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Accurate disease interpretation from radiology remains challenging due to imaging heterogeneity. Achieving expert-level diagnostic decisions requires integration of subtle image features with clinical knowledge. Yet major vision-language…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Difei Gu , Yunhe Gao , Mu Zhou , Dimitris Metaxas

The emergence of Large Language Models (LLMs) presents unprecedented opportunities to revolutionize medical contrastive vision-language pre-training. In this paper, we show how LLMs can facilitate large-scale supervised pre-training,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yingtai Li , Haoran Lai , Xiaoqian Zhou , Shuai Ming , Wenxin Ma , Wei Wei , Shaohua Kevin Zhou

3D medical vision-language (VL) pretraining has shown potential in radiology by leveraging large-scale multimodal datasets with CT-report pairs. However, existing methods primarily rely on a global VL alignment directly adapted from 2D…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Jingyang Lin , Yingda Xia , Jianpeng Zhang , Ke Yan , Kai Cao , Le Lu , Jiebo Luo , Ling Zhang

Recent 3D CT vision-language models align volumes with reports via contrastive pretraining, but typically rely on limited public data and provide only coarse global supervision. We train a 3D CT vision-language model on 98k report-volume…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Simon Ging , Philipp Arnold , Sebastian Walter , Hani Alnahas , Hannah Bast , Elmar Kotter , Jiancheng Yang , Behzad Bozorgtabar , Thomas Brox

Foundation models trained via vision-language pretraining have demonstrated strong zero-shot capabilities across diverse image domains, yet their application to volumetric medical imaging remains limited. We introduce MedCT-VLM: Medical CT…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Thuraya Alzubaidi , Farhad R. Nezami , Muzammil Behzad

While Vision-Language Models (VLMs) have achieved notable progress in computational pathology (CPath), the gigapixel scale and spatial heterogeneity of Whole Slide Images (WSIs) continue to pose challenges for multimodal understanding.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Fengchun Liu , Songhan Jiang , Linghan Cai , Ziyue Wang , Yongbing Zhang

Fine-grained Vision-Language Pre-training (FVLP) demonstrates significant potential in 3D medical image understanding by aligning anatomy-level visual representations with corresponding textual descriptions. However, existing FVLP paradigms…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Hanwen Zhang , Yao Liu , Die Dai , Jiaye Yang , Qiao Liu , Yutong Xie , Peng Wang

Large annotated datasets are essential for training robust Computer-Aided Diagnosis (CAD) models for breast cancer detection or risk prediction. However, acquiring such datasets with fine-detailed annotation is both costly and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Shunjie-Fabian Zheng , Hyeonjun Lee , Thijs Kooi , Ali Diba

Medical vision-language pretraining (VLP) that leverages naturally-paired medical image-report data is crucial for medical image analysis. However, existing methods struggle to accurately characterize associations between images and…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Xinjie Liang , Xiangyu Li , Fanding Li , Jie Jiang , Qing Dong , Wei Wang , Kuanquan Wang , Suyu Dong , Gongning Luo , Shuo Li

The integration of artificial intelligence (AI) with radiology marks a transformative era in medicine. Vision foundation models have been adopted to enhance radiologic imaging analysis. However, the distinct complexities of radiologic 2D…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Zhixiu Lu , Hailong Li , Nehal A. Parikh , Jonathan R. Dillman , Lili He

Contrastive Language-Image Pre-training (CLIP) demonstrates strong potential in medical image analysis but requires substantial data and computational resources. Due to these restrictions, existing CLIP applications in medical imaging focus…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Yuexi Du , John Onofrey , Nicha C. Dvornek

Contrastive Language-Image Pre-training (CLIP) excels in multimodal tasks such as image-text retrieval and zero-shot classification but struggles with fine-grained understanding due to its focus on coarse-grained short captions. To address…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Chunyu Xie , Bin Wang , Fanjing Kong , Jincheng Li , Dawei Liang , Gengshen Zhang , Dawei Leng , Yuhui Yin

Accurate classification of focal liver lesions is crucial for diagnosis and treatment in hepatology. However, traditional supervised deep learning models depend on large-scale annotated datasets, which are often limited in medical imaging.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-07 Song Jian , Hu Yuchang , Wang Hui , Chen Yen-Wei

Obtaining large pre-trained models that can be fine-tuned to new tasks with limited annotated samples has remained an open challenge for medical imaging data. While pre-trained deep networks on ImageNet and vision-language foundation models…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Duy M. H. Nguyen , Hoang Nguyen , Nghiem T. Diep , Tan N. Pham , Tri Cao , Binh T. Nguyen , Paul Swoboda , Nhat Ho , Shadi Albarqouni , Pengtao Xie , Daniel Sonntag , Mathias Niepert

Radiologists highly desire fully automated versatile AI for medical imaging interpretation. However, the lack of extensively annotated large-scale multi-disease datasets has hindered the achievement of this goal. In this paper, we explore…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Weiwei Cao , Jianpeng Zhang , Yingda Xia , Tony C. W. Mok , Zi Li , Xianghua Ye , Le Lu , Jian Zheng , Yuxing Tang , Ling Zhang

Vision-Language Models (VLMs), such as CLIP, exhibit strong image-text comprehension abilities, facilitating advances in several downstream tasks such as zero-shot image classification, image-text retrieval, and text-to-image generation.…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Le Zhang , Rabiul Awal , Aishwarya Agrawal

Recent advancements in large-scale visual-language pre-trained models have led to significant progress in zero-/few-shot anomaly detection within natural image domains. However, the substantial domain divergence between natural and medical…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Chaoqin Huang , Aofan Jiang , Jinghao Feng , Ya Zhang , Xinchao Wang , Yanfeng Wang

Recent advances in AI combine large language models (LLMs) with vision encoders that bring forward unprecedented technical capabilities to leverage for a wide range of healthcare applications. Focusing on the domain of radiology,…

Fine-grained image classification, particularly in zero/few-shot scenarios, presents a significant challenge for vision-language models (VLMs), such as CLIP. These models often struggle with the nuanced task of distinguishing between…

Computation and Language · Computer Science 2024-05-21 Canshi Wei

The deployment of vision-language models (VLMs) in dermatology is hindered by the trilemma of high computational costs, extreme data scarcity, and the black-box nature of deep learning. To address these challenges, we present SkinCLIP-VL, a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Zhixiang Lu , Shijie Xu , Kaicheng Yan , Xuyue Cai , Chong Zhang , Yulong Li , Angelos Stefanidis , Anh Nguyen , Jionglong Su
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