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Existing Medical Large Vision-Language Models (Med-LVLMs), encapsulating extensive medical knowledge, demonstrate excellent capabilities in understanding medical images. However, there remain challenges in visual localization in medical…

Computation and Language · Computer Science 2025-06-03 Yucheng Zhou , Lingran Song , Jianbing Shen

Large Language Models (LLMs) have demonstrated exceptional proficiency in text understanding and embedding tasks. However, their potential in multimodal representation, particularly for item-to-item (I2I) recommendations, remains…

Information Retrieval · Computer Science 2025-01-22 Chao Zhang , Haoxin Zhang , Shiwei Wu , Di Wu , Tong Xu , Xiangyu Zhao , Yan Gao , Yao Hu , Enhong Chen

According to the 2021 World Health Organization (WHO) Classification scheme for gliomas, glioma segmentation is a very important basis for diagnosis and genotype prediction. In general, 3D multimodal brain MRI is an effective diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Xiaoyu Shi , Shurong Chai , Yinhao Li , Jingliang Cheng , Jie Bai , Guohua Zhao , Yen-Wei Chen

Multimodal magnetic resonance imaging (MRI) constitutes the first line of investigation for clinicians in the care of brain tumors, providing crucial insights for surgery planning, treatment monitoring, and biomarker identification.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Lucas Robinet , Ahmad Berjaoui , Elizabeth Cohen-Jonathan Moyal

Continual learning is essential for adapting models to new tasks while retaining previously acquired knowledge. While existing approaches predominantly focus on uni-modal data, multi-modal learning offers substantial benefits by utilizing…

Machine Learning · Computer Science 2025-11-11 Evelyn Chee , Wynne Hsu , Mong Li Lee

The core role of medical images in disease diagnosis makes their quality directly affect the accuracy of clinical judgment. However, due to factors such as low-dose scanning, equipment limitations and imaging artifacts, medical images are…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Tao Tang , Chengxu Yang

Integrating brain imaging data with clinical reports offers a valuable opportunity to leverage complementary multimodal information for more effective and timely diagnosis in practical clinical settings. This approach has gained significant…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Jing Zhang , Xiaowei Yu , Minheng Chen , Lu Zhang , Tong Chen , Yan Zhuang , Chao Cao , Yanjun Lyu , Li Su , Tianming Liu , Dajiang Zhu

We present MM1.5, a new family of multimodal large language models (MLLMs) designed to enhance capabilities in text-rich image understanding, visual referring and grounding, and multi-image reasoning. Building upon the MM1 architecture,…

Gaining insights into the structural and functional mechanisms of the brain has been a longstanding focus in neuroscience research, particularly in the context of understanding and treating neuropsychiatric disorders such as Schizophrenia…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Badhan Mazumder , Lei Wu , Vince D. Calhoun , Dong Hye Ye

The Contrastive Language-Image Pre-training (CLIP) framework has become a widely used approach for multimodal representation learning, particularly in image-text retrieval and clustering. However, its efficacy is constrained by three key…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Tiancheng Gu , Kaicheng Yang , Ziyong Feng , Xingjun Wang , Yanzhao Zhang , Dingkun Long , Yingda Chen , Weidong Cai , Jiankang Deng

This paper demonstrates that a progressively aligned language model can effectively bridge frozen vision encoders and large language models (LLMs). While the fundamental architecture and pre-training methods of vision encoders and LLMs have…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Junfei Xiao , Zheng Xu , Alan Yuille , Shen Yan , Boyu Wang

In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 Hongwei Li , Timo Loehr , Anjany Sekuboyina , Jianguo Zhang , Benedikt Wiestler , Bjoern Menze

Automated diagnosis of Alzheimer Disease(AD) from brain imaging, such as magnetic resonance imaging (MRI), has become increasingly important and has attracted the community to contribute many deep learning methods. However, many of these…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Yifeng Wang , Ke Chen , Haohan Wang

This paper proposes LayoutLLM, a more flexible document analysis method for understanding imaged documents. Visually Rich Document Understanding tasks, such as document image classification and information extraction, have gained…

Computation and Language · Computer Science 2024-03-22 Masato Fujitake

Data is one of the essential ingredients to power deep learning research. Small datasets, especially specific to medical institutes, bring challenges to deep learning training stage. This work aims to develop a practical deep multimodal…

Machine Learning · Computer Science 2019-02-26 Faik Aydin , Maggie Zhang , Michelle Ananda-Rajah , Gholamreza Haffari

Large-scale contrastive vision-language pre-training has shown significant progress in visual representation learning. Unlike traditional visual systems trained by a fixed set of discrete labels, a new paradigm was introduced in…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Peng Gao , Shijie Geng , Renrui Zhang , Teli Ma , Rongyao Fang , Yongfeng Zhang , Hongsheng Li , Yu Qiao

Prompt learning has demonstrated impressive efficacy in the fine-tuning of multimodal large models to a wide range of downstream tasks. Nonetheless, applying existing prompt learning methods for the diagnosis of neurological disorder still…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Liang Peng , Songyue Cai , Zongqian Wu , Huifang Shang , Xiaofeng Zhu , Xiaoxiao Li

In the past five years, research has shifted from traditional Machine Learning (ML) and Deep Learning (DL) approaches to leveraging Large Language Models (LLMs) , including multimodality, for data augmentation to enhance generalization, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Ranjan Sapkota , Shaina Raza , Maged Shoman , Achyut Paudel , Manoj Karkee

Currently intelligent diagnosis systems lack the ability of continually learning to diagnose new diseases once deployed, under the condition of preserving old disease knowledge. In particular, updating an intelligent diagnosis system with…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Wentao Zhang , Yujun Huang , Tong Zhang , Qingsong Zou , Wei-Shi Zheng , Ruixuan Wang

Understanding the internal mechanisms by which multi-modal large language models (LLMs) interpret different modalities and integrate cross-modal representations is becoming increasingly critical for continuous improvements in both academia…

Computation and Language · Computer Science 2024-06-12 Haowen Pan , Yixin Cao , Xiaozhi Wang , Xun Yang , Meng Wang