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Related papers: Coding for Strand Breaks in Composite DNA

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Erasure coding techniques are getting integrated in networked distributed storage systems as a way to provide fault-tolerance at the cost of less storage overhead than traditional replication. Redundancy is maintained over time through…

Distributed, Parallel, and Cluster Computing · Computer Science 2012-06-12 Lluis Pamies-Juarez , Frédérique Oggier , Anwitaman Datta

DNA storage has matured from concept to practical stage, yet its integration with neural compression pipelines remains inefficient. Early DNA encoders applied redundancy-heavy constraint layers atop raw binary data - workable but primitive.…

Machine Learning · Computer Science 2026-02-09 Cihan Ruan , Lebin Zhou , Rongduo Han , Linyi Han , Bingqing Zhao , Chenchen Zhu , Wei Jiang , Wei Wang , Nam Ling

Noisy shuffling channels capture the main characteristics of DNA storage systems where distinct segments of data are received out of order, after being corrupted by substitution errors. For realistic schemes with short-length segments,…

Information Theory · Computer Science 2024-10-07 Javad Haghighat , Tolga M. Duman

Due to its longevity and enormous information density, DNA is an attractive medium for archival storage. In this work, we study the fundamental limits and trade-offs of DNA-based storage systems by introducing a new channel model, which we…

Information Theory · Computer Science 2020-01-20 Ilan Shomorony , Reinhard Heckel

Genetic information is stored in a linear sequence of base-pairs; however, thermal fluctuations and complex DNA conformations such as folds and loops make it challenging to order genomic material for in vitro analysis. In this work, we…

Biological data mainly comprises of Deoxyribonucleic acid (DNA) and protein sequences. These are the biomolecules which are present in all cells of human beings. Due to the self-replicating property of DNA, it is a key constitute of genetic…

Other Quantitative Biology · Quantitative Biology 2020-06-04 Shakeela Bibi , Javed Iqbal , Adnan Iftekhar , Mir Hassan

Over the past years, the ever-growing trend on data storage demand, more specifically for "cold" data (rarely accessed data), has motivated research for alternative systems of data storage. Because of its biochemical characteristics,…

Machine Learning · Computer Science 2022-03-21 Xavier Pic , Marc Antonini

We propose a novel coding scheme for DNA-based storage systems, called the shift-interleave (SI) coding, designed to correct insertion, deletion, and substitution (IDS) errors, as well as sequence losses. The SI coding scheme employs…

Information Theory · Computer Science 2024-01-29 Ryo Shibata , Haruhiko Kaneko

The exponentially increasing demand for data storage has been facing more and more challenges during the past years. The energy costs that it represents are also increasing, and the availability of the storage hardware is not able to follow…

Image and Video Processing · Electrical Eng. & Systems 2022-03-21 Xavier Pic , Marc Antonini

Over the past years, the ever-growing trend on data storage demand, more specifically for "cold" data (rarely accessed data), has motivated research for alternative systems of data storage. Because of its biochemical characteristics,…

Image and Video Processing · Electrical Eng. & Systems 2023-06-23 Xavier Pic , Eva Gil San Antonio , Melpomeni Dimopoulou , Marc Antonini

Because of its high data density and longevity, DNA is emerging as a promising candidate for satisfying increasing data storage needs. Compared to conventional storage media, however, data stored in DNA is subject to a wider range of errors…

Information Theory · Computer Science 2020-08-20 Yuanyuan Tang , Farzad Farnoud

We present a finite blocklength performance bound for a DNA storage channel with insertions, deletions, and substitutions. The considered bound -- the dependency testing (DT) bound, introduced by Polyanskiy et al. in 2010 -- provides an…

Information Theory · Computer Science 2023-08-07 Issam Maarouf , Gianluigi Liva , Eirik Rosnes , Alexandre Graell i Amat

Erasure coding is a storage-efficient alternative to replication for achieving reliable data backup in distributed storage systems. During the storage process, traditional erasure codes require a unique source node to create and upload all…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-03-19 Lluis Pamies-Juarez , Anwitaman Datta , Frédérique Oggier

To make DNA a suitable medium for archival data storage, it is essential to consider the decay process of the strands observed in DNA storage systems. This paper studies the decay process as a probabilistic noisy torn paper channel (TPC),…

Information Theory · Computer Science 2026-01-19 Frederik Walter , Maria Abu-Sini , Nils Weinhardt , Antonia Wachter-Zeh

DNA storage is now being considered as a new archival storage method for its durability and high information density, but still facing some challenges like high costs and low throughput. By reducing sequencing sample size for decoding…

Information Theory · Computer Science 2025-04-22 Ruiying Cao , Xin Chen

Over the past years, the ever-growing trend on data storage demand, more specifically for "cold" data (i.e. rarely accessed), has motivated research for alternative systems of data storage. Because of its biochemical characteristics,…

Image and Video Processing · Electrical Eng. & Systems 2023-09-15 Xavier Pic , Melpomeni Dimopoulou , Eva Gil San Antonio , Marc Antonini

Large pools of synthetic DNA molecules have been recently used to reliably store significant volumes of digital data. While DNA as a storage medium has enormous potential because of its high storage density, its practical use is currently…

Data Structures and Algorithms · Computer Science 2021-02-25 Konstantin Makarychev , Miklos Z. Racz , Cyrus Rashtchian , Sergey Yekhanin

Recent experiments have demonstrated the feasibility of storing digital information in macromolecules such as DNA and protein. However, the DNA storage channel is prone to errors such as deletions, insertions, and substitutions. During the…

Information Theory · Computer Science 2024-10-22 Aryan Abbasian , Mahtab Mirmohseni , Masoumeh Nasiri Kenari

This work presents a theoretical analysis of the probability of successfully retrieving data encoded with MDS codes (e.g., Reed-Solomon codes) in DNA storage systems. We study this probability under independent and identically distributed…

Information Theory · Computer Science 2026-05-08 Serge Kas Hanna

Standard decoding approaches for convolutional codes, such as the Viterbi and BCJR algorithms, entail significant complexity when correcting synchronization errors. The situation worsens when multiple received sequences should be jointly…

Information Theory · Computer Science 2024-10-10 Anisha Banerjee , Lorenz Welter , Alexandre Graell i Amat , Antonia Wachter-Zeh , Eirik Rosnes