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Self-supervised learning is crucial for clinical imaging applications, given the lack of explicit labels in healthcare. However, conventional approaches that rely on precise vision-language alignment are not always feasible in complex…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Jielin Qiu , Peide Huang , Makiya Nakashima , Jaehyun Lee , Jiacheng Zhu , Wilson Tang , Pohao Chen , Christopher Nguyen , Byung-Hak Kim , Debbie Kwon , Douglas Weber , Ding Zhao , David Chen

This paper presents a unique approach for the dichotomy between useful and adverse variations of key-point descriptors, namely the identity and the expression variations in the descriptor (feature) space. The descriptors variations are…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Faisal R. Al-Osaimi

Uncertainty estimation, which provides a means of building explainable neural networks for medical imaging applications, have mostly been studied for single deep learning models that focus on a specific task. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Leonhard F. Feiner , Martin J. Menten , Kerstin Hammernik , Paul Hager , Wenqi Huang , Daniel Rueckert , Rickmer F. Braren , Georgios Kaissis

Cardiac left ventricle (LV) quantification provides a tool for diagnosing cardiac diseases. Automatic calculation of all relevant LV indices from cardiac MR images is an intricate task due to large variations among patients and deformation…

Image and Video Processing · Electrical Eng. & Systems 2020-02-04 Nils Gessert , Alexander Schlaefer

A model's ability to express its own predictive uncertainty is an essential attribute for maintaining clinical user confidence as computational biomarkers are deployed into real-world medical settings. In the domain of cancer digital…

MOTIVATION: Left ventricular (LV) hypertrophy is a strong predictor of cardiovascular outcomes, but its genetic regulation remains largely unexplained. Conventional phenotyping relies on manual calculation of LV mass and wall thickness, but…

Uncertainty quantification for deep learning is a challenging open problem. Bayesian statistics offer a mathematically grounded framework to reason about uncertainties; however, approximate posteriors for modern neural networks still…

Machine Learning · Statistics 2020-01-23 Nicolas Brosse , Carlos Riquelme , Alice Martin , Sylvain Gelly , Éric Moulines

The fundamental problem with ultrasound-guided diagnosis is that the acquired images are often 2-D cross-sections of a 3-D anatomy, potentially missing important anatomical details. This limitation leads to challenges in ultrasound…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Ang Nan Gu , Michael Tsang , Hooman Vaseli , Teresa Tsang , Purang Abolmaesumi

Reconstructing 3D human heads in low-view settings presents technical challenges, mainly due to the pronounced risk of overfitting with limited views and high-frequency signals. To address this, we propose geometry decomposition and adopt a…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Baixin Xu , Jiarui Zhang , Kwan-Yee Lin , Chen Qian , Ying He

Deformable image registration is fundamental to longitudinal and population analysis. Geometric alignment of the infant brain MR images is challenging, owing to rapid changes in image appearance in association with brain development. In…

Computer Vision and Pattern Recognition · Computer Science 2020-07-07 Dongming Wei , Sahar Ahmad , Yunzhi Huang , Lei Ma , Zhengwang Wu , Gang Li , Li Wang , Qian Wang , Pew-Thian Yap , Dinggang Shen

We propose to learn a low-dimensional probabilistic deformation model from data which can be used for registration and the analysis of deformations. The latent variable model maps similar deformations close to each other in an encoding…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Julian Krebs , Hervé Delingette , Boris Mailhé , Nicholas Ayache , Tommaso Mansi

The ability of deep learning to predict with uncertainty is recognized as key for its adoption in clinical routines. Moreover, performance gain has been enabled by modelling uncertainty according to empirical evidence. While previous work…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Jiawei Yang , Yuan Liang , Yao Zhang , Weinan Song , Kun Wang , Lei He

In healthcare applications, predictive uncertainty has been used to assess predictive accuracy. In this paper, we demonstrate that predictive uncertainty estimated by the current methods does not highly correlate with prediction error by…

Machine Learning · Computer Science 2021-07-08 Shi Hu , Nicola Pezzotti , Max Welling

Learning data representations under uncertainty is an important task that emerges in numerous scientific computing and data analysis applications. However, uncertainty quantification techniques are computationally intensive and become…

Machine Learning · Computer Science 2025-08-06 Paz Fink Shustin , Shashanka Ubaru , Małgorzata J. Zimoń , Songtao Lu , Vasileios Kalantzis , Lior Horesh , Haim Avron

In computational histopathology algorithms now outperform humans on a range of tasks, but to date none are employed for automated diagnoses in the clinic. Before algorithms can be involved in such high-stakes decisions they need to "know…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Lea Goetz

Registration of pre-operative and post-recurrence brain images is often needed to evaluate the effectiveness of brain gliomas treatment. While recent deep learning-based deformable registration methods have achieved remarkable success with…

Image and Video Processing · Electrical Eng. & Systems 2022-06-09 Tony C. W. Mok , Albert C. S. Chung

Staging of liver fibrosis is important in the diagnosis and treatment planning of patients suffering from liver diseases. Current deep learning-based methods using abdominal magnetic resonance imaging (MRI) usually take a sub-region of the…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Zheyao Gao , Yuanye Liu , Fuping Wu , NanNan Shi , Yuxin Shi , Xiahai Zhuang

Image registration is an ill-posed inverse problem which often requires regularisation on the solution space. In contrast to most of the current approaches which impose explicit regularisation terms such as smoothness, in this paper we…

Image and Video Processing · Electrical Eng. & Systems 2020-07-09 Chen Qin , Shuo Wang , Chen Chen , Huaqi Qiu , Wenjia Bai , Daniel Rueckert

Computational image reconstruction algorithms generally produce a single image without any measure of uncertainty or confidence. Regularized Maximum Likelihood (RML) and feed-forward deep learning approaches for inverse problems typically…

Machine Learning · Computer Science 2020-12-18 He Sun , Katherine L. Bouman

Image-based computational fluid dynamics (CFD) modeling enables derivation of hemodynamic information, which has become a paradigm in cardiovascular research and healthcare. Nonetheless, the predictive accuracy largely depends on precisely…

Fluid Dynamics · Physics 2021-07-20 Han Gao , Xueyu Zhu , Jian-Xun Wang