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A numerical simulation infrastructure capable of calculating the flow of gas and the trajectories of particles through an aerodynamic lens injector is presented. The simulations increase the fundamental understanding and predict optimized…

Fluid Dynamics · Physics 2018-07-24 Nils Roth , Salah Awel , Daniel A. Horke , Jochen Küpper

The Direct Simulation Monte Carlo (DSMC) method was widely used to simulate low density gas flows with large Knudsen numbers. However, DSMC encounters limitations in the regime of lower Knudsen numbers (Kn<0.1). In such cases, approaches…

Purpose: Computational Fluid Dynamics (CFD) simulations are performed to investigate the impact of adding a grid to a two-inlet dry powder inhaler (DPI). The purpose of the paper is to show the importance of the correct choice of closure…

Computational Engineering, Finance, and Science · Computer Science 2021-01-27 David F Fletcher , Vishal Chaugule , Larissa Gomes dos Reis , Paul M Young , Daniela Traini , Julio Soria

An evolutionary multi-objective aerodynamic design optimization method using the computational fluid dynamics (CFD) simulations incorporating deep neural network (DNN) to reduce the required computational time is proposed. In this approach,…

Fluid Dynamics · Physics 2023-05-01 Yukito Tsunoda , Akira Oyama

The use of computational techniques in the design of dry powder inhalers (DPI), as well as in unravelling the complex mechanisms of drug aerosolization, has increased significantly in recent years. Computational fluid dynamics (CFD) is used…

Applied Physics · Physics 2025-09-15 Raffaele Ponzini , Roberto Da Vià , Simone Bnà , Ciro Cottini , Andrea Benassi

The design of microfluidic devices is a cumbersome and tedious process that can be significantly improved by simulation. Methods based on Computational Fluid Dynamics (CFD) are considered state-of-the-art, but require extensive compute time…

Computational Engineering, Finance, and Science · Computer Science 2024-01-17 Michel Takken , Robert Wille

The need for improved engine efficiencies has motivated the development of high-pressure combustion systems, in which operating conditions achieve and exceed critical conditions. Associated with these conditions are large thermodynamic…

Fluid Dynamics · Physics 2017-05-23 Peter C. Ma , Matthias Ihme , Luis Bravo

Computer simulation is an important tool for scientific progress, especially when lab experiments are either extremely costly and difficult or lack the required resolution. However, all of the simulation methods come with limitations. In…

Fluid Dynamics · Physics 2023-08-04 Edward R. Smith , Panagiotis E. Theodorakis

Computational fluid dynamics (CFD) studies have been increasingly used for blood flow simulations in intracranial aneurysms (ICAs). However, despite the continuous progress of body-fitted CFD solvers, generating a high quality mesh is still…

Computational Engineering, Finance, and Science · Computer Science 2020-07-28 D. S. Lampropoulos , G. C. Bourantas , B. F. Zwick , G. C. Kagadis , A. Wittek , K. Miller , V. C. Loukopoulos

The present study addresses the challenge of enhancing computational efficiency without compromising accuracy in numerical simulations of vacuum gas dynamics using the direct simulation Monte Carlo (DSMC) method. A technique termed "fixed…

Fluid Dynamics · Physics 2024-07-03 Moslem Sabouri , Ramin Zakeri , Amin Ebrahimi

Chemical vapor deposition (CVD) is a common industrial process that incorporates a complex combination of fluid flow, chemical reactions, and surface deposition. Understanding CVD processes requires rigorous and costly experimentation…

Fluid Dynamics · Physics 2025-09-09 Himel Barua , Alex Povitsky

Fluidic injection provides a promising solution to improve the performance of overexpanded single expansion ramp nozzle (SERN) during vehicle acceleration. However, determining the injection parameters for the best overall performance under…

Fluid Dynamics · Physics 2024-09-20 Yunjia Yang , Jiazhe Li , Yufei Zhang , Haixin Chen

Computational Fluid Dynamics (CFD) has become an indispensable tool in the optimization design, and evaluation of aircraft aerodynamics. However, solving the Navier-Stokes (NS) equations is a time-consuming, memory demanding and…

Fluid Dynamics · Physics 2023-12-08 Kuijun Zuo , Zhengyin Ye , Shuhui Bu , Xianxu Yuan , Weiwei Zhang

We present a hybrid continuum-atomistic scheme which combines molecular dynamics (MD) simulations with on-the-fly machine learning techniques for the accurate and efficient prediction of multiscale fluidic systems. By using a Gaussian…

Fluid Dynamics · Physics 2016-03-16 David Stephenson , James R Kermode , Duncan A Lockerby

Delivering sub-micrometer particles to an intense x-ray focus is a crucial aspect of single-particle diffractive-imaging experiments at x-ray free-electron lasers. Enabling direct visualization of sub-micrometer aerosol particle streams…

Single-particle x-ray diffractive imaging (SPI) of small (bio-)nanoparticles (NPs) requires optimized injectors to collect sufficient diffraction patterns to reconstruct the NP structure with high resolution. Typically,…

Instrumentation and Detectors · Physics 2021-06-01 Lena Worbs , Nils Roth , Jannik Lübke , Armando D. Estillore , P. Lourdu Xavier , Amit K. Samanta , Jochen Küpper

This study introduces a hybrid fluid simulation approach that integrates generative diffusion models with physics-based simulations, aiming at reducing the computational costs of flow simulations while still honoring all the physical…

A computational fluid dynamics (CFD) simulation framework for fluid-flow prediction is developed on the Tensor Processing Unit (TPU) platform. The TPU architecture is featured with accelerated dense matrix multiplication, large high…

Computational Physics · Physics 2022-03-02 Qing Wang , Matthias Ihme , Yi-Fan Chen , John Anderson

Computational Fluid Dynamics (CFD) simulations are often constrained by the memory-bound nature of sparse matrix-vector operations, which eventually limits performance on modern high-performance computing (HPC) systems. This work introduces…

Hydrogen fuel cells are a key technology in the transition toward carbon-neutral energy systems, offering clean power with water as the only byproduct. Microfluidic fuel cells, which operate at the microliter scale, are an emerging variant…

Computational Engineering, Finance, and Science · Computer Science 2026-03-31 Michel Takken , Robert Wille
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