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Related papers: Human Genome Book: Words, Sentences and Paragraphs

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The intricate relationship between genetic variation and human diseases has been a focal point of medical research, evidenced by the identification of risk genes regarding specific diseases. The advent of advanced genome sequencing…

Quantitative Methods · Quantitative Biology 2024-01-19 Jiayu Chang , Shiyu Wang , Chen Ling , Zhaohui Qin , Liang Zhao

Sentence embedding is an important research topic in natural language processing. It is essential to generate a good embedding vector that fully reflects the semantic meaning of a sentence in order to achieve an enhanced performance for…

Computation and Language · Computer Science 2018-10-16 Myeongjun Jang , Pilsung Kang

Predicting gene function from its DNA sequence is a fundamental challenge in biology. Many deep learning models have been proposed to embed DNA sequences and predict their enzymatic function, leveraging information in public databases…

In medical fields, text classification is one of the most important tasks that can significantly reduce human workload through structured information digitization and intelligent decision support. Despite the popularity of learning-based…

Computation and Language · Computer Science 2020-12-15 J Liu , R Bai , Z Lu , P Ge , D Liu , Uwe Aickelin

We introduce recurrent neural network grammars, probabilistic models of sentences with explicit phrase structure. We explain efficient inference procedures that allow application to both parsing and language modeling. Experiments show that…

Computation and Language · Computer Science 2016-10-13 Chris Dyer , Adhiguna Kuncoro , Miguel Ballesteros , Noah A. Smith

Large language models (LLMs) trained on text demonstrated remarkable results on natural language processing (NLP) tasks. These models have been adapted to decipher the language of DNA, where sequences of nucleotides act as "words" that…

In recent years, several machine learning approaches have been proposed to predict gene expression and epigenetic signals from the DNA sequence alone. These models are often used to deduce, and, to some extent, assess putative new…

Genomics · Quantitative Biology 2023-04-26 Laurent Bréhélin

In this article, we present a fresh perspective on language, combining ideas from various sources, but mixed in a new synthesis. As in the minimalist program, the question is whether we can formulate an elegant formalism, a universal…

Computation and Language · Computer Science 2023-03-10 Loe Feijs

Large-scale language models (LMs) pretrained on massive corpora of text, such as GPT-2, are powerful open-domain text generators. However, as our systematic examination reveals, it is still challenging for such models to generate coherent…

Computation and Language · Computer Science 2021-04-15 Bowen Tan , Zichao Yang , Maruan AI-Shedivat , Eric P. Xing , Zhiting Hu

Human body part parsing, or human semantic part segmentation, is fundamental to many computer vision tasks. In conventional semantic segmentation methods, the ground truth segmentations are provided, and fully convolutional networks (FCN)…

Computer Vision and Pattern Recognition · Computer Science 2018-05-14 Hao-Shu Fang , Guansong Lu , Xiaolin Fang , Jianwen Xie , Yu-Wing Tai , Cewu Lu

Generative models reliant on sequential autoregression have been at the forefront of language generation for an extensive period, particularly following the introduction of widely acclaimed transformers. Despite its excellent performance,…

Computation and Language · Computer Science 2024-06-21 Yaguang Li , Xin Chen

The rapid advancements in large language models (LLMs) have significantly improved their ability to generate natural language, making texts generated by LLMs increasingly indistinguishable from human-written texts. Recent research has…

Computation and Language · Computer Science 2024-12-05 Sergio E. Zanotto , Segun Aroyehun

In recent years, the use of deep learning in language models gained much attention. Some research projects claim that they can generate text that can be interpreted as human-writing, enabling new possibilities in many application areas.…

Computation and Language · Computer Science 2021-01-13 Juan Cruz-Benito , Sanjay Vishwakarma , Francisco Martin-Fernandez , Ismael Faro

This work studies the task of glossification, of which the aim is to em transcribe natural spoken language sentences for the Deaf (hard-of-hearing) community to ordered sign language glosses. Previous sequence-to-sequence language models…

Computation and Language · Computer Science 2021-12-20 Dongxu Li , Chenchen Xu , Liu Liu , Yiran Zhong , Rong Wang , Lars Petersson , Hongdong Li

Genome data are crucial in modern medicine, offering significant potential for diagnosis and treatment. Thanks to technological advancements, many millions of healthy and diseased genomes have already been sequenced; however, obtaining the…

Genomics · Quantitative Biology 2024-06-18 Teddy Lazebnik , Liron Simon-Keren

Data of sequential nature arise in many application domains in forms of, e.g. textual data, DNA sequences, and software execution traces. Different research disciplines have developed methods to learn sequence models from such datasets: (i)…

Machine Learning · Statistics 2018-11-02 Niek Tax , Irene Teinemaa , Sebastiaan J. van Zelst

The rapid advance of DNA sequencing technologies has yielded databases of thousands of genomes. To search and index these databases effectively, it is important that we take advantage of the similarity between those genomes. Several authors…

Data Structures and Algorithms · Computer Science 2014-12-05 Travis Gagie , Simon J. Puglisi

We show that protein sequences can be thought of as sentences in natural language processing and can be parsed using the existing Quantum Natural Language framework into parameterized quantum circuits of reasonable qubits, which can be…

Modeling genomic sequences faces two unsolved challenges: the information density varies widely across different regions, while there is no clearly defined minimum vocabulary unit. Relying on either four primitive bases or independently…

Genomics · Quantitative Biology 2025-11-20 Siyuan Li , Kai Yu , Anna Wang , Zicheng Liu , Chang Yu , Jingbo Zhou , Qirong Yang , Yucheng Guo , Xiaoming Zhang , Stan Z. Li

Reference-guided DNA sequencing and alignment is an important process in computational molecular biology. The amount of DNA data grows very fast, and many new genomes are waiting to be sequenced while millions of private genomes need to be…