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Depression is one of the most prevalent mental health disorders globally. In recent years, multi-modal data, such as speech, video, and transcripts, has been increasingly used to develop AI-assisted depression assessment systems. Large…

The advent of Large Language Models (LLMs) has significantly reshaped the trajectory of the AI revolution. Nevertheless, these LLMs exhibit a notable limitation, as they are primarily adept at processing textual information. To address this…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Akash Ghosh , Arkadeep Acharya , Sriparna Saha , Vinija Jain , Aman Chadha

We propose ControlMLLM++, a novel test-time adaptation framework that injects learnable visual prompts into frozen multimodal large language models (MLLMs) to enable fine-grained region-based visual reasoning without any model retraining or…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Mingrui Wu , Hao Chen , Jiayi Ji , Xiaoshuai Sun , Zhiyuan Liu , Liujuan Cao , Ming-Ming Cheng , Rongrong Ji

While large language models have facilitated breakthroughs in many applications of artificial intelligence, their inherent largeness makes them computationally expensive and challenging to deploy in resource-constrained settings. In this…

Large Multimodal Models (LMMs), or Vision-Language Models (VLMs), have shown impressive capabilities in a wide range of visual tasks. However, they often struggle with fine-grained visual reasoning, failing to identify domain-specific…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Yucheng Shi , Quanzheng Li , Jin Sun , Xiang Li , Ninghao Liu

Effective patient-provider communication is difficult to assess at scale. We examine whether large language models (LLMs) can track 20 social behaviors from clinical transcripts without fine-tuning. Across three model families and multiple…

Computation and Language · Computer Science 2026-05-14 Manas Satish Bedmutha , Feng Chen , Andrea Hartzler , Trevor Cohen , Nadir Weibel

In anomaly detection, methods based on large language models (LLMs) can incorporate expert knowledge by reading professional document, while task-specific small models excel at extracting normal data patterns and detecting value…

Artificial Intelligence · Computer Science 2026-03-31 Feiyi Chen , Leilei Zhang , Guansong Pang , Roger Zimmermann , Shuiguang Deng

Recent advancements in Multimodal Large Language Models (MLLMs) have demonstrated remarkable progress in visual understanding. This impressive leap raises a compelling question: how can language models, initially trained solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Jing Bi , Junjia Guo , Yunlong Tang , Lianggong Bruce Wen , Zhang Liu , Chenliang Xu

Multimodal information retrieval (MMIR) has gained attention for its flexibility in handling text, images, or mixed queries and candidates. Recent breakthroughs in multimodal large language models (MLLMs) boost MMIR performance by…

Information Retrieval · Computer Science 2026-02-27 Dawei Su , Dongsheng Wang

Large language models (LLMs) are increasingly being used as decision aids. However, users have diverse values and preferences that can affect their decision-making, which requires novel methods for LLM alignment and personalization.…

Computation and Language · Computer Science 2025-07-15 Bharadwaj Ravichandran , David Joy , Paul Elliott , Brian Hu , Jadie Adams , Christopher Funk , Emily Veenhuis , Anthony Hoogs , Arslan Basharat

Microwell microfluidics has been utilized for single-cell analysis to reveal heterogeneity in gene expression, signaling pathways, and phenotypic responses for identifying rare cell types, understanding disease progression, and developing…

Neurons and Cognition · Quantitative Biology 2025-10-17 Dinh-Nguyen Nguyen , Sadia Shakil , Raymond Kai-Yu Tong , Ngoc-Duy Dinh

Multimodal Large Language Models (MLLMs) have showcased impressive skills in tasks related to visual understanding and reasoning. Yet, their widespread application faces obstacles due to the high computational demands during both the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Minjie Zhu , Yichen Zhu , Xin Liu , Ning Liu , Zhiyuan Xu , Chaomin Shen , Yaxin Peng , Zhicai Ou , Feifei Feng , Jian Tang

Large language models (LLMs) face significant challenges in specialized domains like telecommunication (Telecom) due to technical complexity, specialized terminology, and rapidly evolving knowledge. Traditional methods, such as scaling…

Information Theory · Computer Science 2025-06-03 Xinquan Wang , Fenghao Zhu , Chongwen Huang , Zhaohui Yang , Zhaoyang Zhang , Sami Muhaidat , Chau Yuen , Mérouane Debbah

Large Language Models (LLMs) have demonstrated remarkable performance across various natural language tasks, marking significant strides towards general artificial intelligence. While general artificial intelligence is leveraged by…

Computation and Language · Computer Science 2023-10-31 Yizhe Yang , Huashan Sun , Jiawei Li , Runheng Liu , Yinghao Li , Yuhang Liu , Heyan Huang , Yang Gao

The validity of medical studies based on real-world clinical data, such as observational studies, depends on critical assumptions necessary for drawing causal conclusions about medical interventions. Many published studies are flawed…

Artificial Intelligence · Computer Science 2024-07-30 Ahmed Alaa , Rachael V. Phillips , Emre Kıcıman , Laura B. Balzer , Mark van der Laan , Maya Petersen

Connecting text and visual modalities plays an essential role in generative intelligence. For this reason, inspired by the success of large language models, significant research efforts are being devoted to the development of Multimodal…

Computer Vision and Pattern Recognition · Computer Science 2024-06-07 Davide Caffagni , Federico Cocchi , Luca Barsellotti , Nicholas Moratelli , Sara Sarto , Lorenzo Baraldi , Lorenzo Baraldi , Marcella Cornia , Rita Cucchiara

Large language models (LLMs) have shown exceptional performance on a variety of natural language tasks. Yet, their capabilities for HTML understanding -- i.e., parsing the raw HTML of a webpage, with applications to automation of web-based…

The classification of genetic variants, particularly Variants of Uncertain Significance (VUS), poses a significant challenge in clinical genetics and precision medicine. Large Language Models (LLMs) have emerged as transformative tools in…

Multimodal Large Language Models (MLLMs) are gaining increasing popularity in both academia and industry due to their remarkable performance in various applications such as visual question answering, visual perception, understanding, and…

Computation and Language · Computer Science 2024-09-09 Jian Li , Weiheng Lu , Hao Fei , Meng Luo , Ming Dai , Min Xia , Yizhang Jin , Zhenye Gan , Ding Qi , Chaoyou Fu , Ying Tai , Wankou Yang , Yabiao Wang , Chengjie Wang

Clinical trial matching is a key process in health delivery and discovery. In practice, it is plagued by overwhelming unstructured data and unscalable manual processing. In this paper, we conduct a systematic study on scaling clinical trial…

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