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Denoising Diffusion Probabilistic Model (DDPM) is able to make flexible conditional image generation from prior noise to real data, by introducing an independent noise-aware classifier to provide conditional gradient guidance at each time…

Computer Vision and Pattern Recognition · Computer Science 2022-09-21 Shengming Li , Guangcong Zheng , Hui Wang , Taiping Yao , Yang Chen , Shoudong Ding , Xi Li

Deep generative models are key-enabling technology to computer vision, text generation, and large language models. Denoising diffusion probabilistic models (DDPMs) have recently gained much attention due to their ability to generate diverse…

Quantum Physics · Physics 2026-02-02 Bingzhi Zhang , Peng Xu , Xiaohui Chen , Quntao Zhuang

Denoising Diffusion Probabilistic Models (DDPMs) have achieved remarkable success in various image generation tasks compared with Generative Adversarial Nets (GANs). Recent work on semantic image synthesis mainly follows the de facto…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Wengang Zhou , Weilun Wang , Jianmin Bao , Dongdong Chen , Dong Chen , Lu Yuan , Houqiang Li

Diffusion Probabilistic Models (DPMs) have recently shown remarkable performance in image generation tasks, which are capable of generating highly realistic images. When adopting DPMs for image restoration tasks, the crucial aspect lies in…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Yi Zhang , Xiaoyu Shi , Dasong Li , Xiaogang Wang , Jian Wang , Hongsheng Li

Denoising diffusion probabilistic models (DDPMs) are a recent family of generative models that achieve state-of-the-art results. In order to obtain class-conditional generation, it was suggested to guide the diffusion process by gradients…

Computer Vision and Pattern Recognition · Computer Science 2023-03-17 Bahjat Kawar , Roy Ganz , Michael Elad

Generating photos satisfying multiple constraints find broad utility in the content creation industry. A key hurdle to accomplishing this task is the need for paired data consisting of all modalities (i.e., constraints) and their…

Computer Vision and Pattern Recognition · Computer Science 2023-04-21 Nithin Gopalakrishnan Nair , Wele Gedara Chaminda Bandara , Vishal M. Patel

Based on the Denoising Diffusion Probabilistic Model (DDPM), medical image segmentation can be described as a conditional image generation task, which allows to compute pixel-wise uncertainty maps of the segmentation and allows an implicit…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Xutao Guo , Yanwu Yang , Chenfei Ye , Shang Lu , Yang Xiang , Ting Ma

Denoising Diffusion Probabilistic Models (DDPMs) can generate high-quality samples such as image and audio samples. However, DDPMs require hundreds to thousands of iterations to produce final samples. Several prior works have successfully…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Luping Liu , Yi Ren , Zhijie Lin , Zhou Zhao

We investigate whether synthetic images generated by diffusion models can enhance multi-label classification of protein subcellular localization. Specifically, we implement a simplified class-conditional denoising diffusion probabilistic…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Sylvey Lin , Zhi-Yi Cao

The vast applications of deep generative models are anchored in three core capabilities -- generating new instances, reconstructing inputs, and learning compact representations -- across various data types, such as discrete text/protein…

Machine Learning · Computer Science 2024-06-06 Guangyi Liu , Yu Wang , Zeyu Feng , Qiyu Wu , Liping Tang , Yuan Gao , Zhen Li , Shuguang Cui , Julian McAuley , Zichao Yang , Eric P. Xing , Zhiting Hu

Diffusion models have recently exhibited remarkable abilities to synthesize striking image samples since the introduction of denoising diffusion probabilistic models (DDPMs). Their key idea is to disrupt images into noise through a fixed…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Zijian Zhang , Zhou Zhao , Jun Yu , Qi Tian

Nowadays, denoising diffusion probabilistic models have been adapted for many image segmentation tasks. However, existing end-to-end models have already demonstrated remarkable capabilities. Rather than using denoising diffusion…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Shi Zhenning , Dong Changsheng , Xie Xueshuo , Pan Bin , He Along , Li Tao

Blind face restoration (BFR) is important while challenging. Prior works prefer to exploit GAN-based frameworks to tackle this task due to the balance of quality and efficiency. However, these methods suffer from poor stability and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Xinmin Qiu , Congying Han , Zicheng Zhang , Bonan Li , Tiande Guo , Xuecheng Nie

Denoising diffusion bridge models (DDBMs) are a powerful variant of diffusion models for interpolating between two arbitrary paired distributions given as endpoints. Despite their promising performance in tasks like image translation, DDBMs…

Machine Learning · Computer Science 2025-05-01 Kaiwen Zheng , Guande He , Jianfei Chen , Fan Bao , Jun Zhu

Denoising Diffusion Probabilistic Models (DDPMs) represent a contemporary class of generative models with exceptional qualities in both synthesis and maximizing the data likelihood. These models work by traversing a forward Markov Chain…

Machine Learning · Computer Science 2024-09-16 Hang Li , Wei Jin , Geri Skenderi , Harry Shomer , Wenzhuo Tang , Wenqi Fan , Jiliang Tang

With the advancement of diffusion models (DMs) and the substantially increased computational requirements, quantization emerges as a practical solution to obtain compact and efficient low-bit DMs. However, the highly discrete representation…

Computer Vision and Pattern Recognition · Computer Science 2025-02-03 Xingyu Zheng , Xianglong Liu , Haotong Qin , Xudong Ma , Mingyuan Zhang , Haojie Hao , Jiakai Wang , Zixiang Zhao , Jinyang Guo , Michele Magno

Denoising diffusion probabilistic models (DDPM) are a class of generative models which have recently been shown to produce excellent samples. We show that with a few simple modifications, DDPMs can also achieve competitive log-likelihoods…

Machine Learning · Computer Science 2021-02-22 Alex Nichol , Prafulla Dhariwal

Training deep learning methods on small time series datasets that also include corrupted samples is challenging. Diffusion models have shown to be effective to generate realistic and synthetic data, and correct corrupted samples through…

Machine Learning · Computer Science 2025-09-17 Julian Ripper , Ousama Esbel , Rafael Fietzek , Max Mühlhäuser , Thomas Kreutz

Despite the ever-increasing interest in applying deep learning (DL) models to medical imaging, the typical scarcity and imbalance of medical datasets can severely impact the performance of DL models. The generation of synthetic data that…

Image and Video Processing · Electrical Eng. & Systems 2023-04-03 Pouria Rouzrokh , Bardia Khosravi , Shahriar Faghani , Mana Moassefi , Sanaz Vahdati , Bradley J. Erickson

Light microscopy is a widespread and inexpensive imaging technique facilitating biomedical discovery and diagnostics. However, light diffraction barrier and imperfections in optics limit the level of detail of the acquired images. The…

Quantitative Methods · Quantitative Biology 2026-03-24 Rui Li , Gabriel della Maggiora , Vardan Andriasyan , Anthony Petkidis , Artsemi Yushkevich , Mikhail Kudryashev , Artur Yakimovich