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Spatial Frequency Domain Imaging can map tissue scattering and absorption properties over a wide field of view, making it useful for clinical applications such as wound assessment and surgical guidance. This technique has previously…

Biological Physics · Physics 2021-02-24 Mason T. Chen , Melina Papadakis , Nicholas J. Durr

Using optical speckle scanning microscopy [1], we demonstrate that clear images of multiple cells can be obtained through biological scattering tissue, with subcellular resolution and good image quality, as long as the size of the imaging…

Optics · Physics 2023-07-19 Xin Yang , Ye Pu , Demetri Psaltis

Synthetic aperture imaging has enabled breakthrough observations from radar to astronomy. However, optical implementation remains challenging due to stringent wavefield synchronization requirements among multiple receivers. Here we present…

Optical microscopy has so far been restricted to superficial layers, leaving many important biological questions unanswered. Random scattering causes the ballistic focus, which is conventionally used for image formation, to decay…

Optics · Physics 2012-08-28 Ke Si , Reto Fiolka , Meng Cui

Fibered confocal fluorescence microscopy (FCFM) is a new technique that can be used during a bronchoscopy to analyze the nature of the human bronchial and alveolar mucosa fluorescence microstructure. An endoscopic fibered confocal…

Medical Physics · Physics 2008-02-27 G. Bourg-Heckly , L. Thiberville , C. Vever-Bizet , B. Viellerobe

In astronomy, multi-object spectrographs employ fibre positioning robots to couple the light from multiple astronomy sources (stars or galaxies) into multiple multi-mode fibres, which are distributed across the focal plane of the telescope.…

Fluorescence microscopy is a powerful tool for imaging biological samples with molecular specificity. In contrast, phase microscopy provides label-free measurement of the sample's refractive index (RI), which is an intrinsic optical…

Optics · Physics 2022-01-26 Yi Xue , David Ren , Laura Waller

High-resolution optical microscopy suffers from a low contrast in scattering media where a multiply scattered wave obscures a ballistic wave used for image formation. To extend the imaging depth, various gating operations - confocal,…

Optics · Physics 2018-11-08 Mooseok Jang , Hakseok Ko , Won Kyu Lee , Jae-Seung Lee , Wonshik Choi

Spectral imaging enables the analysis of optical material properties that are invisible to the human eye. Different spectral capturing setups, e.g., based on filter-wheel, push-broom, line-scanning, or mosaic cameras, have been introduced…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Eric L. Wisotzky , Jost Triller , Anna Hilsmann , Peter Eisert

Endoscopy is essential in medical imaging, used for diagnosis, prognosis and treatment. Developing a robust dynamic 3D reconstruction pipeline for endoscopic videos could enhance visualization, improve diagnostic accuracy, aid in treatment…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Laura Salort-Benejam , Antonio Agudo

We report on the 3-dimensional imaging of biological cells including living neurons by a recently developed fibered interferometric Scanning Optical Microscope. The topography and surface structure of mouse fibroblasts and hippocampal…

Current in vivo microscopy allows us detailed spatiotemporal imaging (3D+t) of complete organisms and offers insights into their development on the cellular level. Even though the imaging speed and quality is steadily improving,…

Image and Video Processing · Electrical Eng. & Systems 2020-01-31 Sourabh Bhide , Ralf Mikut , Maria Leptin , Johannes Stegmaier

Integrated photonic circuits offer the possibility for complex quantum optical experiments in higher-dimensional photonic systems. However, the advantages of integration and scalability can only be fully utilized with the availability of a…

Ultrathin multimode fibers (MMFs) promise endoscopes with hair-scale diameters for accessing sub-millimeter anatomy, but in MMF far-field imaging the required small collection aperture drives speckle-dominated measurements that rapidly…

Optics · Physics 2026-01-21 Xianrui Zeng , Yirui Zang , Pengfei Liu , Fei Yu , Yang Yang , Tomáš Čižmár , Yang Du

High-resolution chemical imaging within deep tissues and intact spheroids remains a grand challenge. Here, we introduce mid-wave infrared photothermal (MWIP) microscopy operating in the underexplored 2000-2500 nm spectral window for…

Multi-mode fibers provide an increased amount of data transfer rates given a large number of transmission modes. Unfortunately, the increased number of modes in a multi-mode fiber hinders the accurate transfer of information due to…

Optics · Physics 2023-02-16 Alim Yolalmaz , Emre Yüce

Optical imaging through scattering media is an important challenge in a variety of fields ranging from microscopy to autonomous vehicles. While advanced wavefront shaping techniques have offered significant breakthroughs in the past decade,…

Optics · Physics 2023-05-23 Omri Haim , Jeremy Boger-Lombard , Ori Katz

On-invasive optical imaging techniques are essential diagnostic tools in many fields. Although various recent methods have been proposed to utilize and control light in multiple scattering media, non-invasive optical imaging through and…

Tapered optical fibers (TFs), with diameters gradually reduced from hundreds of microns to the micron scale, offer key advantages over conventional flat optical fibers (FFs), including uniform illumination, efficient long-range signal…

Optics · Physics 2026-02-03 Mingliang Xu , Fangyuan Li , Yuxin Leng , Ruxin Li , Fei He

We experimentally demonstrate an all-fiber spectrometer consisting of a photonic bandgap fiber bundle and a black and white CCD camera. Photonic crystal fibers used in this work are the large solid core all-plastic Bragg fibers designed for…

Optics · Physics 2015-05-18 Qu Hang , Bora Ung , Imran Syed , Ning Guo , Maksim Skorobogatiy