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Chemotaxis plays a crucial role in a variety of processes in biology and ecology. In many instances, processes involving chemical attraction take place in fluids. One of the most studied PDE models of chemotaxis is given by Keller-Segel…

Analysis of PDEs · Mathematics 2016-06-29 Alexander Kiselev , Xiaoqian Xu

In this paper, we consider the fast numerical solution of an optimal control formulation of the Keller--Segel model for bacterial chemotaxis. Upon discretization, this problem requires the solution of huge-scale saddle point systems to…

Numerical Analysis · Mathematics 2018-06-25 Sergey Dolgov , John W. Pearson

In this paper, we address a distributed control problem for a system of partial differential equations describing the evolution of a tumor that takes the biological mechanism of chemotaxis into account. The system describing the evolution…

Optimization and Control · Mathematics 2023-09-19 Gianni Gilardi , Andrea Signori , Jürgen Sprekels

We describe and analyze a finite element numerical scheme for the parabolic-parabolic Keller-Segel model. The scalar auxiliary variable method is used to retrieve the monotonic decay of the energy associated with the system at the discrete…

Numerical Analysis · Mathematics 2020-07-06 Alexandre Poulain

The phenomenon where cells with elongated protrusions, such as neurons, communicate by contacting other cells and arrange themselves appropriately is termed cell sorting through haptotaxis. This phenomenon is described by partial…

Analysis of PDEs · Mathematics 2026-01-01 Hiroshi Ishii , Hideki Murakawa , Yoshitaro Tanaka

We study a regularized interacting particle method for computing aggregation patterns and near singular solutions of a Keller-Segal (KS) chemotaxis system in two and three space dimensions, then further develop DeepParticle (DP) method to…

Computational Physics · Physics 2024-01-30 Zhongjian Wang , Jack Xin , Zhiwen Zhang

In this paper, we improve the original Lagrange multiplier approach \cite{ChSh22,ChSh_II22} and introduce a new energy correction approach to construct a class of robust, positivity/bound-preserving, mass conserving and energy dissipative…

Numerical Analysis · Mathematics 2024-11-21 Zexiong Fang , Qing Cheng

We exploit the existence and nonlinear stability of boundary spike/layer solutions of the Keller-Segel system with logarithmic singular sensitivity in the half space, where the physical zero-flux and Dirichlet boundary conditions are…

Analysis of PDEs · Mathematics 2019-08-21 Jose A Carrillo , Jingyu Li , Zhian Wang

The purpose of this work is the study of \textit{chemotaxis} and how to model it through the equations of Keller-Segel. \textit{Chemotaxis} is a natural process which induces the organisms to direct their movement according to certain…

Analysis of PDEs · Mathematics 2021-11-24 Alejandro Fernández-Jiménez

A class of parabolic-parabolic Keller-Segel systems with degenerate diffusion and volume filling is studied in a bounded domain subject to no-flux boundary conditions. The equations are derived from a multiphase fluid model. The interplay…

Analysis of PDEs · Mathematics 2026-05-21 Noah Geltner , Ansgar Jüngel , Mingyue Zhang

We investigate the one-dimensional Keller-Segel model where the diffusion is replaced by a non-local operator, namely the fractional diffusion with exponent $0<\alpha\leq 2$. We prove some features related to the classical two-dimensional…

Analysis of PDEs · Mathematics 2015-05-13 Nikolaos Bournaveas , Vincent Calvez

A pathway-based mean-field theory (PBMFT) was recently proposed for E. coli chemotaxis in [G. Si, T. Wu, Q. Quyang and Y. Tu, Phys. Rev. Lett., 109 (2012), 048101]. In this paper, we derived a new moment system of PBMFT by using the moment…

Cell Behavior · Quantitative Biology 2013-04-29 Guangwei Si , Min Tang , Xu Yang

Perhaps the most classical diffusion model for chemotaxis is the Keller-Segel system \begin{equation}\tag{$\ast$} \label{ks0} \left\{ \begin{aligned} u_t =&\; \Delta u - \nabla \cdot(u \nabla v) \quad in {\mathbb R}^2\times(0,\infty),\\ v…

Analysis of PDEs · Mathematics 2023-02-16 Juan Davila , Manuel del Pino , Jean Dolbeault , Monica Musso , Juncheng Wei

Cells encounter a diverse array of physical and chemical signals as they navigate their natural surroundings. However, their response to the simultaneous presence of multiple cues remains elusive. Particularly, the impact of topography…

Analysis of PDEs · Mathematics 2026-03-10 Valeria Cuentas , Elio Espejo

We study a system of two coupled nonlinear parabolic equations. It constitutes a variant of the Keller-Segel model for chemotaxis, i.e. it models the behaviour of a population of bacteria that interact by means of a signalling substance. We…

Analysis of PDEs · Mathematics 2015-05-14 Jonathan Zinsl , Daniel Matthes

This manuscript deals with the three-dimensional version of a flux-limited Keller-Segel system coupled to the incompressible Stokes equations through transport and buoyancy. The main goal consists in verifying that within a certain…

Analysis of PDEs · Mathematics 2020-09-16 Michael Winkler

The Keller-Segel (KS) chemotaxis system is used to describe the overall behavior of a collection of cells under the influence of chemotaxis. However, solving the KS chemotaxis system and generating its aggregation patterns remain…

Numerical Analysis · Mathematics 2025-10-17 Yani Feng , Michael K. Ng , Zhiwen Zhang

In this paper, the well-posedness of two-dimensional signal-dependent Keller-Segel system and its mean-field derivation from a interacting particle system on the whole space are investigated. The signal dependence effect is reflected by the…

Analysis of PDEs · Mathematics 2025-06-05 Lukas Bol , Li Chen , Yue Li

In this paper, we are mainly concerned with the well-posed problem of the fractional Keller--Segel system in the framework of variable Lebesgue spaces. Based on carefully examining the algebraical structure of the system, we reduced the…

Analysis of PDEs · Mathematics 2024-05-03 Gastón Vergara-Hermosilla , Jihong Zhao

The Cellular Potts Model (CPM) has been used for simulating various biological phenomena such as differential adhesion, fruiting body formation of the slime mold Dictyostelium discoideum, angiogenesis, cancer invasion, chondrogenesis in…

Biological Physics · Physics 2009-11-11 Mark Alber , Nan Chen , Tilmann Glimm , Pavel M. Lushnikov
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