthetic and biological viscoelastic anisotropic soft matter materials that combine liquid fluidity with crystal anisotropy and find use in optical devices, sensor/actuators, lubrication, super-fibers. Frequently…

Soft Condensed Matter · Physics 2013-11-22 Ezequiel R. Soule , Alejandro D. Rey

We report a numerical simulation of the phase diagram of a simple model for membrane proteins constrained to move in a plane. In analogy with the corresponding three dimensional models, the liquid-gas transition becomes metastable as the…

Soft Condensed Matter · Physics 2009-10-31 Massimo G. Noro , Daan Frenkel

(Shortened) We use N-body simulations to investigate the structure and dynamical evolution of dark matter halos in galaxy clusters. Our sample consists of nine massive halos from an EdS universe with scale free power spectrum and n = -1.…

Astrophysics · Physics 2015-06-24 Giuseppe Tormen , Francois R. Bouchet , Simon D. M. White

Point defects in real crystals at finite temperatures are inevitable. Their dynamics severely influence the mechanical properties of crystals under shear giving rise to nonlinear effects such as ductility. Therefore, it is crucial to…

Soft Condensed Matter · Physics 2021-02-02 Gaurav P. Shrivastav , Gerhard Kahl

The investigation of collective behaviour in dense assemblies of self-propelled active particles has been motivated by a wide range of biological phenomena. Of particular interest are dynamical transitions of cellular and sub-cellular…

Soft Condensed Matter · Physics 2023-12-05 Yagyik Goswami , G. V. Shivashankar , Srikanth Sastry

Controlled crystallization, melting and vitrification are important fundamental processes in nature and technology. However, the microscopic details of these fundamental phenomena still lack understanding, in particular how the cooling rate…

Soft Condensed Matter · Physics 2024-07-08 M. P. M. Schelling , T. W. J. Verouden , T. C. M. Stevens , J. -M. Meijer

Evidence is mounting that the small bodies of our Solar System, such as comets and asteroids, have at least partially inherited their chemical composition from the first phases of the Solar System formation. It then appears that the…

Phase separation is as familiar as watching vinegar separating from oil in vinegrette. The observation that phase separation of proteins and nucleic acids is widespread in living cells has opened an entire field of research into the…

Soft Condensed Matter · Physics 2022-06-16 Davide Michieletto , Mattia Marenda

Phase separation of various materials has been studied for one and a half centuries. In the last two decades, phase separation of proteins and nucleic acids has received enormous attention, due its relevance to cellular functions. However,…

Soft Condensed Matter · Physics 2026-05-28 Huan-Xiang Zhou

We employ a multi-phase smoothed particle hydrodynamics (SPH) method to study droplet dynamics in shear flow. With an extensive range of Reynolds number, capillary number, wall confinement, and density/viscosity ratio between the droplet…

Fluid Dynamics · Physics 2023-07-07 Kuiliang Wang , Hong Liang , Chong Zhao , Xin Bian

In this work, we use large-scale molecular dynamics simulations coupled to free energy calculations to identify for the first time a limit of stability (spinodal) and a change in the nucleation mechanism in aqueous NaCl solutions. This is a…

Chemical Physics · Physics 2019-05-01 Hao Jiang , Pablo G. Debenedetti , Athanassios Z. Panagiotopoulos

We report on the phase behavior of an aqueous binary charged sphere suspension under exhaustively deionized conditions as a function of number fraction of small particles p and total number density n. The mixture of size ratio 0.557…

Soft Condensed Matter · Physics 2010-05-19 Nina J. Lorenz , Hans Joachim Schoepe , Thomas Palberg

The ability to reliably predict the structures and stabilities of a molecular crystal and its polymorphs without any prior experimental information would be an invaluable tool for a number of fields, with specific and immediate applications…

In a previous study, dissipative particle dynamics simulation was used to qualitatively clarify the phase diagram of the amphiphilic molecule hexaethylene glycol dodecyl ether (C12E6). In the present study, the hydrophilicity dependence of…

Soft Condensed Matter · Physics 2015-06-25 Hiroaki Nakamura , Yuichi Tamura

We employ a multiscale computational approach to investigate the condensation process of the C-terminal low-complexity region of the Caprin1 protein as a function of increasing ATP concentration for three states: the initial mixed state,…

Biological Physics · Physics 2025-09-10 Maria Tsanai , Teresa Head-Gordon

A novel method for crystal structure prediction, based on metadynamics and evolutionary algorithms, is presented here. This technique can be used to produce efficiently both the ground state and metastable states easily reachable from a…

Materials Science · Physics 2012-06-08 Qiang Zhu , Artem R. Oganov , Andriy O. Lyakhov

Understanding the pathways to crystallization during the deposition of a vapor phase on a cold solid substrate is of great interest in industry, e.g., for the realization of electronic devices made of crystallites-free glassy materials, as…

Soft Condensed Matter · Physics 2023-10-03 Fabio Leoni , Hajime Tanaka , John Russo

By molecular-dynamics simulations, we have studied the devitrification (or crystallization) of aged hard-sphere glasses. First, we find that the dynamics of the particles are intermittent: Quiescent periods, when the particles simply…

Soft Condensed Matter · Physics 2014-04-03 Eduardo Sanz , Chantal Valeriani , Emanuela Zaccarelli , Wilson C K Poon , Michael E Cates , Peter N Pusey

Understanding the mechanisms underlying crystal formation is crucial. For most systems, crystallization typically goes through a nucleation process that involves dynamics that happen at short time and length scales. Due to this, molecular…

Statistical Mechanics · Physics 2025-11-04 Steven W. Hall , Porhouy Minh , Sapna Sarupria