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Cytology slides are essential tools in diagnosing and staging cancer, but their analysis is time-consuming and costly. Foundation models have shown great potential to assist in these tasks. In this paper, we explore how existing foundation…

Image and Video Processing · Electrical Eng. & Systems 2024-11-25 Manon Dausort , Tiffanie Godelaine , Maxime Zanella , Karim El Khoury , Isabelle Salmon , Benoît Macq

Accurate and robust cell nuclei classification is the cornerstone for a wider range of tasks in digital and Computational Pathology. However, most machine learning systems require extensive labeling from expert pathologists for each…

Quantitative Methods · Quantitative Biology 2016-12-05 Stefan Bauer , Nicolas Carion , Peter Schüffler , Thomas Fuchs , Peter Wild , Joachim M. Buhmann

Accurate prostate cancer diagnosis remains challenging. Even when using MRI, radiologists exhibit low specificity and significant inter-observer variability, leading to potential delays or inaccuracies in identifying clinically significant…

Artificial intelligence foundation models are increasingly deployed for prostate cancer Gleason grading, where GP3/GP4 distinction directly impacts treatment decisions. However, these models may achieve high validation accuracy by learning…

Computer Vision and Pattern Recognition · Computer Science 2025-12-18 Joshua L. Ebbert , Dennis Della Corte

Continual learning (CL) methods designed for natural image classification often fail to reach basic quality standards for medical image segmentation. Atlas-based segmentation, a well-established approach in medical imaging, incorporates…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Amin Ranem , Camila González , Daniel Pinto dos Santos , Andreas M. Bucher , Ahmed E. Othman , Anirban Mukhopadhyay

Supervised training of deep learning models requires large labeled datasets. There is a growing interest in obtaining such datasets for medical image analysis applications. However, the impact of label noise has not received sufficient…

Computer Vision and Pattern Recognition · Computer Science 2020-03-24 Davood Karimi , Haoran Dou , Simon K. Warfield , Ali Gholipour

We hypothesize that anatomical priors can be viable mediums to infuse domain-specific clinical knowledge into state-of-the-art convolutional neural networks (CNN) based on the U-Net architecture. We introduce a probabilistic population…

Image and Video Processing · Electrical Eng. & Systems 2021-09-22 Anindo Saha , Matin Hosseinzadeh , Henkjan Huisman

We present a multi-stage 3D computer-aided detection and diagnosis (CAD) model for automated localization of clinically significant prostate cancer (csPCa) in bi-parametric MR imaging (bpMRI). Deep attention mechanisms drive its detection…

Image and Video Processing · Electrical Eng. & Systems 2021-07-02 Anindo Saha , Matin Hosseinzadeh , Henkjan Huisman

Deep learning based medical image diagnosis has shown great potential in clinical medicine. However, it often suffers two major difficulties in practice: 1) only limited labeled samples are available due to expensive annotation costs over…

Machine Learning · Computer Science 2019-11-19 Yifan Zhang , Ying Wei , Peilin Zhao , Shuaicheng Niu , Qingyao Wu , Mingkui Tan , Junzhou Huang

Early detection, accurate segmentation, classification and tracking of polyps during colonoscopy are critical for preventing colorectal cancer. Many existing deep-learning-based methods for analyzing colonoscopic videos either require…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Anwesa Choudhuri , Zhongpai Gao , Meng Zheng , Benjamin Planche , Terrence Chen , Ziyan Wu

This study focuses on comparing deep learning methods for the segmentation and quantification of uncertainty in prostate segmentation from MRI images. The aim is to improve the workflow of prostate cancer detection and diagnosis. Seven…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Pablo Cesar Quihui-Rubio , Daniel Flores-Araiza , Gilberto Ochoa-Ruiz , Miguel Gonzalez-Mendoza , Christian Mata

Survival analysis has been developed and applied in the number of areas including manufacturing, finance, economics and healthcare. In healthcare domain, usually clinical data are high-dimensional, sparse and complex and sometimes there…

Machine Learning · Computer Science 2018-08-13 Milad Zafar Nezhad , Najibesadat Sadati , Kai Yang , Dongxiao Zhu

Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Andrey Ignatov , Josephine Yates , Valentina Boeva

Recent advancements in deep learning have proven highly effective in medical image classification, notably within histopathology. However, noisy labels represent a critical challenge in histopathology image classification, where accurate…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Lucas Dedieu , Nicolas Nerrienet , Adrien Nivaggioli , Clara Simmat , Marceau Clavel , Arnaud Gauthier , Stéphane Sockeel , Rémy Peyret

Nuclei segmentation is a fundamental task in digital pathology analysis and can be automated by deep learning-based methods. However, the development of such an automated method requires a large amount of data with precisely annotated masks…

Computer Vision and Pattern Recognition · Computer Science 2021-11-25 Jiangbo Shi , Chang Jia , Zeyu Gao , Tieliang Gong , Chunbao Wang , Chen Li

Data augmentation refers to a group of techniques whose goal is to battle limited amount of available data to improve model generalization and push sample distribution toward the true distribution. While different augmentation strategies…

Quantitative Methods · Quantitative Biology 2020-06-03 Ruqian Hao , Khashayar Namdar , Lin Liu , Masoom A. Haider , Farzad Khalvati

With the wealth of medical image data, efficient curation is essential. Assigning the sequence type to magnetic resonance images is necessary for scientific studies and artificial intelligence-based analysis. However, incomplete or missing…

Image and Video Processing · Electrical Eng. & Systems 2024-08-01 Deepa Krishnaswamy , Bálint Kovács , Stefan Denner , Steve Pieper , David Clunie , Christopher P. Bridge , Tina Kapur , Klaus H. Maier-Hein , Andrey Fedorov

Deep neural networks have introduced significant advancements in the field of machine learning-based analysis of digital pathology images including prostate tissue images. With the help of transfer learning, classification and segmentation…

Super-resolution ultrasound via microbubble (MB) localisation and tracking, also known as ultrasound localisation microscopy (ULM), can resolve microvasculature beyond the acoustic diffraction limit. However, significant challenges remain…

Radiotherapy treatment for prostate cancer relies on computed tomography (CT) and/or magnetic resonance imaging (MRI) for segmentation of target volumes and organs at risk (OARs). Manual segmentation of these volumes is regarded as the gold…