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Systems biology and systems neurophysiology in particular have recently emerged as powerful tools for a number of key applications in the biomedical sciences. Nevertheless, such models are often based on complex combinations of multiscale…

Neural and Evolutionary Computing · Computer Science 2022-09-27 Matteo Ferrante , Andera Duggento , Nicola Toschi

Physics-informed neural networks (PINNs) have gained prominence in recent years and are now effectively used in a number of applications. However, their performance remains unstable due to the complex landscape of the loss function. To…

Machine Learning · Computer Science 2025-09-30 Dmitry Bylinkin , Mikhail Aleksandrov , Savelii Chezhegov , Aleksandr Beznosikov

Physics-Informed Neural Networks (PINNs) have emerged as a powerful tool for integrating physics-based constraints and data to address forward and inverse problems in machine learning. Despite their potential, the implementation of PINNs…

Optimization and Control · Mathematics 2024-12-19 Alan Williams , Christopher Leon , Alexander Scheinker

Physics-informed neural networks (PINNs) represent a new paradigm for solving partial differential equations (PDEs) by integrating physical laws into the learning process of neural networks. However, ensuring that such frameworks fully…

Machine Learning · Computer Science 2025-12-12 Nanxi Chen , Sifan Wang , Rujin Ma , Airong Chen , Chuanjie Cui

The energy management problem in the context of smart grids is inherently complex due to the interdependencies among diverse system components. Although Reinforcement Learning (RL) has been proposed for solving Optimal Power Flow (OPF)…

Machine Learning · Computer Science 2026-02-24 Abeer Alsheikhi , Amirfarhad Farhadi , Azadeh Zamanifar

We implement a Physics-Informed Neural Network (PINN) for solving the two-dimensional Burgers equations. This type of model can be trained with no previous knowledge of the solution; instead, it relies on evaluating the governing equations…

Physics-informed neural networks (PINNs) constitute a flexible deep learning approach for solving partial differential equations (PDEs), which model phenomena ranging from heat conduction to quantum mechanical systems. Despite their…

Machine Learning · Computer Science 2026-03-17 Aleksander Krasowski , René P. Klausen , Aycan Celik , Sebastian Lapuschkin , Wojciech Samek , Jonas Naujoks

Physics-informed neural network (PINN) has recently gained increasing interest in computational mechanics. In this work, we present a detailed introduction to programming PINN-based computational solid mechanics. Besides, two prevailingly…

Computational Engineering, Finance, and Science · Computer Science 2023-04-11 Jinshuai Bai , Hyogu Jeong , C. P. Batuwatta-Gamage , Shusheng Xiao , Qingxia Wang , C. M. Rathnayaka , Laith Alzubaidi , Gui-Rong Liu , Yuantong Gu

In recent engineering applications using deep learning, physics-informed neural network (PINN) is a new development as it can exploit the underlying physics of engineering systems. The novelty of PINN lies in the use of partial differential…

Computational Engineering, Finance, and Science · Computer Science 2026-02-26 Kart Leong Lim , Rahul Dutta , Mihai Rotaru

Physics-informed neural networks (PINNs) are a promising approach that combines the power of neural networks with the interpretability of physical modeling. PINNs have shown good practical performance in solving partial differential…

Statistics Theory · Mathematics 2026-01-26 Nathan Doumèche , Gérard Biau , Claire Boyer

Physics-informed neural networks (PINNs) have emerged as a promising mesh-free paradigm for solving partial differential equations, yet adoption in science and engineering is limited by slow training and modest accuracy relative to modern…

Computational Engineering, Finance, and Science · Computer Science 2026-02-24 Pao-Hsiung Chiu , Jian Cheng Wong , Chin Chun Ooi , Chang Wei , Yuchen Fan , Yew-Soon Ong

Efficient simulation of Laser Powder Bed Fusion (LPBF) is crucial for process prediction due to the lasting issue of high computational cost associated with traditional numerical methods such as finite element analysis (FEA). While a…

Machine Learning · Computer Science 2026-05-25 R. Sharma , Y. B. Guo

While the popularity of physics-informed neural networks (PINNs) is steadily rising, to this date, PINNs have not been successful in simulating multi-scale and singular perturbation problems. In this work, we present a new training paradigm…

Machine Learning · Computer Science 2024-03-27 Zhiwei Fang , Sifan Wang , Paris Perdikaris

We propose a self-supervised physics-informed neural network (PINN) framework that adaptively balances physics-based and data-driven supervision for scientific machine learning under data scarcity. Unlike prior PINNs that rely on fixed or…

Machine Learning · Computer Science 2026-05-08 Reza Pirayeshshirazinezhad

Physics-Informed Neural Networks present a novel approach in SciML that integrates physical laws in the form of partial differential equations directly into the NN through soft constraints in the loss function. This work studies the…

Neural and Evolutionary Computing · Computer Science 2026-02-17 Suhas Suresh Bharadwaj , Reuben Thomas Thovelil

Physics-Informed Neural Networks (PINNs) are a class of deep learning neural networks that learn the response of a physical system without any simulation data, and only by incorporating the governing partial differential equations (PDEs) in…

Machine Learning · Computer Science 2023-12-19 Rini J. Gladstone , Mohammad A. Nabian , N. Sukumar , Ankit Srivastava , Hadi Meidani

Data-driven discovery of governing equations in computational science has emerged as a new paradigm for obtaining accurate physical models and as a possible alternative to theoretical derivations. The recently developed physics-informed…

Machine Learning · Computer Science 2023-10-18 Zongren Zou , Xuhui Meng , George Em Karniadakis

In this study, the capabilities of the Physics-Informed Neural Network (PINN) method are investigated for three major tasks: modeling, simulation, and optimization in the context of the heat conduction problem. In the modeling phase, the…

Computational Physics · Physics 2025-10-31 Ehsan Ghaderi , Mohamad Ali Bijarchi , Siamak Kazemzadeh Hannani , Ali Nouri Boroujerdi

Quantum many-body systems are of great interest for many research areas, including physics, biology and chemistry. However, their simulation is extremely challenging, due to the exponential growth of the Hilbert space with the system size,…

Quantum Physics · Physics 2024-10-23 Lorenzo Brevi , Antonio Mandarino , Enrico Prati

Large-scale wave field reconstruction requires precise solutions but faces challenges with computational efficiency and accuracy. The physics-based numerical methods like Finite Element Method (FEM) provide high accuracy but struggle with…

Machine Learning · Computer Science 2026-03-04 Huiwen Zhang , Feng Ye , Chu Ma