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General-purpose large language models (LLMs) have demonstrated remarkable generative and reasoning capabilities but remain limited in healthcare and caregiving applications due to two key deficiencies: factual unreliability and a lack of…

Computation and Language · Computer Science 2025-12-09 Emre Umucu , Guillermina Solis , Leon Garza , Emilia Rivas , Beatrice Lee , Anantaa Kotal , Aritran Piplai

Large Language Models (LLMs) are increasingly applied in healthcare, yet ensuring their ethical integrity and safety compliance remains a major barrier to clinical deployment. This work introduces a multi-agent refinement framework designed…

Large language models (LLMs) have demonstrated remarkable capabilities in complex reasoning and text generation. However, these models can inadvertently generate unsafe or biased responses when prompted with problematic inputs, raising…

Computation and Language · Computer Science 2024-12-03 Avinash Amballa , Durga Sandeep Saluru , Gayathri Akkinapalli , Abhishek Sureddy , Akshay Kumar Sureddy

Large Language Models (LLMs) are increasingly used in healthcare, yet ensuring their safety and trustworthiness remains a barrier to deployment. Conversational medical assistants must avoid unsafe compliance without over-refusing benign…

Artificial Intelligence · Computer Science 2025-12-05 Huy Nghiem , Swetasudha Panda , Devashish Khatwani , Huy V. Nguyen , Krishnaram Kenthapadi , Hal Daumé

Large Language Models (LLMs) have become pivotal in advancing natural language processing, yet their potential to perpetuate biases poses significant concerns. This paper introduces a new framework employing Direct Preference Optimization…

Computation and Language · Computer Science 2024-07-22 Ahmed Allam

Large Language Models (LLMs) have demonstrated unprecedented generative capabilities, yet their alignment with human values remains critical for ensuring helpful and harmless deployments. While Reinforcement Learning from Human Feedback…

The widespread application of large language models (LLMs) raises increasing demands on ensuring safety or imposing constraints, such as reducing harmful content and adhering to predefined rules. While there have been several works studying…

Machine Learning · Computer Science 2026-02-13 Yihan Du , Seo Taek Kong , R. Srikant

Large Language Models (LLMs) have demonstrated remarkable performance across various domains, motivating researchers to investigate their potential use in recommendation systems. However, directly applying LLMs to recommendation tasks has…

Information Retrieval · Computer Science 2024-06-21 Zhuoxi Bai , Ning Wu , Fengyu Cai , Xinyi Zhu , Yun Xiong

Alignment of large language models (LLMs) has predominantly relied on pairwise preference optimization, where annotators select the better of two responses to a prompt. While simple, this approach overlooks the opportunity to learn from…

Machine Learning · Computer Science 2026-02-11 Yuxuan Tang , Yifan Feng

Recent advances in alignment techniques such as Supervised Fine-Tuning (SFT), Reinforcement Learning from Human Feedback (RLHF), and Direct Preference Optimization (DPO) have improved the safety of large language models (LLMs). However,…

Computation and Language · Computer Science 2026-02-26 Mengxuan Hu , Vivek V. Datla , Anoop Kumar , Zihan Guan , Sheng Li , Alfy Samuel , Daben Liu

The emergence of Large Language Models (LLMs) has fundamentally transformed natural language processing, making them indispensable across domains ranging from conversational systems to scientific exploration. However, their pre-trained…

Aligning the output of Large Language Models (LLMs) with human preferences (e.g., by means of reinforcement learning with human feedback, or RLHF) is essential for ensuring their effectiveness in real-world scenarios. Despite significant…

Artificial Intelligence · Computer Science 2024-10-23 Pietro Bernardelle , Gianluca Demartini

Aligning large language models (LLMs) with human values is an increasingly critical step in post-training. Direct Preference Optimization (DPO) has emerged as a simple, yet effective alternative to reinforcement learning from human feedback…

Artificial Intelligence · Computer Science 2025-07-29 Yifan Wang , Runjin Chen , Bolian Li , David Cho , Yihe Deng , Ruqi Zhang , Tianlong Chen , Zhangyang Wang , Ananth Grama , Junyuan Hong

Direct Preference Optimization (DPO) is an efficient alignment technique that steers LLMs towards preferable outputs by training on preference data, bypassing the need for explicit reward models. Its simplicity enables easy adaptation to…

With the introduction of ChatGPT, Large Language Models (LLMs) have received enormous attention in healthcare. Despite their potential benefits, researchers have underscored various ethical implications. While individual instances have…

Computers and Society · Computer Science 2024-07-09 Joschka Haltaufderheide , Robert Ranisch

Well-being encompasses mental, physical, and social dimensions essential to personal growth and informed life decisions. As individuals increasingly consult Large Language Models (LLMs) to understand well-being, a key challenge emerges: Can…

Computation and Language · Computer Science 2025-08-07 Bohan Jiang , Dawei Li , Zhen Tan , Chengshuai Zhao , Huan Liu

This work enhances the ability of large language models (LLMs) to perform complex reasoning in 3D scenes. Recent work has addressed the 3D situated reasoning task by invoking tool usage through large language models. Large language models…

Artificial Intelligence · Computer Science 2025-08-22 Jiayi Song , Rui Wan , Lipeng Ma , Weidong Yang , Qingyuan Zhou , Yixuan Li , Ben Fei

Existing training-time safety alignment techniques for large language models (LLMs) remain vulnerable to jailbreak attacks. Direct preference optimization (DPO), a widely deployed alignment method, exhibits limitations in both experimental…

Computation and Language · Computer Science 2025-10-31 Xuandong Zhao , Will Cai , Tianneng Shi , David Huang , Licong Lin , Song Mei , Dawn Song

Large Language Models (LLMs) have showcased their remarkable capabilities in diverse domains, encompassing natural language understanding, translation, and even code generation. The potential for LLMs to generate harmful content is a…

Software Engineering · Computer Science 2024-09-17 Mingke Yang , Yuqi Chen , Yi Liu , Ling Shi

Large Language Models (LLMs) exhibit impressive capabilities but also present risks such as biased content generation and privacy issues. One of the current alignment techniques includes principle-driven integration, but it faces challenges…

Computation and Language · Computer Science 2025-05-30 Yi Luo , Zhenghao Lin , Yuhao Zhang , Jiashuo Sun , Chen Lin , Chengjin Xu , Xiangdong Su , Yelong Shen , Jian Guo , Yeyun Gong
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