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When surveillance data of infectious disease incidence (e.g. weekly case counts) are disaggregated by demographic indicators, disparities in long-run health outcomes between these groups become apparent. Accurate identification of high-risk…

Methodology · Statistics 2026-05-29 Miles Moran , Rob Trangucci , Lisa Madsen

The COVID-19 pandemic provides new motivation for a classic problem in epidemiology: estimating the empirical rate of transmission during an outbreak (formally, the time-varying reproduction number) from case counts. While standard methods…

Methodology · Statistics 2020-12-08 Bryan Wilder , Michael J. Mina , Milind Tambe

Current epidemics in the biological and social domains are challenging the standard assumptions of mathematical contagion models. Chief among them are the complex patterns of transmission caused by heterogeneous group sizes and infection…

Physics and Society · Physics 2024-01-03 Guillaume St-Onge , Laurent Hébert-Dufresne , Antoine Allard

Understanding the process by which a contagion disseminates throughout a network is of great importance in many real world applications. The required sophistication of the inference approach depends on the type of information we want to…

Social and Information Networks · Computer Science 2017-05-26 Shohreh Shaghaghian , Mark Coates

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

Social and Information Networks · Computer Science 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

When modelling HIV epidemics, it is important to incorporate set-point viral load and its heritability. As set-point viral load distributions can differ significantly amongst epidemics, it is imperative to account for the observed local…

Populations and Evolution · Quantitative Biology 2018-11-28 Pieter Libin , Laurens Hernalsteen , Kristof Theys , Perpetua Gomes , Ana Abecasis , Ann Nowe

Epidemics are inherently stochastic, and stochastic models provide an appropriate way to describe and analyse such phenomena. Given temporal incidence data consisting of, for example, the number of new infections or removals in a given time…

Methodology · Statistics 2024-05-24 Sam A. Whitaker , Andrew Golightly , Colin S. Gillespie , Theodore Kypraios

In the present paper, our goal is to establish a framework for the mathematical modelling and the analysis of the spread of an epidemic in a large population commuting regularly, typically along a time-periodic pattern, as is roughly…

Populations and Evolution · Quantitative Biology 2024-08-29 Pierre-Alexandre Bliman , Boureima Sangaré , Assane Savadogo

Infectious disease superspreading caused by heterogeneity in contact behavior has been observed to be an important determinant of epidemic dynamics and size in both empirical and theoretical settings. However, it has also been observed that…

Populations and Evolution · Quantitative Biology 2026-01-27 Ari S. Freedman , Bjarke F. Nielsen , Maximillian M. Nguyen , Laurent Hébert-Dufresne , Simon A. Levin

We present a modelling framework for the spreading of epidemics on temporal networks from which both the individual-based and pair-based models can be recovered. The proposed temporal pair-based model that is systematically derived from…

Physics and Society · Physics 2020-11-17 Rory Humphries , Kieran Mulchrone , Jamie Tratalos , Simon More , Philipp Hövel

We describe a new method for evaluating Bayes factors. The key idea is to introduce a hypermodel in which the competing models are components of a mixture distribution. Inference for the mixing probabilities then yields estimates of the…

Methodology · Statistics 2016-02-16 Philip D. O'Neill , Theodore Kypraios

In this paper we investigate a susceptible-infected-susceptible (SIS) epidemic model describing data dissemination in opportunistic networks with heterogeneous setting of transmission parameters. We obtained the estimation of the final…

Social and Information Networks · Computer Science 2014-03-28 Vadim Alexeev , Liudmila Rozanova , Alexander Temerev

This article analyzes the problem of estimating the time until an event occurs, also known as survival modeling. We observe through substantial experiments on large real-world datasets and use-cases that populations are largely…

Machine Learning · Computer Science 2019-05-13 David Hubbard , Benoit Rostykus , Yves Raimond , Tony Jebara

Social contact matrices are essential tools in infectious disease epidemiology as they quantify close-range human contact patterns which directly drive the transmission of airborne infectious diseases. In this work we propose a Bayesian…

Methodology · Statistics 2026-05-11 Shozen Dan , David A. van Dyk , Zhi Ling , Swapnil Mishra , Oliver Ratmann

Infectious disease spread is a multi-scale process composed of within-host (biological) and between-host (social) drivers and disentangling them from each other is a central challenge in epidemiology. Here, we introduce VIBES, a multi-scale…

Traditional disease transmission models assume that the infectious period is exponentially distributed with a recovery rate fixed in time and across individuals. This assumption provides analytical and computational advantages, however it…

Populations and Evolution · Quantitative Biology 2024-01-30 Laura Di Domenico , Eugenio Valdano , Vittoria Colizza

The analysis of data from multiple experiments, such as observations of several individuals, is commonly approached using mixed-effects models, which account for variation between individuals through hierarchical representations. This makes…

Computation · Statistics 2026-03-05 Henrik Häggström , Sebastian Persson , Marija Cvijovic , Umberto Picchini

The purpose of this study is to leverage modern technology (such as mobile or web apps in Beckman et al. (2014)) to enrich epidemiology data and infer the transmission of disease. Homogeneity related research on population level has been…

Applications · Statistics 2015-09-02 Kai Fan , Allison E. Aiello , Katherine A. Heller

It is well recognised that animal and plant pathogens form complex ecological communities of interacting organisms within their hosts. Although community ecology approaches have been applied to determine pathogen interactions at the…

Epidemic models often reflect characteristic features of infectious spreading processes by coupled non-linear differential equations considering different states of health (such as Susceptible, Infected, or Recovered). This compartmental…

Physics and Society · Physics 2021-12-01 Vaiva Vasiliauskaite , Nino Antulov-Fantulin , Dirk Helbing