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Gait analysis of patients with neurological disorders, including multiple sclerosis (MS), is important for rehabilitation and treatment. The Mircrosoft Kinect sensor, which was developed for motion recognition in gaming applications, is an…

Computer Vision and Pattern Recognition · Computer Science 2015-08-12 Farnood Gholami , Daria A. Trojan , Jozsef Kovecses , Wassim M. Haddad , Behnood Gholami

Longitudinal passive sensing studies for health and behavior outcomes often have missing and incomplete data. Handling missing data effectively is thus a critical data processing and modeling step. Our formative interviews with researchers…

Environmental, Social, and Governance (ESG) datasets are frequently plagued by significant data gaps, leading to inconsistencies in ESG ratings due to varying imputation methods. This paper explores the application of established machine…

Machine Learning · Computer Science 2024-07-30 Sergio Caprioli , Jacopo Foschi , Riccardo Crupi , Alessandro Sabatino

Background Multiple sclerosis (MS) is a complex immune-mediated disease with no currently known cure. There is growing evidence to support the role of diet in reducing some of the symptoms and disease progression in MS, and we previously…

Other Quantitative Biology · Quantitative Biology 2024-04-23 RD Russell , J He , LJ Black , A Begley

Alzheimers Disease AD is an acute neuro disease that degenerates the brain cells and thus leads to memory loss progressively. It is a fatal brain disease that mostly affects the elderly. It steers the decline of cognitive and biological…

Machine Learning · Computer Science 2023-04-20 Nair Bini Balakrishnan , P. S. Sreeja , Jisha Jose Panackal

Dementia is a complex syndrome impacting cognitive and emotional functions, with Alzheimer's disease being the most common form. This study focuses on enhancing dementia prediction using machine learning (ML) techniques on patient health…

Artificial Intelligence · Computer Science 2026-01-13 Shafiul Ajam Opee , Nafiz Fahad , Anik Sen , Rasel Ahmed , Fariha Jahan , Md. Kishor Morol , Md Rashedul Islam

Musculoskeletal and neurological disorders are the most common causes of walking problems among older people, and they often lead to diminished quality of life. Analyzing walking motion data manually requires trained professionals and the…

Computer Vision and Pattern Recognition · Computer Science 2022-08-19 Manli Zhu , Qianhui Men , Edmond S. L. Ho , Howard Leung , Hubert P. H. Shum

Structural magnetic resonance imaging (MRI) can be used to detect lesions in the brains of multiple sclerosis (MS) patients. The formation of these lesions is a complex process involving inflammation, tissue damage, and tissue repair, all…

Accurate imputation is essential for the reliability and success of downstream tasks. Recently, diffusion models have attracted great attention in this field. However, these models neglect the latent distribution in a lower-dimensional…

Machine Learning · Computer Science 2024-09-16 Guojun Liang , Najmeh Abiri , Atiye Sadat Hashemi , Jens Lundström , Stefan Byttner , Prayag Tiwari

Diabetes impacts the quality of life of millions of people. However, diabetes diagnosis is still an arduous process, given that the disease develops and gets treated outside the clinic. The emergence of wearable medical sensors (WMSs) and…

Computer Vision and Pattern Recognition · Computer Science 2019-10-14 Hongxu Yin , Bilal Mukadam , Xiaoliang Dai , Niraj K. Jha

Objective: Until now, traditional invasive approaches have been the only means being leveraged to diagnose spinal disorders. Traditional manual diagnostics require a high workload, and diagnostic errors are likely to occur due to the…

Artificial Intelligence · Computer Science 2023-02-08 Seyed Mohammad Sadegh Dashti , Seyedeh Fatemeh Dashti

Data on functional disability are of widespread policy interest in the United States, especially with respect to planning for Medicare and Social Security for a growing population of elderly adults. We consider an extract of functional…

Applications · Statistics 2009-09-29 Elena A. Erosheva , Stephen E. Fienberg , Cyrille Joutard

Unique identification of multiple sclerosis (MS) white matter lesions (WMLs) is important to help characterize MS progression. WMLs are routinely identified from magnetic resonance images (MRIs) but the resultant total lesion load does not…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Carlos A. Rivas , Jinwei Zhang , Shuwen Wei , Samuel W. Remedios , Aaron Carass , Jerry L. Prince

Alzheimer's disease (AD) is a prevalent neurodegenerative disorder that progressively impairs memory, decision-making, and overall cognitive function. As AD is irreversible, early prediction is critical for timely intervention and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Mahdieh Behjat Khatooni , Mohsen Soryani

Blinded sample size re-estimation and information monitoring based on blinded data has been suggested to mitigate risks due to planning uncertainties regarding nuisance parameters. Motivated by a randomized controlled trial in pediatric…

Applications · Statistics 2019-03-07 Tobias Mütze , Susanna Salem , Norbert Benda , Heinz Schmidli , Tim Friede

Amyotrophic lateral sclerosis is a fatal disease that not only affects movement, speech, and breath but also cognition. Recent studies have focused on the use of language analysis techniques to detect ALS and infer scales for monitoring…

Computation and Language · Computer Science 2023-09-14 Carla Agurto , Guillermo Cecchi , Bo Wen , Ernest Fraenkel , James Berry , Indu Navar , Raquel Norel

We develop a novel doubly-robust (DR) imputation framework for longitudinal studies with monotone dropout, motivated by the informative dropout that is common in FDA-regulated trials for Alzheimer's disease. In this approach, the missing…

Methodology · Statistics 2023-05-05 Yuqi Qiu , Karen Messer

People with mobility impairments are often recommended for gait assessment studies to diagnose their condition and to select appropriate physiotherapy to improve their mobility. These studies are often conducted in clinical or lab settings,…

Signal Processing · Electrical Eng. & Systems 2023-02-09 Rafael Castro Aguiar , Edward Jero , Samit Chakrabarty

Accurate forecasts of macroeconomic and financial data, such as GDP, CPI, unemployment rates, and stock indices, are crucial for the success of countries, businesses, and investors, resulting in a constant demand for reliable forecasting…

Methodology · Statistics 2025-10-27 Tomasz M. Łapiński , Krzysztof Ziółkowski

Parkinson's disease (PD) is a chronic neurodegenerative disease. It shows multiple motor symptoms such as tremor, bradykinesia, postural instability, freezing of gait (FoG). PD is currently diagnosed clinically through physical exam by…

Machine Learning · Computer Science 2026-04-21 Meheru Zannat