Related papers: Controllable Protein Sequence Generation with LLM …
Protein-specific large language models (Protein LLMs) are revolutionizing protein science by enabling more efficient protein structure prediction, function annotation, and design. While existing surveys focus on specific aspects or…
Deep learning has transformed protein design, enabling accurate structure prediction, sequence optimization, and de novo protein generation. Advances in single-chain protein structure prediction via AlphaFold2, RoseTTAFold, ESMFold, and…
Neural models that do not rely on pre-training have excelled in the keyphrase generation task with large annotated datasets. Meanwhile, new approaches have incorporated pre-trained language models (PLMs) for their data efficiency. However,…
The ability to automatically generate accurate protocols for scientific experiments would represent a major step towards the automation of science. Large Language Models (LLMs) have impressive capabilities on a wide range of tasks, such as…
Large language models (LLMs) have achieved remarkable success, yet aligning their generations with human preferences remains a critical challenge. Existing approaches to preference modeling often rely on an explicit or implicit reward…
Large Language Models (LLMs) have demonstrated great promise in generating code, especially when used inside an evolutionary computation framework to iteratively optimize the generated algorithms. However, in some cases they fail to…
Large language models (LLMs) have been recently leveraged as training data generators for various natural language processing (NLP) tasks. While previous research has explored different approaches to training models using generated data,…
Controlling output length in neural language generation is valuable in many scenarios, especially for the tasks that have length constraints. A model with stronger length control capacity can produce sentences with more specific length,…
Recently, there has been a surging interest in using large language models (LLMs) for Verilog code generation. However, the existing approaches are limited in terms of the quality of the generated Verilog code. To address such limitations,…
Generative modeling for protein engineering is key to solving fundamental problems in synthetic biology, medicine, and material science. We pose protein engineering as an unsupervised sequence generation problem in order to leverage the…
Current protein language models (PLMs) learn protein representations mainly based on their sequences, thereby well capturing co-evolutionary information, but they are unable to explicitly acquire protein functions, which is the end goal of…
Large language models (LLMs) providing generative AI have become popular to support software engineers in creating, summarizing, optimizing, and documenting source code. It is still unknown how LLMs can support control engineers using…
Recent advances in Protein Language Models (PLMs) have transformed protein engineering, yet unlike their counterparts in Natural Language Processing (NLP), current PLMs exhibit a fundamental limitation: they excel in either Protein Language…
The performance of pre-trained Large Language Models (LLMs) is often sensitive to nuances in prompt templates, requiring careful prompt engineering, adding costs in terms of computing and human effort. In this study, we present experiments…
Large Language Models (LLMs) still produce gender-stereotyped language even in occupation-neutral contexts that reflect deep societal biases (Rudinger et al., 2018). To address this, prior work has proposed prompting, constrained decoding…
Large language models (LLMs) effectively generate fluent text when the target output follows natural language patterns. However, structured prediction tasks confine the output format to a limited ontology, causing even very large models to…
While Large Language Models (LLMs) have demonstrated remarkable capabilities across diverse natural language processing tasks, aligning these models with varying human preferences across multiple objectives remains a significant challenge…
Protein language models (PLMs) face a fundamental divide: masked language models (MLMs) excel at fitness prediction while causal models enable generation, forcing practitioners to maintain separate architectures. We introduce…
Large transformer-based language models (LMs) trained on huge text corpora have shown unparalleled generation capabilities. However, controlling attributes of the generated language (e.g. switching topic or sentiment) is difficult without…
Advanced Planning and Scheduling (APS) systems have become indispensable for modern manufacturing operations, enabling optimized resource allocation and production efficiency in increasingly complex and dynamic environments. While…