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Multimodal foundation models have shown compelling but conflicting performance in medical image interpretation. However, the mechanisms by which these models integrate and prioritize different data modalities, including images and text,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Thomas Buckley , James A. Diao , Pranav Rajpurkar , Adam Rodman , Arjun K. Manrai

The generalization of the Transformer architecture via MetaFormer has reshaped our understanding of its success in computer vision. By replacing self-attention with simpler token mixers, MetaFormer provides strong baselines for vision…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Ron Keuth , Paul Kaftan , Mattias P. Heinrich

Modern Foundation Models (FMs) are typically trained on corpora spanning a wide range of different data modalities, topics and downstream tasks. Utilizing these models can be very computationally expensive and is out of reach for most…

Machine Learning · Computer Science 2025-06-09 Andrey Zhmoginov , Jihwan Lee , Mark Sandler

The development of medical vision-language foundation models has attracted significant attention in the field of medicine and healthcare due to their promising prospect in various clinical applications. While previous studies have commonly…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Weijian Huang , Cheng Li , Hong-Yu Zhou , Jiarun Liu , Hao Yang , Yong Liang , Guangming Shi , Hairong Zheng , Shanshan Wang

Image prior modeling is the key issue in image recovery, computational imaging, compresses sensing, and other inverse problems. Recent algorithms combining multiple effective priors such as the sparse or low-rank models, have demonstrated…

Image and Video Processing · Electrical Eng. & Systems 2020-03-31 Bihan Wen , Yanjun Li , Yuqi Li , Yoram Bresler

Current medical AI systems are often limited to narrow applications, hindering widespread adoption. We present MedVersa, a generalist foundation model trained on tens of millions of compiled medical instances. MedVersa unlocks generalist…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Hong-Yu Zhou , Julián Nicolás Acosta , Subathra Adithan , Suvrankar Datta , Eric J. Topol , Pranav Rajpurkar

Despite their successes in vision and language, foundation models have stumbled in pathology, revealing low accuracy, instability, and heavy computational demands. These shortcomings stem not from tuning problems but from deeper conceptual…

Artificial Intelligence · Computer Science 2026-04-21 Hamid R. Tizhoosh

Inevitable domain and task discrepancies in real-world scenarios can impair the generalization performance of the pre-trained deep models for medical data. Therefore, we audaciously propose that we should build a general-purpose medical AI…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Huahui Yi , Ziyuan Qin , Qicheng Lao , Wei Xu , Zekun Jiang , Dequan Wang , Shaoting Zhang , Kang Li

Image registration is fundamental in medical imaging applications, such as disease progression analysis or radiation therapy planning. The primary objective of image registration is to precisely capture the deformation between two or more…

Image and Video Processing · Electrical Eng. & Systems 2024-12-23 Anna Reithmeir , Veronika Spieker , Vasiliki Sideri-Lampretsa , Daniel Rueckert , Julia A. Schnabel , Veronika A. Zimmer

Few-shot learning has been studied to adapt models to tasks with very few samples. It holds profound significance, particularly in clinical tasks, due to the high annotation cost of medical images. Several works have explored few-shot…

Computer Vision and Pattern Recognition · Computer Science 2024-02-06 Kaipeng Zheng , Weiran Huang , Lichao Sun

Recent foundation models have demonstrated strong performance in medical image representation learning, yet their comparative behaviour across datasets remains underexplored. This work benchmarks two large-scale chest X-ray (CXR) embedding…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Jiho Shin , Dominic Marshall , Matthieu Komorowski

Despite the significant progress made by all-in-one models in universal image restoration, existing methods suffer from a generalization bottleneck in real-world scenarios, as they are mostly trained on small-scale synthetic datasets with…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Hao Li , Xiang Chen , Jiangxin Dong , Jinhui Tang , Jinshan Pan

Foundation models pretrained on diverse data at scale have demonstrated extraordinary capabilities in a wide range of vision and language tasks. When such models are deployed in real world environments, they inevitably interface with other…

Artificial Intelligence · Computer Science 2023-03-08 Sherry Yang , Ofir Nachum , Yilun Du , Jason Wei , Pieter Abbeel , Dale Schuurmans

Evaluating foundation models under appropriate adaptation settings is essential for understanding the quality and transferability of the learned representations. Recent EEG foundation models have demonstrated promising transfer capabilities…

Machine Learning · Computer Science 2026-05-28 Aditya Kommineni , Emily Zhou , Kleanthis Avramidis , Tiantian Feng , Shrikanth Narayanan

Transformers have dominated the field of natural language processing, and recently impacted the computer vision area. In the field of medical image analysis, Transformers have also been successfully applied to full-stack clinical…

Computer Vision and Pattern Recognition · Computer Science 2022-08-22 Kelei He , Chen Gan , Zhuoyuan Li , Islem Rekik , Zihao Yin , Wen Ji , Yang Gao , Qian Wang , Junfeng Zhang , Dinggang Shen

Breast cancer is the most common cancer type in women worldwide. Early detection and appropriate treatment can significantly reduce its impact. While histopathology examinations play a vital role in rapid and accurate diagnosis, they often…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Nematollah Saeidi , Hossein Karshenas , Bijan Shoushtarian , Sepideh Hatamikia , Ramona Woitek , Amirreza Mahbod

Accurate lung tumor segmentation is crucial for improving diagnosis, treatment planning, and patient outcomes in oncology. However, the complexity of tumor morphology, size, and location poses significant challenges for automated…

Image and Video Processing · Electrical Eng. & Systems 2026-02-16 Elena Mulero Ayllón , Massimiliano Mantegna , Linlin Shen , Paolo Soda , Valerio Guarrasi , Matteo Tortora

Medical images can be used to predict a clinical score coding for the severity of a disease, a pain level or the complexity of a cognitive task. In all these cases, the predicted variable has a natural order. While a standard classifier…

Machine Learning · Computer Science 2012-10-02 Fabian Pedregosa , Alexandre Gramfort , Gaël Varoquaux , Elodie Cauvet , Christophe Pallier , Bertrand Thirion

Foundation models have emerged as critical components in a variety of artificial intelligence applications, and showcase significant success in natural language processing and several other domains. Meanwhile, the field of graph machine…

Machine Learning · Computer Science 2025-03-11 Jiawei Liu , Cheng Yang , Zhiyuan Lu , Junze Chen , Yibo Li , Mengmei Zhang , Ting Bai , Yuan Fang , Lichao Sun , Philip S. Yu , Chuan Shi

With the advents of deep learning, improved image classification with complex discriminative models has been made possible. However, such deep models with increased complexity require a huge set of labeled samples to generalize the…

Machine Learning · Computer Science 2019-10-08 Walid Abdullah Al , Il Dong Yun