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Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

Question answering is a task that answers factoid questions using a large collection of documents. It aims to provide precise answers in response to the user's questions in natural language. Question answering relies on efficient passage…

Computation and Language · Computer Science 2023-08-09 Shashank Gupta

Although large language models (LLMs) often produce impressive outputs, it remains unclear how they perform in real-world scenarios requiring strong reasoning skills and expert domain knowledge. We set out to investigate whether close- and…

Computation and Language · Computer Science 2023-12-27 Valentin Liévin , Christoffer Egeberg Hother , Andreas Geert Motzfeldt , Ole Winther

We introduce Biomed-Enriched, a biomedical text dataset constructed from PubMed via a two-stage annotation process. In the first stage, a large language model annotates 400K paragraphs from PubMed scientific articles, assigning scores for…

Computation and Language · Computer Science 2025-06-26 Rian Touchent , Nathan Godey , Eric de la Clergerie

Recent researches of large language models(LLM), which is pre-trained on massive general-purpose corpora, have achieved breakthroughs in responding human queries. However, these methods face challenges including limited data insufficiency…

Computation and Language · Computer Science 2025-01-07 Yiming Zhang , Zheng Chang , Wentao Cai , MengXing Ren , Kang Yuan , Yining Sun , Zenghui Ding

Large Language Models (LLMs) have gained significant attention in the medical domain for their human-level capabilities, leading to increased efforts to explore their potential in various healthcare applications. However, despite such a…

Artificial Intelligence · Computer Science 2024-10-25 Yifan Yang , Qiao Jin , Qingqing Zhu , Zhizheng Wang , Francisco Erramuspe Álvarez , Nicholas Wan , Benjamin Hou , Zhiyong Lu

LoRA (Low-Rank Adaptation) has emerged as a preferred method for efficiently adapting Large Language Models (LLMs) with remarkable simplicity and efficacy. This note extends the original LoRA paper by offering new perspectives that were not…

Machine Learning · Computer Science 2024-04-09 Vlad Fomenko , Han Yu , Jongho Lee , Stanley Hsieh , Weizhu Chen

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

Computation and Language · Computer Science 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

In the era of digital healthcare, the huge volumes of textual information generated every day in hospitals constitute an essential but underused asset that could be exploited with task-specific, fine-tuned biomedical language representation…

Computation and Language · Computer Science 2023-07-12 Tommaso Mario Buonocore , Claudio Crema , Alberto Redolfi , Riccardo Bellazzi , Enea Parimbelli

We explore how continued pre-training on domain-specific corpora influences large language models, revealing that training on the raw corpora endows the model with domain knowledge, but drastically hurts its prompting ability for question…

Computation and Language · Computer Science 2024-07-26 Daixuan Cheng , Shaohan Huang , Furu Wei

Tools to explore scientific literature are essential for scientists, especially in biomedicine, where about a million new papers are published every year. Many such tools provide users the ability to search for specific entities (e.g.…

Computation and Language · Computer Science 2021-07-05 Sunil Mohan , Rico Angell , Nick Monath , Andrew McCallum

The transcription of medical monologues, especially those containing a high density of specialized terminology and delivered with a distinct accent, presents a significant challenge for existing automated systems. This paper introduces a…

Computation and Language · Computer Science 2024-10-08 Jiafeng Li , Yanda Mu

In the digital age, people often turn to the Internet in search of medical advice and recommendations. With the increasing volume of online content, it has become difficult to distinguish reliable sources from misleading information.…

Computation and Language · Computer Science 2025-09-03 Juraj Vladika , Florian Matthes

Scientific progress is driven by the deliberate articulation of what remains unknown. This study investigates the ability of large language models (LLMs) to identify research knowledge gaps in the biomedical literature. We define two…

Computation and Language · Computer Science 2025-10-30 Nourah M Salem , Elizabeth White , Michael Bada , Lawrence Hunter

Personalized medicine remains a major challenge for scientists. The rapid growth of Machine learning and Deep learning has made them a feasible al- ternative for predicting the most appropriate therapy for individual patients. However, the…

Machine Learning · Computer Science 2025-06-10 Antonio Jesús Banegas-Luna , Horacio Pérez-Sánchez

Understanding medical texts presents significant challenges due to complex terminology and context-specific language. This paper introduces Medalyze, an AI-powered application designed to enhance the comprehension of medical texts using…

Computation and Language · Computer Science 2025-05-26 Van-Tinh Nguyen , Hoang-Duong Pham , Thanh-Hai To , Cong-Tuan Hung Do , Thi-Thu-Trang Dong , Vu-Trung Duong Le , Van-Phuc Hoang

Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Large Language Models…

Computation and Language · Computer Science 2024-03-01 Fergus Imrie , Paulius Rauba , Mihaela van der Schaar

Large Language Models (LLMs), such as the LLaMA model, have demonstrated their effectiveness in various general-domain natural language processing (NLP) tasks. Nevertheless, LLMs have not yet performed optimally in biomedical domain tasks…

Computation and Language · Computer Science 2023-04-17 Haochun Wang , Chi Liu , Nuwa Xi , Zewen Qiang , Sendong Zhao , Bing Qin , Ting Liu

Recently, both closed-source LLMs and open-source communities have made significant strides, outperforming humans in various general domains. However, their performance in specific professional fields such as medicine, especially within the…

Computation and Language · Computer Science 2024-06-19 Lulu Zhao , Weihao Zeng , Xiaofeng Shi , Hua Zhou , Donglin Hao , Yonghua Lin