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Living systems can be understood as organized entities that capture, transform, and reproduce information. Classical gene-centered models explain adaptation through frequency changes driven by differential fitness, yet they often overlook…

Populations and Evolution · Quantitative Biology 2026-01-21 Antonio Carvajal-Rodríguez

Partial information decomposition (PID) partitions the information that a set of sources has about a target variable into synergistic, unique, and redundant contributions. This information-theoretic tool has recently attracted attention due…

Information Theory · Computer Science 2020-10-15 Abdullah Makkeh , Dirk Oliver Theis , Raul Vicente

Signal transduction, or signal-processing capability, is a fundamental property of nature that manifests universally across systems of different scales -- from quantum behaviour to the biological. This includes the detection of…

Signal Processing · Electrical Eng. & Systems 2023-09-12 Dorje C. Brody , Anthony J. Trewavas

Early warning indicators often suffer from the shortness and coarse-graining of real-world time series. Furthermore, the typically strong and correlated noise contributions in real applications are severe drawbacks for statistical measures.…

Data Analysis, Statistics and Probability · Physics 2026-03-03 Martin Heßler , Oliver Kamps

Of the various attempts to generalize information theory to multiple variables, the most widely utilized, interaction information, suffers from the problem that it is sometimes negative. Here we reconsider from first principles the general…

Information Theory · Computer Science 2010-04-16 Paul L. Williams , Randall D. Beer

In the study of complex dynamical systems, understanding and accurately modeling the underlying physical processes is crucial for predicting system behavior and designing effective interventions. Yet real-world systems exhibit pronounced…

Machine Learning · Statistics 2025-07-15 Ridwan Olabiyi , Han Hu , Ashif Iquebal

Partial Information Decomposition (PID) was proposed by Williams and Beer in 2010 as a tool for analyzing fine-grained interactions between multiple random variables, and has since found numerous applications ranging from neuroscience to…

Information Theory · Computer Science 2025-10-23 Aobo Lyu , Andrew Clark , Netanel Raviv

The ability of organisms to accurately sense their environment and respond accordingly is critical for evolutionary success. However, exactly how the sensory ability influences fitness is a topic of active research, while the necessity of a…

Populations and Evolution · Quantitative Biology 2020-11-11 Alexander S. Moffett , Nigel Wallbridge , Carrol Plummer , Andrew W. Eckford

Adaptation is used by biological sensory systems to respond to a wide range of environmental signals, by adapting their response properties to the statistics of the stimulus in order to maximize information transmission. We derive rules of…

Neurons and Cognition · Quantitative Biology 2021-04-14 Daniele Conti , Thierry Mora

How can the information that a set ${X_{1},...,X_{n}}$ of random variables contains about another random variable $S$ be decomposed? To what extent do different subgroups provide the same, i.e. shared or redundant, information, carry unique…

Information Theory · Computer Science 2014-06-18 Nils Bertschinger , Johannes Rauh , Eckehard Olbrich , Jürgen Jost

Antifragility characterizes the benefit of a dynamical system derived from the variability in environmental perturbations. Antifragility carries a precise definition that quantifies a system's output response to input variability. Systems…

Populations and Evolution · Quantitative Biology 2023-12-22 Cristian Axenie , Oliver López-Corona , Michail A. Makridis , Meisam Akbarzadeh , Matteo Saveriano , Alexandru Stancu , Jeffrey West

We present an approach for autonomous sensor control for information gathering under partially observable, dynamic and sparsely sampled environments that maximizes information about entities present in that space. We describe our approach…

Artificial Intelligence · Computer Science 2023-05-24 J. Brian Burns , Aravind Sundaresan , Pedro Sequeira , Vidyasagar Sadhu

The nonlinearity of dynamics in systems biology makes it hard to infer them from experimental data. Simple linear models are computationally efficient, but cannot incorporate these important nonlinearities. An adaptive method based on the…

Quantitative Methods · Quantitative Biology 2015-08-19 Bryan C. Daniels , Ilya Nemenman

Predicting the response of nonlinear dynamical systems subject to random, broadband excitation is important across a range of scientific disciplines, such as structural dynamics and neuroscience. Building data-driven models requires…

Machine Learning · Computer Science 2024-09-27 Joseph Massingham , Ole Nielsen , Tore Butlin

Intracellular biochemical networks fluctuate dynamically due to various internal and external sources of fluctuation. Dissecting the fluctuation into biologically relevant components is important for understanding how a cell controls and…

Molecular Networks · Quantitative Biology 2016-02-17 Tetsuya J. Kobayashi , Ryo Yokota , Kazuyuki Aihara

Statistical properties of environments experienced by biological signaling systems in the real world change, which necessitate adaptive responses to achieve high fidelity information transmission. One form of such adaptive response is gain…

Molecular Networks · Quantitative Biology 2012-05-01 Ilya Nemenman

A dynamic model for failures in biological organisms is proposed and studied both analytically and numerically. Each cell in the organism becomes dead under sufficiently strong stress, and is then allowed to be healed with some probability.…

Cell Behavior · Quantitative Biology 2009-11-11 J. Choi , M. Y. Choi , B. -G. Yoon

The constituents of a complex system exchange information to function properly. Their signalling dynamics often leads to the appearance of emergent phenomena, such as phase transitions and collective behaviors. While information exchange…

Physics and Society · Physics 2020-11-18 Arsham Ghavasieh , Carlo Nicolini , Manlio De Domenico

In a topological dynamical system the complexity of an orbit is a measure of the amount of information (algorithmic information content) that is necessary to describe the orbit. This indicator is invariant up to topological conjugation. We…

Dynamical Systems · Mathematics 2007-05-23 Stefano Galatolo

Resilience is widely recognized as an important design goal though it is one that seems to escape a general and consensual understanding. Often mixed up with other system attributes; traditionally used with different meanings in as many…

Computers and Society · Computer Science 2014-01-23 Vincenzo De Florio