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Purpose: Deformable Image Registration (DIR) can benefit from additional guidance using corresponding landmarks in the images. However, the benefits thereof are largely understudied, especially due to the lack of automatic landmark…

Computer Vision and Pattern Recognition · Computer Science 2023-02-28 Monika Grewal , Jan Wiersma , Henrike Westerveld , Peter A. N. Bosman , Tanja Alderliesten

We present HyperMorph, a learning-based strategy for deformable image registration that removes the need to tune important registration hyperparameters during training. Classical registration methods solve an optimization problem to find a…

Computer Vision and Pattern Recognition · Computer Science 2021-05-06 Andrew Hoopes , Malte Hoffmann , Bruce Fischl , John Guttag , Adrian V. Dalca

Deformable image registration is fundamental for many medical image analyses. A key obstacle for accurate image registration lies in image appearance variations such as the variations in texture, intensities, and noise. These variations are…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Mingyuan Meng , Lei Bi , Michael Fulham , David Dagan Feng , Jinman Kim

Deep learning based methods provide efficient solutions to medical image registration, including the challenging problem of diffeomorphic image registration. However, most methods register normal image pairs, facing difficulty handling…

Image and Video Processing · Electrical Eng. & Systems 2023-03-17 Ankita Joshi , Yi Hong

Recent successes in deep learning based deformable image registration (DIR) methods have demonstrated that complex deformation can be learnt directly from data while reducing computation time when compared to traditional methods. However,…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Sharib Ali , Jens Rittscher

A lot of deep learning (DL) research these days is mainly focused on improving quantitative metrics regardless of other factors. In human-centered applications, like skin lesion classification in dermatology, DL-driven clinical decision…

Image and Video Processing · Electrical Eng. & Systems 2023-09-01 Theodor Cheslerean-Boghiu , Melia-Evelina Fleischmann , Theresa Willem , Tobias Lasser

In this work we propose an adaptive Finite Element Method (FEM) formulation for the Deformable Image Registration problem (DIR) together with a residual-based a posteriori error estimator, whose efficiency and reliability are theoretically…

Numerical Analysis · Mathematics 2025-06-23 Nicolás A. Barnafi , Alberto F. Martın , Ricardo Ruiz-Baier

In adaptive radiotherapy, deformable image registration is often conducted between the planning CT and treatment CT (or cone beam CT) to generate a deformation vector field (DVF) for dose accumulation and contour propagation. The auto…

Medical Physics · Physics 2015-06-12 Xuejun Gu , Bin Dong , Jing Wang , John Yordy , Loren Mell , Xun Jia , Steve B. Jiang

In augmented reality (AR)-guided surgical navigation, preoperative organ models are superimposed onto the patient's intraoperative anatomy to visualize critical structures such as vessels and tumors. Accurate deformation modeling is…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Zheng Han , Jun Zhou , Jialun Pei , Jing Qin , Yingfang Fan , Qi Dou

We propose a non-intrusive Deep Learning-based Reduced Order Model (DL-ROM) capable of capturing the complex dynamics of mechanical systems showing inertia and geometric nonlinearities. In the first phase, a limited number of high fidelity…

Numerical Analysis · Mathematics 2021-11-25 Stefania Fresca , Giorgio Gobat , Patrick Fedeli , Attilio Frangi , Andrea Manzoni

Deformable image registration is crucial for aligning medical images in a nonlinear fashion across different modalities, allowing for precise spatial correspondence between varying anatomical structures. This paper presents NestedMorph, a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Gurucharan Marthi Krishna Kumar , Janine Mendola , Amir Shmuel

Recent developments in neural networks have improved deformable image registration (DIR) by amortizing iterative optimization, enabling fast and accurate DIR results. However, learning-based methods often face challenges with limited…

Image and Video Processing · Electrical Eng. & Systems 2025-06-26 Hang Zhang , Yuxi Zhang , Jiazheng Wang , Xiang Chen , Renjiu Hu , Xin Tian , Gaolei Li , Min Liu

Recently, deep learning methods have been widely used for tumor segmentation of multimodal medical images with promising results. However, most existing methods are limited by insufficient representational ability, specific modality number…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Jun Shi , Hongyu Kan , Shulan Ruan , Ziqi Zhu , Minfan Zhao , Liang Qiao , Zhaohui Wang , Hong An , Xudong Xue

An effective backbone network is important to deep learning-based Deformable Medical Image Registration (DMIR), because it extracts and matches the features between two images to discover the mutual correspondence for fine registration.…

Computer Vision and Pattern Recognition · Computer Science 2022-06-16 Jiacheng Shi , Yuting He , Youyong Kong , Jean-Louis Coatrieux , Huazhong Shu , Guanyu Yang , Shuo Li

Deformable medical image registration is an essential task in computer-assisted interventions. This problem is particularly relevant to oncological treatments, where precise image alignment is necessary for tracking tumor growth, assessing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Stefano Fogarollo , Gregor Laimer , Reto Bale , Matthias Harders

In this work, we introduce a fast and accurate method for unsupervised 3D medical image registration. This work is built on top of a recent algorithm SAM, which is capable of computing dense anatomical/semantic correspondences between two…

Image and Video Processing · Electrical Eng. & Systems 2021-09-27 Fengze Liu , Ke Yan , Adam Harrison , Dazhou Guo , Le Lu , Alan Yuille , Lingyun Huang , Guotong Xie , Jing Xiao , Xianghua Ye , Dakai Jin

We propose FlowReg, a deep learning-based framework for unsupervised image registration for neuroimaging applications. The system is composed of two architectures that are trained sequentially: FlowReg-A which affinely corrects for gross…

Computer Vision and Pattern Recognition · Computer Science 2021-09-02 Sergiu Mocanu , Alan R. Moody , April Khademi

Purpose: Evaluating deformable image registration (DIR) algorithms is vital for enhancing algorithm performance and gaining clinical acceptance. However, there's a notable lack of dependable DIR benchmark datasets for assessing DIR…

Medical Physics · Physics 2024-04-09 Zhendong Zhang , Edward Robert Criscuolo , Yao Hao , Deshan Yang

Most of the deep learning based medical image registration algorithms focus on brain image registration tasks.Compared with brain registration, the chest CT registration has larger deformation, more complex background and region over-lap.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Cheng Wang , Qiyu Gao , Fandong Zhang , Shu Zhang , Yizhou Yu

We propose approaches based on deep learning to localize objects in images when only a small training dataset is available and the images have low quality. That applies to many problems in medical image processing, and in particular to the…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Aaron Pries , Peter J. Schreier , Artur Lamm , Stefan Pede , Jürgen Schmidt