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To address the growing needs for scalable High Performance Computing (HPC) and Quantum Computing (QC) integration, we present our HPC-QC full stack framework and its hybrid workload development capability with modular…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-24 Xin Zhan , K. Grace Johnson , Aniello Esposito , Barbara Chapman , Marco Fiorentino , Kirk M. Bresniker , Raymond G. Beausoleil , Masoud Mohseni

Quantum machine learning (QML) holds the promise to solve classically intractable problems, but, as critical data can be fragmented across private clients, there is a need for distributed QML in a quantum federated learning (QFL) format.…

Quantum Physics · Physics 2025-10-09 Jason Han , Nicholas S. DiBrita , Daniel Leeds , Jianqiang Li , Jason Ludmir , Tirthak Patel

Quantum Machine Learning (QML) is considered one of the most promising applications of Quantum Computing in the Noisy Intermediate Scale Quantum (NISQ) era for the impact it is thought to have in the near future. Although promising…

Quantum Physics · Physics 2025-08-22 Valeria Repetto , Elia Giuseppe Ceroni , Giuseppe Buonaiuto , Romina D'Aurizio

At the intersection of quantum computing and machine learning, quantum machine learning (QML) is poised to revolutionize artificial intelligence. However, the vulnerability of the current generation of quantum computers to noise and…

Quantum Physics · Physics 2026-01-13 Eromanga Adermann , Haiyue Kang , Martin Sevior , Muhammad Usman

The availability of large-scale datasets on which to train, benchmark and test algorithms has been central to the rapid development of machine learning as a discipline and its maturity as a research discipline. Despite considerable…

Quantum Physics · Physics 2021-08-17 Elija Perrier , Akram Youssry , Chris Ferrie

Quantum machine learning (QML) is a discipline that seeks to transfer the advantages of quantum computing to data-driven tasks. However, many studies rely on toy datasets or heavy feature reduction, raising concerns about their scalability.…

Quantum Physics · Physics 2025-04-16 Federico Tiblias , Anna Schroeder , Yue Zhang , Mariami Gachechiladze , Iryna Gurevych

Although it will be a while before a practical quantum computer is available, there is no need to hold off. Methods and algorithms are being developed to demonstrate the feasibility of running machine learning (ML) pipelines in QC (Quantum…

Quantum Physics · Physics 2024-09-02 Prabhat Santi , Kamakhya Mishra , Sibabrata Mohanty

Machine learning and quantum computing are two technologies that are causing a paradigm shift in the performance and behavior of certain algorithms, achieving previously unattainable results. Machine learning (kernel classification) has…

Quantum Physics · Physics 2020-04-28 Siddharth Sharma

This tutorial intends to introduce readers with a background in AI to quantum machine learning (QML) -- a rapidly evolving field that seeks to leverage the power of quantum computers to reshape the landscape of machine learning. For…

We have developed two quantum classifier models for the $t\bar{t}H(b\bar{b})$ classification problem, both of which fall into the category of hybrid quantum-classical algorithms for Noisy Intermediate Scale Quantum devices (NISQ). Our…

Near-term quantum workloads are shaped by coupled compilation and execution choices: qubit layout, routing, basis translation, gate suppression, measurement mitigation, shot budget, and artifact reproducibility. This paper analyzes…

Quantum Physics · Physics 2026-05-06 Soumyadip Sarkar

Machine Learning (ML) serves as a general-purpose, highly adaptable, and versatile framework for investigating complex systems across domains. However, the resulting computational resource demands, in terms of the number of parameters and…

Instrumentation and Methods for Astrophysics · Physics 2025-07-29 Mansur Ziiatdinov , Farida Farsian , Francesco Schilliró , Salvatore Distefano

Despite significant efforts, the realization of the hybrid quantum-classical algorithms has predominantly been confined to proof-of-principles, mainly due to the hardware noise. With fault-tolerant implementation being a long-term goal,…

Quantum Physics · Physics 2025-04-10 Srushti Patil , Dibyendu Mondal , Rahul Maitra

Implementing Machine Learning (ML) models on Field-Programmable Gate Arrays (FPGAs) is becoming increasingly popular across various domains as a low-latency and low-power solution that helps manage large data rates generated by continuously…

Machine Learning · Computer Science 2024-08-13 Mohammad Mehdi Rahimifar , Hamza Ezzaoui Rahali , Audrey C. Therrien

Measuring a qubit state is a fundamental yet error-prone operation in quantum computing. These errors can arise from various sources, such as crosstalk, spontaneous state transitions, and excitations caused by the readout pulse. Here, we…

Implementation of variational Quantum Machine Learning (QML) algorithms on Noisy Intermediate-Scale Quantum (NISQ) devices is known to have issues related to the high number of qubits needed and the noise associated with multi-qubit gates.…

Quantum Physics · Physics 2020-07-21 Saurabh Kumar , Siddharth Dangwal , Debanjan Bhowmik

We present our development experience and recent results for the MLPerf Tiny Inference Benchmark on field-programmable gate array (FPGA) platforms. We use the open-source hls4ml and FINN workflows, which aim to democratize AI-hardware…

Integrating quantum mechanics into drug discovery marks a decisive shift from empirical trial-and-error toward quantitative precision. However, the prohibitive cost of ab initio molecular dynamics has historically forced a compromise…

We present a composable design scheme for the development of hybrid quantum/classical algorithms and workflows for applications of quantum simulation. Our object-oriented approach is based on constructing an expressive set of common data…