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Predicting the incidence of complex chronic conditions such as heart failure is challenging. Deep learning models applied to rich electronic health records may improve prediction but remain unexplainable hampering their wider use in medical…

Purpose: This study evaluated the out-of-domain performance and generalization capabilities of automated medical image segmentation models, with a particular focus on adaptation to new image acquisitions and disease type. Materials:…

Image and Video Processing · Electrical Eng. & Systems 2023-07-28 Timothy L. Kline , Sumana Ramanathan , Harrison C. Gottlich , Panagiotis Korfiatis , Adriana V. Gregory

Background:Chronic kidney disease is one of the most prevalent non-communicable health issues globally, and high body mass index plays a significant role in the onset and progression of chronic kidney disease. Methods: Data on the disease…

Populations and Evolution · Quantitative Biology 2025-08-01 Yu Chen , Guangxi Wu

Recent advances in deep learning (DL) have prompted the development of high-performing early warning score (EWS) systems, predicting clinical deteriorations such as acute kidney injury, acute myocardial infarction, or circulatory failure.…

Machine Learning · Computer Science 2025-02-05 Yuxiao Cheng , Xinxin Song , Ziqian Wang , Qin Zhong , Kunlun He , Jinli Suo

Accurate cell nuclei segmentation is critical for downstream tasks in kidney pathology and remains a major challenge due to the morphological diversity and imaging variability of renal tissues. While our prior work has evaluated…

Kidney stones are a common and debilitating health issue, and genetic factors play a crucial role in determining susceptibility. While Genome-Wide Association Studies (GWAS) have identified numerous single nucleotide polymorphisms (SNPs)…

Genomics · Quantitative Biology 2024-12-24 Amr Salem , Anirban Mondal

Predictive modeling with electronic health record (EHR) data is anticipated to drive personalized medicine and improve healthcare quality. Constructing predictive statistical models typically requires extraction of curated predictor…

Ultrasound (US) is widely accessible and radiation-free but has a steep learning curve due to its dynamic nature and non-standard imaging planes. Additionally, the constant need to shift focus between the US screen and the patient poses a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Gijs Luijten , Roberto Maria Scardigno , Lisle Faray de Paiva , Peter Hoyer , Jens Kleesiek , Domenico Buongiorno , Vitoantonio Bevilacqua , Jan Egger

Accurate prediction of medical conditions with straight past clinical evidence is a long-sought topic in the medical management and health insurance field. Although great progress has been made with machine learning algorithms, the medical…

Machine Learning · Computer Science 2024-12-06 Dongping Fang , Lian Duan , Xiaojing Yuan , Allyn Klunder , Kevin Tan , Suiting Cao , Yeqing Ji , Mike Xu

Several algorithms for learning the structure of dynamic Bayesian networks (DBNs) require an a priori ordering of variables, which influences the determined graph topology. However, it is often unclear how to determine this order if feature…

Robust forecasting of the future anatomical changes inflicted by an ongoing disease is an extremely challenging task that is out of grasp even for experienced healthcare professionals. Such a capability, however, is of great importance…

Computer Vision and Pattern Recognition · Computer Science 2022-11-09 Dmitrii Lachinov , Arunava Chakravarty , Christoph Grechenig , Ursula Schmidt-Erfurth , Hrvoje Bogunovic

Background: The COVID-19 pandemic has had a profound impact on health, everyday life and economics around the world. An important complication that can arise in connection with a COVID-19 infection is acute kidney injury. A recent…

In response to the pressing challenge of kidney allocation, characterized by growing demands for organs, this research sets out to develop a data-driven solution to this problem, which also incorporates stakeholder values. The primary…

This study investigates the relationship between longitudinal serum creatinine measurements and the risk of adverse kidney outcomes in paediatric patients with auto-immune disorders at Great Ormond Street Hospital for Children NHS…

Early identification of patients at risk for clinical deterioration in the intensive care unit (ICU) remains a critical challenge. Delayed recognition of impending adverse events, including mortality, vasopressor initiation, and mechanical…

Machine Learning · Computer Science 2026-03-17 Binesh Sadanandan

The COVID-19 pandemic has had far-reaching implications for global public health. As we continue to grapple with its consequences, it becomes increasingly clear that post-COVID-19 complications are a significant concern. Among these…

To evaluate the translational capabilities of foundation models, we develop a pathological concept learning approach focused on kidney cancer. By leveraging TNM staging guidelines and pathology reports, we build comprehensive pathological…

Artificial Intelligence · Computer Science 2025-10-01 Shangqi Gao , Sihan Wang , Yibo Gao , Boming Wang , Xiahai Zhuang , Anne Warren , Grant Stewart , James Jones , Mireia Crispin-Ortuzar

Background: Clinical diagnosis is typically reached by following a series of steps recommended by guidelines authored by colleges of experts. Accordingly, guidelines play a crucial role in rationalizing clinical decisions but suffer from…

Machine Learning · Computer Science 2024-04-10 Lillian Muyama , Antoine Neuraz , Adrien Coulet

Adverse Drug Events (ADEs), harmful medication effects, pose significant healthcare challenges, impacting patient safety and costs. This study evaluates automatic Knowledge-Driven Feature Engineering (aKDFE) for improved ADE prediction from…

Machine Learning · Computer Science 2025-05-29 Olof Björneld , Tora Hammar , Daniel Nilsson , Alisa Lincke , Welf Löwe

Fall risk prediction among hospitalized patients is a critical aspect of patient safety in clinical settings, and accurate models can help prevent adverse events. The Hester Davis Score (HDS) is commonly used to assess fall risk, with…

Machine Learning · Computer Science 2025-01-14 Hojjat Salehinejad , Ricky Rojas , Kingsley Iheasirim , Mohammed Yousufuddin , Bijan Borah
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