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Intensive longitudinal biomarker data are increasingly common in scientific studies that seek temporally granular understanding of the role of behavioral and physiological factors in relation to outcomes of interest. Intensive longitudinal…

Methodology · Statistics 2024-01-17 Mingyan Yu , Zhenke Wu , Margaret Hicken , Michael R. Elliott

The so-called gut-brain axis has stimulated extensive research on microbiomes. One focus is to assess the association between certain clinical outcomes and the relative abundances of gut microbes, which can be presented as sub-compositional…

Methodology · Statistics 2020-06-02 Xiaokang Liu , Xiaomei Cong , Gen Li , Kendra Maas , Kun Chen

Obesity is one of the leading health concerns in the United States. Researchers and health care providers are interested in understanding factors affecting obesity and detecting the likelihood of obesity as early as possible. In this paper,…

Applications · Statistics 2017-08-24 Moumita Bhattacharya , Deborah Ehrenthal , Hagit Shatkay

Joint modeling of longitudinal and survival data has become increasingly important in medical research, particularly for understanding disease progression in chronic conditions where both repeated biomarker measurements and time-to-event…

Methodology · Statistics 2025-12-30 Nithisha Suryadevara , Vivek Reddy Srigiri

Count outcomes in longitudinal studies are frequent in clinical and engineering studies. In frequentist and Bayesian statistical analysis, methods such as Mixed linear models allow the variability or correlation within individuals to be…

Methodology · Statistics 2024-07-15 Alejandra Estefanía Patiño Hoyos , Johnatan Cardona Jiménez

Many applications involve data with qualitative and quantitative responses. When there is an association between the two responses, a joint model will provide improved results than modeling them separately. In this paper, we propose a…

Methodology · Statistics 2026-05-12 Xiaoning Kang , Shyam Ranganathan , Lulu Kang , Julia Gohlke , Xinwei Deng

Bayesian estimation is increasingly popular for performing model based inference to support policymaking. These data are often collected from surveys under informative sampling designs where subject inclusion probabilities are designed to…

Methodology · Statistics 2018-07-13 Luis G. Leon-Novelo , Terrance D. Savitsky

Current alignment-based methods for classification in geometric morphometrics do not generally address the classification of new individuals that were not part of the study sample. However, in the context of infant and child nutritional…

Applications · Statistics 2026-01-23 Laura Medialdea , Ana Arribas-Gil , Álvaro Pérez-Romero , Amador Gómez

Building on Dryden et al. (2021), this note presents the Bayesian estimation of a regression model for size-and-shape response variables with Gaussian landmarks. Our proposal fits into the framework of Bayesian latent variable models and…

Methodology · Statistics 2024-06-11 Antonio Di Noia , Gianluca Mastrantonio , Giovanna Jona Lasinio

This work is motivated by analyses of longitudinal data collected from participants in the Quebec Longitudinal Study of Child Development (QLSCD) and the Quebec Newborn Twin Study (QNTS) to identify important genetic predictors for…

This manuscript presents a novel Bayesian varying coefficient quantile regression (BVCQR) model designed to assess the longitudinal effects of chemical exposure mixtures on children's neurodevelopment. Recognizing the complexity and…

Applications · Statistics 2024-04-22 Wei Jia , Roman Jandarov

The identification of sets of co-regulated genes that share a common function is a key question of modern genomics. Bayesian profile regression is a semi-supervised mixture modelling approach that makes use of a response to guide inference…

I consider how cell shape and environmental geometry affect the rate of nutrient capture and the consequent maximum growth rate of a cell, focusing on rod-like species like \textit{E.\ coli}. Simple modeling immediately implies that it is…

Biological Physics · Physics 2014-03-27 Jonathan Landy

Standard causal inference characterizes treatment effect through averages, but the counterfactual distributions could be different in not only the central tendency but also spread and shape. To provide a comprehensive evaluation of…

Methodology · Statistics 2022-11-04 Steven G. Xu , Shu Yang , Brian J. Reich

Understanding how biomarker distributions evolve over time is a central challenge in digital health and chronic disease monitoring. In diabetes, changes in the distribution of glucose measurements can reveal patterns of disease progression…

Machine Learning · Statistics 2026-03-26 Antonio Álvarez-López , Marcos Matabuena

Background: Childhood and adolescent overweight and obesity remain major public health concerns in the United States and are shaped by behavioral, household, and community factors. Their joint predictive structure at the population level…

Artificial Intelligence · Computer Science 2026-02-25 Joyanta Jyoti Mondal

Within-individual variability of health indicators measured over time is becoming commonly used to inform about disease progression. Simple summary statistics (e.g. the standard deviation for each individual) are often used but they are not…

Dietary patterns synthesize multiple related diet components, which can be used by nutrition researchers to examine diet-disease relationships. Latent class models (LCMs) have been used to derive dietary patterns from dietary intake…

Methodology · Statistics 2025-04-11 Mengbing Li , Briana Stephenson , Zhenke Wu

We propose a novel approach to the estimation of multiple Graphical Models to analyse temporal patterns of association among a set of metabolites over different groups of patients. Our motivating application is the Southall And Brent…

Growth charts are widely used in pediatric care for assessing childhood body size measurements (e.g., height or weight). The existing growth charts screen one body size at a single given age. However, when a child has multiple measures over…

Applications · Statistics 2015-09-18 Wenfei Zhang , Ying Wei
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