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Deep learning has revolutionized image registration by its ability to handle diverse tasks while achieving significant speed advantages over conventional approaches. Current approaches, however, often employ globally uniform smoothness…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Xiang Chen , Fengting Zhang , Qinghao Liu , Min Liu , Kun Wu , Yaonan Wang , Hang Zhang

Medical image registration is a critical component of clinical imaging workflows, enabling accurate longitudinal assessment, multi-modal data fusion, and image-guided interventions. Intensity-based approaches often struggle with…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Eytan Kats , Mattias P. Heinrich

Clinical decision making from magnetic resonance imaging (MRI) combines complementary information from multiple MRI sequences (defined as 'modalities'). MRI image registration aims to geometrically 'pair' diagnoses from different…

Image and Video Processing · Electrical Eng. & Systems 2023-08-07 Chengjia Wang , Giorgos Papanastasiou

Modeling and manufacturing of personalized cranial implants are important research areas that may decrease the waiting time for patients suffering from cranial damage. The modeling of personalized implants may be partially automated by the…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Marek Wodzinski , Kamil Kwarciak , Mateusz Daniol , Daria Hemmerling

In medical imaging, most of the image registration methods implicitly assume a one-to-one correspondence between the source and target images (i.e., diffeomorphism). However, this is not necessarily the case when dealing with pathological…

Image and Video Processing · Electrical Eng. & Systems 2022-02-03 Matthis Maillard , Anton François , Joan Glaunès , Isabelle Bloch , Pietro Gori

In breast surgical planning, accurate registration of MR images across patient positions has the potential to improve the localisation of tumours during breast cancer treatment. While learning-based registration methods have recently become…

Affine registration is indispensable in a comprehensive medical image registration pipeline. However, only a few studies focus on fast and robust affine registration algorithms. Most of these studies utilize convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2022-03-31 Tony C. W. Mok , Albert C. S. Chung

Functional Magnetic Resonance Imaging (fMRI) is vital in neuroscience, enabling investigations into brain disorders, treatment monitoring, and brain function mapping. However, head motion during fMRI scans, occurring between shots of slice…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Samah Khawaled , Simon K. Warfield , Moti Freiman

We present a keypoint-based foundation model for general purpose brain MRI registration, based on the recently-proposed KeyMorph framework. Our model, called BrainMorph, serves as a tool that supports multi-modal, pairwise, and scalable…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Alan Q. Wang , Rachit Saluja , Heejong Kim , Xinzi He , Adrian Dalca , Mert R. Sabuncu

Magnetic Resonance Imaging (MRI) is a principal diagnostic approach used in the field of radiology to create images of the anatomical and physiological structure of patients. MRI is the prevalent medical imaging practice to find…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Yusuf Brima , Mossadek Hossain Kamal Tushar , Upama Kabir , Tariqul Islam

Deep learning approaches to the segmentation of magnetic resonance images have shown significant promise in automating the quantitative analysis of brain images. However, a continuing challenge has been its sensitivity to the variability of…

Image and Video Processing · Electrical Eng. & Systems 2021-03-05 Dzung L. Pham , Yi-Yu Chou , Blake E. Dewey , Daniel S. Reich , John A. Butman , Snehashis Roy

We present a fast learning-based algorithm for deformable, pairwise 3D medical image registration. Current registration methods optimize an objective function independently for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

The recent application of deep learning technologies in medical image registration has exponentially decreased the registration time and gradually increased registration accuracy when compared to their traditional counterparts. Most of the…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Abdullah Nazib , Clinton Fookes , Olivier Salvado , Dimitri Perrin

We propose LiftReg, a 2D/3D deformable registration approach. LiftReg is a deep registration framework which is trained using sets of digitally reconstructed radiographs (DRR) and computed tomography (CT) image pairs. By using simulated…

Image and Video Processing · Electrical Eng. & Systems 2023-04-05 Lin Tian , Yueh Z. Lee , Raúl San José Estépar , Marc Niethammer

Longitudinal analysis has great potential to reveal developmental trajectories and monitor disease progression in medical imaging. This process relies on consistent and robust joint 4D segmentation. Traditional techniques are dependent on…

Machine Learning · Computer Science 2019-06-19 Malav Bateriwala , Pierrick Bourgeat

Deep learning-based image registration approaches have shown competitive performance and run-time advantages compared to conventional image registration methods. However, existing learning-based approaches mostly require to train separate…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Yinsong Wang , Huaqi Qiu , Chen Qin

The loss function of an unsupervised multimodal image registration framework has two terms, i.e., a metric for similarity measure and regularization. In the deep learning era, researchers proposed many approaches to automatically learn the…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Zhe Xu , Jiangpeng Yan , Jie Luo , William Wells , Xiu Li , Jayender Jagadeesan

Image registration is a fundamental task that aligns anatomical structures between images. While CNNs perform well, they lack rotation equivariance - a rotated input does not produce a correspondingly rotated output. This hinders…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Arghavan Rezvani , Kun Han , Anthony T. Wu , Pooya Khosravi , Xiaohui Xie

Longitudinal MRIs are often used to capture the gradual deterioration of brain structure and function caused by aging or neurological diseases. Analyzing this data via machine learning generally requires a large number of ground-truth…

Computer Vision and Pattern Recognition · Computer Science 2021-06-21 Jiahong Ouyang , Qingyu Zhao , Ehsan Adeli , Edith V Sullivan , Adolf Pfefferbaum , Greg Zaharchuk , Kilian M Pohl

Purpose: To develop an efficient dual-domain reconstruction framework for multi-contrast MRI, with the focus on minimising cross-contrast misalignment in both the image and the frequency domains to enhance optimisation. Theory and Methods:…

Image and Video Processing · Electrical Eng. & Systems 2023-12-04 Junwei Yang , Pietro Liò