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Predicting future brain state from a baseline magnetic resonance image (MRI) is a central challenge in neuroimaging and has important implications for studying neurodegenerative diseases such as Alzheimer's disease (AD). Most existing…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Ali Farki , Elaheh Moradi , Deepika Koundal , Jussi Tohka

Medical image registration is critical for aligning anatomical structures across imaging modalities such as computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound. Among existing techniques, non-rigid registration (NRR)…

Image and Video Processing · Electrical Eng. & Systems 2025-12-17 Sneha Sree C. , Dattesh Shanbhag , Sudhanya Chatterjee

Conventional deformable registration methods aim at solving an optimization model carefully designed on image pairs and their computational costs are exceptionally high. In contrast, recent deep learning based approaches can provide fast…

Computer Vision and Pattern Recognition · Computer Science 2021-10-01 Risheng Liu , Zi Li , Xin Fan , Chenying Zhao , Hao Huang , Zhongxuan Luo

In human neuroimaging studies, atlas registration enables mapping MRI scans to a common coordinate frame, which is necessary to aggregate data from multiple subjects. Machine learning registration methods have achieved excellent speed and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Karthik Gopinath , Xiaoling Hu , Malte Hoffmann , Oula Puonti , Juan Eugenio Iglesias

Non-rigid registration is a necessary but challenging task in medical imaging studies. Recently, unsupervised registration models have shown good performance, but they often require a large-scale training dataset and long training times.…

Computer Vision and Pattern Recognition · Computer Science 2021-04-22 Heejung Park , Gyeong Min Lee , Soopil Kim , Ga Hyung Ryu , Areum Jeong , Sang Hyun Park , Min Sagong

We propose a novel non-rigid image registration algorithm that is built upon fully convolutional networks (FCNs) to optimize and learn spatial transformations between pairs of images to be registered. Different from most existing deep…

Computer Vision and Pattern Recognition · Computer Science 2017-09-05 Hongming Li , Yong Fan

Magnetic Resonance Imaging (MRI) typically recruits multiple sequences (defined here as "modalities"). As each modality is designed to offer different anatomical and functional clinical information, there are evident disparities in the…

Image and Video Processing · Electrical Eng. & Systems 2022-03-09 Chengjia Wang , Guang Yang , Giorgos Papanastasiou

Multi-contrast magnetic resonance (MR) image registration is useful in the clinic to achieve fast and accurate imaging-based disease diagnosis and treatment planning. Nevertheless, the efficiency and performance of the existing registration…

Image and Video Processing · Electrical Eng. & Systems 2021-02-17 Weijian Huang , Hao Yang , Xinfeng Liu , Cheng Li , Ian Zhang , Rongpin Wang , Hairong Zheng , Shanshan Wang

We present KeyMorph, a deep learning-based image registration framework that relies on automatically detecting corresponding keypoints. State-of-the-art deep learning methods for registration often are not robust to large misalignments, are…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Alan Q. Wang , Evan M. Yu , Adrian V. Dalca , Mert R. Sabuncu

This dissertation is devoted to provide advanced nonconvex nonsmooth variational models of (Magnetic Resonance Image) MRI reconstruction, efficient learnable image reconstruction algorithms and parameter training algorithms that improve the…

Optimization and Control · Mathematics 2023-03-06 Wanyu Bian

Image registration with deep neural networks has become an active field of research and exciting avenue for a long standing problem in medical imaging. The goal is to learn a complex function that maps the appearance of input image pairs to…

Computer Vision and Pattern Recognition · Computer Science 2019-07-23 Matthew C. H. Lee , Ozan Oktay , Andreas Schuh , Michiel Schaap , Ben Glocker

Purpose: This study aims to explore training strategies to improve convolutional neural network-based image-to-image deformable registration for abdominal imaging. Methods: Different training strategies, loss functions, and transfer…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Javier Pérez de Frutos , André Pedersen , Egidijus Pelanis , David Bouget , Shanmugapriya Survarachakan , Thomas Langø , Ole-Jakob Elle , Frank Lindseth

Deformable medical image registration is an essential task in computer-assisted interventions. This problem is particularly relevant to oncological treatments, where precise image alignment is necessary for tracking tumor growth, assessing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Stefano Fogarollo , Gregor Laimer , Reto Bale , Matthias Harders

Medical image registration is a challenging task involving the estimation of spatial transformations to establish anatomical correspondence between pairs or groups of images. Recently, deep learning-based image registration methods have…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Xiang Chen , Yan Xia , Nishant Ravikumar , Alejandro F Frangi

Recent works in medical image registration have proposed the use of Implicit Neural Representations, demonstrating performance that rivals state-of-the-art learning-based methods. However, these implicit representations need to be optimized…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Louis D. van Harten , Jaap Stoker , Ivana Išgum

Registration is a fundamental task in medical robotics and is often a crucial step for many downstream tasks such as motion analysis, intra-operative tracking and image segmentation. Popular registration methods such as ANTs and NiftyReg…

Computer Vision and Pattern Recognition · Computer Science 2021-03-26 Wentao Zhu , Yufang Huang , Daguang Xu , Zhen Qian , Wei Fan , Xiaohui Xie

Objective: Deformable brain MR image registration is challenging due to large inter-subject anatomical variation. For example, the highly complex cortical folding pattern makes it hard to accurately align corresponding cortical structures…

Computer Vision and Pattern Recognition · Computer Science 2019-02-07 Dongming Wei , Zhengwang Wu , Gang Li , Xiaohuan Cao , Dinggang Shen , Qian Wang

Image registration is used in many medical image analysis applications, such as tracking the motion of tissue in cardiac images, where cardiac kinematics can be an indicator of tissue health. Registration is a challenging problem for deep…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Benjamin Graham

Nonrigid registration is vital to medical image analysis but remains challenging for diffusion MRI (dMRI) due to its high-dimensional, orientation-dependent nature. While classical methods are accurate, they are computationally demanding,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-13 Gianfranco Cortes , Xiaoda Qu , Baba C. Vemuri

Objective: Deep learning-based deformable image registration has achieved strong accuracy, but remains sensitive to variations in input image characteristics such as artifacts, field-of-view mismatch, or modality difference. We aim to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Yihao Liu , Junyu Chen , Lianrui Zuo , Shuwen Wei , Brian D. Boyd , Carmen Andreescu , Olusola Ajilore , Warren D. Taylor , Aaron Carass , Bennett A. Landman