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Characterization of a patient clinical phenotype is central to biomedical informatics. ICD codes, assigned to inpatient encounters by coders, is important for population health and cohort discovery when clinical information is limited.…

The segmentation of kidney layer structures, including cortex, outer stripe, inner stripe, and inner medulla within human kidney whole slide images (WSI) plays an essential role in automated image analysis in renal pathology. However, the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Muhao Liu , Chenyang Qi , Shunxing Bao , Quan Liu , Ruining Deng , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Artificial intelligence and deep learning are increasingly applied in the clinical domain, particularly for early and accurate disease detection using medical imaging and sound. Due to limited trained personnel, there is a growing demand…

Image and Video Processing · Electrical Eng. & Systems 2025-09-30 Shahran Rahman Alve , Muhammad Zawad Mahmud , Samiha Islam , Mohammad Monirujjaman Khan

In the healthcare sector, the application of deep learning technologies has revolutionized data analysis and disease forecasting. This is particularly evident in the field of diabetes, where the deep analysis of Electronic Health Records…

Machine Learning · Computer Science 2024-12-06 Huadong Pang , Li Zhou , Yiping Dong , Peiyuan Chen , Dian Gu , Tianyi Lyu , Hansong Zhang

This work proposed a novel deep registration pipeline for 3D CT and 2D U/S kidney scans of free breathing, which consists of a feature network, and a 3D-2D CNN-based registration network. The feature network has handcraft texture feature…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Chi Yanling , Xu Yuyu , Liu Huiying , Wu Xiaoxiang , Liu Zhiqiang , Mao Jiawei , Xu Guibin , Huang Weimin

Importance: Coronary algorithm for cardiac sub structures and prospective real-time surveillance of cardiac dose exposure. Methods: Retro and prospective study to validate AI auto-segmentation. A 3D UNet was trained on 560 thoracic CT scans…

Deep Neural Networks (DNNs) have advanced the state-of-the-art in a variety of machine learning tasks and are deployed in increasing numbers of products and services. However, the computational requirements of training and evaluating…

Neural and Evolutionary Computing · Computer Science 2017-04-06 Sanjay Ganapathy , Swagath Venkataramani , Balaraman Ravindran , Anand Raghunathan

Chronic diseases such as diabetes are quite prevalent in the world and are responsible for a significant number of deaths per year. In addition, treatments for such chronic diseases account for a high healthcare cost. However, research has…

Machine Learning · Computer Science 2021-09-07 Asish Satpathy , Satyajit Behari

Chronic diseases are long-lasting conditions that require lifelong medical attention. Using big EMR data, we have developed early disease risk prediction models for five common chronic diseases: diabetes, hypertension, CKD, COPD, and…

Machine Learning · Computer Science 2026-03-13 Shaheer Ahmad Khan , Muhammad Usamah Shahid , Muddassar Farooq

Hospital readmission among patients with chronic heart failure (HF) is a major clinical and economic burden. Dynamic prediction models that leverage longitudinal biomarkers may improve risk stratification over traditional static models.…

Applications · Statistics 2026-01-22 Rebecca Farina , Francois Mercier , Christian Wohlfart , Serge Masson , Silvia Metelli

Hyperkalemia is a potentially life-threatening condition that can lead to fatal arrhythmias. Early identification of high risk patients can inform clinical care to mitigate the risk. While hyperkalemia is often a complication of acute…

Machine Learning · Computer Science 2021-01-28 Gloria Hyunjung Kwak , Christina Chen , Lowell Ling , Erina Ghosh , Leo Anthony Celi , Pan Hui

In many clinical trials studying neurodegenerative diseases such as Parkinson's disease (PD), multiple longitudinal outcomes are collected to fully explore the multidimensional impairment caused by this disease. If the outcomes deteriorate…

Applications · Statistics 2017-05-18 Jue Wang , Sheng Luo , Liang Li

Clinical diagnostic guidelines outline the key questions to answer to reach a diagnosis. Inspired by guidelines, we aim to develop a model that learns from electronic health records to determine the optimal sequence of actions for accurate…

Sepsis-induced acute respiratory failure (ARF) is a serious complication with a poor prognosis. This paper presents a deep representation learningbased phenotyping method to identify distinct groups of clinical trajectories of septic…

Signal Processing · Electrical Eng. & Systems 2024-05-07 Alan Wu , Tilendra Choudhary , Pulakesh Upadhyaya , Ayman Ali , Philip Yang , Rishikesan Kamaleswaran

As COVID-19 transitions into an endemic disease that remains constantly present in the population at a stable level, monitoring its prevalence without invasive measures becomes increasingly important. In this paper, we present a deep neural…

Quantitative Methods · Quantitative Biology 2025-12-02 Yifei Chen , Eric Liang

The kidney exchange problem (KEP) is to find a constellation of exchanges that maximizes the number of transplants that can be carried out for a set of pairs of patients with kidney disease and their incompatible donors. Recently, this…

Cryptography and Security · Computer Science 2023-10-24 Malte Breuer , Pascal Hein , Leonardo Pompe , Ben Temme , Ulrike Meyer , Susanne Wetzel

In breast cancer, neoadjuvant chemotherapy (NAC) provides a standard treatment option for patients who have locally advanced cancer and some large operable tumors. A patient will have better prognosis when he has achieved a pathological…

Medical Physics · Physics 2024-11-12 Yongquan Yang , Fengling Li , Yani Wei , Yuanyuan Zhao , Jing Fu , Xiuli Xiao , Hong Bu

Celiac disease prevalence and diagnosis have increased substantially in recent years. The current gold standard for celiac disease confirmation is visual examination of duodenal mucosal biopsies. An accurate computer-aided biopsy analysis…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Jason W. Wei , Jerry W. Wei , Christopher R. Jackson , Bing Ren , Arief A. Suriawinata , Saeed Hassanpour

Classical radiomic features are designed to quantify image appearance and intensity patterns. Compared with end-to-end deep learning (DL) models trained for disease classification, radiomics pipelines with low-dimensional parametric…

Computer Vision and Pattern Recognition · Computer Science 2026-03-04 Yaxi Chen , Simin Ni , Jingjing Zhang , Shaheer U. Saeed , Yipei Wang , Aleksandra Ivanova , Rikin Hargunani , Chaozong Liu , Jie Huang , Yipeng Hu

Acute brain dysfunctions (ABD), which include coma and delirium, are prevalent in the ICU, especially among older patients. The current approach in manual assessment of ABD by care providers may be sporadic and subjective. Hence, there…