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Although digital breast tomosynthesis (DBT) improves diagnostic performance over full-field digital mammography (FFDM), false-positive recalls remain a concern in breast cancer screening. We developed a multi-modal artificial intelligence…

Image and Video Processing · Electrical Eng. & Systems 2025-04-14 Jungkyu Park , Jan Witowski , Yanqi Xu , Hari Trivedi , Judy Gichoya , Beatrice Brown-Mulry , Malte Westerhoff , Linda Moy , Laura Heacock , Alana Lewin , Krzysztof J. Geras

A major barrier to medical imaging research and in particular the development of artificial intelligence (AI) is a lack of large databases of medical images which share images with other researchers. Without such databases it is not…

A key promise of AI applications in healthcare is in increasing access to quality medical care in under-served populations and emerging markets. However, deep learning models are often only trained on data from advantaged populations that…

Image and Video Processing · Electrical Eng. & Systems 2019-11-04 Kevin Wu , Eric Wu , Yaping Wu , Hongna Tan , Greg Sorensen , Meiyun Wang , Bill Lotter

This research aims to investigate the classification accuracy of various state-of-the-art image classification models across different categories of breast ultrasound images, as defined by the Breast Imaging Reporting and Data System…

Image and Video Processing · Electrical Eng. & Systems 2023-11-16 Malitha Gunawardhana , Norbert Zolek

Purpose: Digital phantoms are one of the key components of virtual imaging trials (VITs) that aim to assess and optimize new medical imaging systems and algorithms. However, these phantoms vary in their voxel resolution, appearance, and…

Medical Physics · Physics 2024-02-02 Amar Kavuri , Mini Das

The past decade has witnessed a substantial increase in the number of startups and companies offering AI-based solutions for clinical decision support in medical institutions. However, the critical nature of medical decision-making raises…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Solha Kang , Wesley De Neve , Francois Rameau , Utku Ozbulak

The purpose of this study is the evaluation of the variation of performance in terms of sensitivity and specificity of two radiologists with different experience in mammography, with and without the assistance of two different CAD systems.…

Early detection of breast cancer is critical for improving patient outcomes. While mammography remains the primary screening modality, magnetic resonance imaging (MRI) is increasingly recommended as a supplemental tool for women with dense…

Breast cancer as a medical condition and mammograms as images exhibit many dimensions of variability across the population. Similarly, the way diagnostic systems are used and maintained by clinicians varies between imaging centres and…

Software Engineering · Computer Science 2007-05-23 S. Roberto Amendolia , Michael Brady , Richard McClatchey , Miguel Mulet-Parada , Mohammed Odeh , Tony Solomonides

Mammographic screening is an effective method for detecting breast cancer, facilitating early diagnosis. However, the current need to manually inspect images places a heavy burden on healthcare systems, spurring a desire for automated…

Image and Video Processing · Electrical Eng. & Systems 2025-01-30 Ciaran Bench , Emir Ahmed , Spencer A. Thomas

Breast cancer detection through mammography interpretation remains difficult because of the minimal nature of abnormalities that experts need to identify alongside the variable interpretations between readers. The potential of CNNs for…

Image and Video Processing · Electrical Eng. & Systems 2025-08-11 Ojonugwa Oluwafemi Ejiga Peter , Daniel Emakporuena , Bamidele Dayo Tunde , Maryam Abdulkarim , Abdullahi Bn Umar

Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer-related mortality in women globally. Mammography is essential for the early detection and diagnosis of breast lesions. Despite recent progress in foundation…

This work reveals undiscovered challenges in the performance and generalizability of deep learning models. We (1) identify spurious shortcuts and evaluation issues that can inflate performance and (2) propose training and analysis methods…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Trevor Tsue , Brent Mombourquette , Ahmed Taha , Thomas Paul Matthews , Yen Nhi Truong Vu , Jason Su

Mammography, or breast X-ray, is the most widely used imaging modality to detect cancer and other breast diseases. Recent studies have shown that deep learning-based computer-assisted detection and diagnosis (CADe or CADx) tools have been…

Image and Video Processing · Electrical Eng. & Systems 2023-03-20 Hieu T. Nguyen , Ha Q. Nguyen , Hieu H. Pham , Khanh Lam , Linh T. Le , Minh Dao , Van Vu

Over the past decades, computer-aided diagnosis tools for breast cancer have been developed to enhance screening procedures, yet their clinical adoption remains challenged by data variability and inherent biases. Although foundation models…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Elodie Germani , Ilayda Selin Türk , Fatima Zeineddine , Charbel Mourad , Shadi Albarqouni

Artificial intelligence (AI) is increasingly being utilized to optimize magnetic resonance imaging (MRI) protocols. Given that image details are critical for diagnostic accuracy, optimizing MRI acquisition protocols is essential for…

Machine Learning · Computer Science 2025-02-05 Alice Vian , Diego Andre Eifer , Mauricio Anes , Guilherme Ribeiro Garcia , Mariana Recamonde-Mendoza

To generate evidence regarding the safety and efficacy of artificial intelligence (AI) enabled medical devices, AI models need to be evaluated on a diverse population of patient cases, some of which may not be readily available. We propose…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 Elena Sizikova , Niloufar Saharkhiz , Diksha Sharma , Miguel Lago , Berkman Sahiner , Jana G. Delfino , Aldo Badano

An end-to-end image analysis pipeline is presented for the abdominal MRI protocol used in the UK Biobank on the first 38,971 participants. Emphasis is on the processing steps necessary to ensure a high-level of data quality and consistency…

Image and Video Processing · Electrical Eng. & Systems 2020-07-17 Nicolas Basty , Yi Liu , Madeleine Cule , E. Louise Thomas , Jimmy D. Bell , Brandon Whitcher

Several studies indicate that deep learning models can learn to detect breast cancer from mammograms (X-ray images of the breasts). However, challenges with overfitting and poor generalisability prevent their routine use in the clinic.…

Image and Video Processing · Electrical Eng. & Systems 2025-02-05 Emir Ahmed , Spencer A. Thomas , Ciaran Bench

Artificial intelligence (AI) has introduced numerous opportunities for human assistance and task automation in medicine. However, it suffers from poor generalization in the presence of shifts in the data distribution. In the context of…

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