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Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner,…

Machine Learning · Computer Science 2025-08-12 Yiran Huang , Amirhossein Nouranizadeh , Christine Ahrends , Mengjia Xu

Objective: This paper presents an Alzheimer's disease (AD) detection method based on learning structural similarity between Magnetic Resonance Images (MRIs) and representing this similarity as a graph. Methods: We construct the similarity…

Computer Vision and Pattern Recognition · Computer Science 2021-03-01 Kuo Yang , Emad A. Mohammed , Behrouz H. Far

Recent contrastive methods show significant improvement in self-supervised learning in several domains. In particular, contrastive methods are most effective where data augmentation can be easily constructed e.g. in computer vision.…

Machine Learning · Computer Science 2021-12-09 Konstantinos Kallidromitis , Denis Gudovskiy , Kazuki Kozuka , Iku Ohama , Luca Rigazio

We propose a novel benchmarking methodology for graph neural networks (GNNs) based on the graph alignment problem, a combinatorial optimization task that generalizes graph isomorphism by aligning two unlabeled graphs to maximize overlapping…

Machine Learning · Computer Science 2025-05-20 Adrien Lagesse , Marc Lelarge

In applications of graphical models, we typically have more information than just the samples themselves. A prime example is the estimation of brain connectivity networks based on fMRI data, where in addition to the samples themselves, the…

Machine Learning · Statistics 2017-04-21 Yunqi Bu , Johannes Lederer

Functional connectivity analysis is an important tool for characterizing interactions among brain regions, particularly in studies of neurodegenerative disorders such as Alzheimer's disease (AD). Gaussian graphical models (GGMs) provide a…

Methodology · Statistics 2026-04-14 Panpan Zhang , Shiying Xiao , W. Hudson Robb , Dandan Liu , Angela L. Jefferson , Jun Yan

Structural magnetic resonance imaging (sMRI) combined with deep learning has achieved remarkable progress in the prediction and diagnosis of Alzheimer's disease (AD). Existing studies have used CNN and transformer to build a well-performing…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Zheng Yang , Yanteng Zhang , Xupeng Kou , Yang Liu , Chao Ren

Neural network approaches are machine learning methods that are widely used in various domains, such as healthcare and cybersecurity. Neural networks are especially renowned for their ability to deal with image datasets. During the training…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Mst Shapna Akter , Hossain Shahriar , Alfredo Cuzzocrea

The global functional brain network (graph) is more suitable for characterizing brain states than local analysis of the connectivity of brain regions. Therefore, graph-theoretic approaches are the natural methods to study the brain.…

Magnetic resonance imaging (MRI) is an invaluable tool for clinical and research applications. Yet, variations in scanners and acquisition parameters cause inconsistencies in image contrast, hindering data comparability and reproducibility…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Daniel Scholz , Ayhan Can Erdur , Robbie Holland , Viktoria Ehm , Jan C. Peeken , Benedikt Wiestler , Daniel Rueckert

Graph neural network (GNN) is a popular tool to learn the lower-dimensional representation of a graph. It facilitates the applicability of machine learning tasks on graphs by incorporating domain-specific features. There are various options…

Machine Learning · Computer Science 2020-08-21 Md. Khaledur Rahman

While tokenized graph Transformers have demonstrated strong performance in node classification tasks, their reliance on a limited subset of nodes with high similarity scores for constructing token sequences overlooks valuable information…

Machine Learning · Computer Science 2025-02-18 Jinsong Chen , Hanpeng Liu , John E. Hopcroft , Kun He

This paper presents a methodology for image classification using Graph Neural Network (GNN) models. We transform the input images into region adjacency graphs (RAGs), in which regions are superpixels and edges connect neighboring…

Machine Learning · Computer Science 2020-11-17 Pedro H. C. Avelar , Anderson R. Tavares , Thiago L. T. da Silveira , Cláudio R. Jung , Luís C. Lamb

Although self-supervised learning enables us to bootstrap the training by exploiting unlabeled data, the generic self-supervised methods for natural images do not sufficiently incorporate the context. For medical images, a desirable method…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Li Sun , Ke Yu , Kayhan Batmanghelich

Significant progress has been made using fMRI to characterize the brain changes that occur in ASD, a complex neuro-developmental disorder. However, due to the high dimensionality and low signal-to-noise ratio of fMRI, embedding informative…

Image and Video Processing · Electrical Eng. & Systems 2019-08-15 Xiaoxiao Li , Nicha C. Dvornek , Juntang Zhuang , Pamela Ventola , James Duncan

Functional magnetic resonance imaging (fMRI) data is characterized by its complexity and high--dimensionality, encompassing signals from various regions of interests (ROIs) that exhibit intricate correlations. Analyzing fMRI data directly…

Applications · Statistics 2024-01-18 Yeseul Jeon , Jeong-Jae Kim , SuMin Yu , Junggu Choi , Sanghoon Han

Understanding disease similarity is critical for advancing diagnostics, drug discovery, and personalized treatment strategies. We present PhenoGnet, a novel graph-based contrastive learning framework designed to predict disease similarity…

Genomics · Quantitative Biology 2025-09-18 Ranga Baminiwatte , Kazi Jewel Rana , Aaron J. Masino

Objective: Multi-modal functional magnetic resonance imaging (fMRI) can be used to make predictions about individual behavioral and cognitive traits based on brain connectivity networks. Methods: To take advantage of complementary…

Machine Learning · Computer Science 2024-08-27 Gang Qu , Li Xiao , Wenxing Hu , Kun Zhang , Vince D. Calhoun , Yu-Ping Wang

We study self-supervised learning on graphs using contrastive methods. A general scheme of prior methods is to optimize two-view representations of input graphs. In many studies, a single graph-level representation is computed as one of the…

Machine Learning · Computer Science 2021-07-22 Xinyi Xu , Cheng Deng , Yaochen Xie , Shuiwang Ji

Inspired by the recent success of self-supervised methods applied on images, self-supervised learning on graph structured data has seen rapid growth especially centered on augmentation-based contrastive methods. However, we argue that…

Machine Learning · Computer Science 2021-12-08 Namkyeong Lee , Junseok Lee , Chanyoung Park
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