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The dynamics of many-body systems can often be captured in terms of only a few relevant variables. Mathematical and numerical approaches exist to identify these variables by exploiting a separation of time scales between slow relevant and…

Obtaining meaningful quantitative descriptions of the statistical dependence within multivariate systems is a difficult open problem. Recently, the Partial Information Decomposition (PID) was proposed to decompose mutual information (MI)…

Information Theory · Computer Science 2017-02-21 Robin A. A. Ince

Objective: This work introduces a framework for multivariate time series analysis aimed at detecting and quantifying collective emerging behaviors in the dynamics of physiological networks. Methods: Given a network system mapped by a vector…

Applications · Statistics 2025-02-04 Luca Faes , Gorana Mijatovic , Laura Sparacino , Alberto Porta

Since its introduction in 2011, the partial information decomposition (PID) has triggered an explosion of interest in the field of multivariate information theory and the study of emergent, higher-order ("synergistic") interactions in…

Information Theory · Computer Science 2024-02-14 Thomas F. Varley

In many neural systems anatomical motifs are present repeatedly, but despite their structural similarity they can serve very different tasks. A prime example for such a motif is the canonical microcircuit of six-layered neo-cortex, which is…

Neurons and Cognition · Quantitative Biology 2015-10-07 Michael Wibral , Viola Priesemann , Jim W. Kay , Joseph T. Lizier , William A. Phillips

Partial Information Decomposition (PID) is a principled and flexible method to unveil complex high-order interactions in multi-unit network systems. Though being defined exclusively for random variables, PID is ubiquitously applied to…

Natural physical, chemical, and biological dynamical systems are often complex, with heterogeneous components interacting in diverse ways. We show how simple graph neural networks can be designed to jointly learn the interaction rules and…

The apparent dichotomy between information-processing and dynamical approaches to complexity science forces researchers to choose between two diverging sets of tools and explanations, creating conflict and often hindering scientific…

Neurons and Cognition · Quantitative Biology 2022-01-26 Pedro A. M. Mediano , Fernando E. Rosas , Juan Carlos Farah , Murray Shanahan , Daniel Bor , Adam B. Barrett

Most information dynamics and statistical causal analysis frameworks rely on the common intuition that causal interactions are intrinsically pairwise -- every 'cause' variable has an associated 'effect' variable, so that a 'causal arrow'…

Neurons and Cognition · Quantitative Biology 2019-09-06 Pedro A. M. Mediano , Fernando Rosas , Robin L. Carhart-Harris , Anil K. Seth , Adam B. Barrett

Dynamic nonlinear systems exhibit distortions arising from coupled static and dynamic effects. Their intertwined nature poses major challenges for data-driven modeling. This paper presents a theoretical framework grounded in structured…

Machine Learning · Computer Science 2025-09-23 Sri Satish Krishna Chaitanya Bulusu , Mikko Sillanpää

Unlike many physical nonequilibrium systems, in biological systems, the coupling to external energy sources is not a fixed parameter but adaptively controlled by the system itself. We do not have theoretical frameworks that allow for such…

Populations and Evolution · Quantitative Biology 2025-06-30 Ankit Dhanuka , Avi I. Flamholz , Arvind Murugan , Akshit Goyal

An important issue during an engineering design process is to develop an understanding which design parameters have the most influence on the performance. Especially in the context of optimization approaches this knowledge is crucial in…

Information Theory · Computer Science 2024-10-28 Patricia Wollstadt , Sebastian Schmitt

Biochemistry, ecology, and neuroscience are examples of prominent fields aiming at describing interacting systems that exhibit non-trivial couplings to complex, ever-changing environments. We have recently shown that linear interactions and…

Statistical Mechanics · Physics 2022-08-10 Giorgio Nicoletti , Daniel Maria Busiello

In a system of three stochastic variables, the Partial Information Decomposition (PID) of Williams and Beer dissects the information that two variables (sources) carry about a third variable (target) into nonnegative information atoms that…

Information Theory · Computer Science 2017-08-30 Giuseppe Pica , Eugenio Piasini , Daniel Chicharro , Stefano Panzeri

This paper introduces a novel approach to quantifying ecological resilience in biological systems, particularly focusing on noisy systems responding to episodic disturbances with sudden adaptations. Incorporating concepts from…

Quantitative Methods · Quantitative Biology 2024-12-24 Jorge M. Ramirez , Juan M. Restrepo , Valerio Lucarini , David Weston

Real-world systems are characterized by complex interactions of their internal degrees of freedom, while living in ever-changing environments whose net effect is to act as additional couplings. Here, we introduce a paradigmatic interacting…

Statistical Mechanics · Physics 2021-11-23 Giorgio Nicoletti , Daniel Maria Busiello

Biological and living systems process information across spatiotemporal scales, exhibiting the hallmark ability to constantly modulate their behavior to ever-changing and complex environments. In the presence of repeated stimuli, a…

Statistical Mechanics · Physics 2025-02-04 Giorgio Nicoletti , Matteo Bruzzone , Samir Suweis , Marco Dal Maschio , Daniel Maria Busiello

The possibility that evolutionary forces -- together with a few fundamental factors such as thermodynamic constraints, specific computational features enabling information processing, and ecological processes -- might constrain the logic of…

Biological Physics · Physics 2025-12-30 Manlio De Domenico

In computer science, we can theoretically neatly separate transmission and processing of information, hardware and software, and programs and their inputs. This is much more intricate in biology, Nevertheless, I argue that Shannon's concept…

Populations and Evolution · Quantitative Biology 2020-11-02 Jürgen Jost

The capacity to adapt can greatly influence the success of systems that need to compensate for damaged parts, learn how to achieve robust performance in new environments, or exploit novel opportunities that originate from new technological…

Adaptation and Self-Organizing Systems · Physics 2011-12-15 James Whitacre , Axel Bender