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Recent technological advances in healthcare have led to unprecedented growth in patient data quantity and diversity. While artificial intelligence (AI) models have shown promising results in analyzing individual data modalities, there is…

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Generating realistic training data for supervised learning remains a significant challenge in artificial intelligence, particularly in domains where large, expert-labeled datasets are scarce or costly to obtain. This is especially true for…

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Understanding the mechanisms of interactions within cells, tissues, and organisms is crucial to driving developments across biology and medicine. Mathematical modeling is an essential tool for simulating biological systems and revealing…

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Diabetes is a worldwide health issue affecting millions of people. Machine learning methods have shown promising results in improving diabetes prediction, particularly through the analysis of diverse data types, namely gene expression data.…

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As the availability of omics data has increased in the last few years, more multi-omics data have been generated, that is, high-dimensional molecular data consisting of several types such as genomic, transcriptomic, or proteomic data, all…

Genomics · Quantitative Biology 2023-02-09 Roman Hornung , Frederik Ludwigs , Jonas Hagenberg , Anne-Laure Boulesteix

Healthcare systems generate diverse multimodal data, including Electronic Health Records (EHR), clinical notes, and medical images. Effectively leveraging this data for clinical prediction is challenging, particularly as real-world samples…

Machine Learning · Computer Science 2025-09-01 Xiaoyang Wang , Christopher C. Yang

Multimodal clinical data are characterized by high dimensionality, heterogeneous representations, and structured missingness, posing significant challenges for predictive modeling, data integration, and interpretability. We propose BIONIC…

Social problems stemming from the shortage of radiologists are intensifying, and artificial intelligence is being highlighted as a potential solution. Recently emerging large-scale generative AI has expanded from large language models…

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Data is a precious resource in today's society, and is generated at an unprecedented and constantly growing pace. The need to store, analyze, and make data promptly available to a multitude of users introduces formidable challenges in…

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Devising deep latent variable models for multi-modal data has been a long-standing theme in machine learning research. Multi-modal Variational Autoencoders (VAEs) have been a popular generative model class that learns latent representations…

Machine Learning · Statistics 2024-09-25 Marcel Hirt , Domenico Campolo , Victoria Leong , Juan-Pablo Ortega

Many, if not most, systems of interest in science are naturally described as nonlinear dynamical systems. Empirically, we commonly access these systems through time series measurements. Often such time series may consist of discrete random…

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The rapid evolution of deep learning has significantly advanced the field of medical image analysis. However, despite these achievements, the further enhancement of deep learning models for medical image analysis faces a significant…

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Multi-sensor fusion plays a critical role in enhancing perception for autonomous driving, overcoming individual sensor limitations, and enabling comprehensive environmental understanding. This paper first formalizes multi-sensor fusion…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Chuheng Wei , Ziye Qin , Ziyan Zhang , Guoyuan Wu , Matthew J. Barth

Recent breakthroughs in high-resolution imaging of biomolecules in solution with cryo-electron microscopy (cryo-EM) have unlocked new doors for the reconstruction of molecular volumes, thereby promising further advances in biology,…

Image and Video Processing · Electrical Eng. & Systems 2022-05-27 Claire Donnat , Axel Levy , Frederic Poitevin , Ellen Zhong , Nina Miolane

Due to complex experimental settings, missing values are common in biomedical data. To handle this issue, many methods have been proposed, from ignoring incomplete instances to various data imputation approaches. With the recent rise of…

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Multiple imputation has become one of the standard methods in drawing inferences in many incomplete data applications. Applications of multiple imputation in relatively more complex settings, such as high-dimensional clustered data, require…

Methodology · Statistics 2025-04-08 Qiushuang Li , Recai Yucel

This paper provides a survey of the latest developments in visual signal coding and processing with generative models. Specifically, our focus is on presenting the advancement of generative models and their influence on research in the…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Zhibo Chen , Heming Sun , Li Zhang , Fan Zhang

This survey provides a comprehensive overview of recent advances in multimodal alignment and fusion within the field of machine learning, driven by the increasing availability and diversity of data modalities such as text, images, audio,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Songtao Li , Hao Tang

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Model-based approaches for image reconstruction, analysis and interpretation have made significant progress over the last decades. Many of these approaches are based on either mathematical, physical or biological models. A challenge for…

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