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Current volumetric biomedical foundation models struggle to generalize as public 3D datasets are small and do not cover the broad diversity of medical procedures, conditions, anatomical regions, and imaging protocols. We address this by…

Whole-heart segmentation from CT and MRI scans is crucial for cardiovascular disease analysis, yet existing methods struggle with modality-specific biases and the need for extensive labeled datasets. To address these challenges, we propose…

The application of self-supervised techniques has become increasingly prevalent within medical visualization tasks, primarily due to its capacity to mitigate the data scarcity prevalent in the healthcare sector. The majority of current…

Head computed tomography (CT) imaging is a widely-used imaging modality with multitudes of medical indications, particularly in assessing pathology of the brain, skull, and cerebrovascular system. It is commonly the first-line imaging in…

Training deep learning models for three-dimensional (3D) medical imaging, such as Computed Tomography (CT), is fundamentally challenged by the scarcity of labeled data. While pre-training on natural images is common, it results in a…

Pathology foundation models learn morphological representations through self-supervised pretraining on large-scale whole-slide images, yet they do not explicitly capture the underlying molecular state of the tissue. Spatial transcriptomics…

Accurate segmentation of pulmonary structures iscrucial in clinical diagnosis, disease study, and treatment planning. Significant progress has been made in deep learning-based segmentation techniques, but most require much labeled data for…

Skin diseases impose a substantial burden on global healthcare systems, driven by their high prevalence (affecting up to 70% of the population), complex diagnostic processes, and a critical shortage of dermatologists in resource-limited…

Volumetric medical image segmentation is pivotal in enhancing disease diagnosis, treatment planning, and advancing medical research. While existing volumetric foundation models for medical image segmentation, such as SAM-Med3D and SegVol,…

This study presents an open-source toolkit to address critical challenges in preprocessing data for self-supervised learning (SSL) for 3D medical imaging, focusing on data privacy and computational efficiency. The toolkit comprises two main…

This thesis works to address a pivotal challenge in medical image analysis: the reliance on extensive labeled datasets, which are often limited due to the need for expert annotation and constrained by privacy and legal issues. By focusing…

Self-supervised learning methods based on data augmentations, such as SimCLR, BYOL, or DINO, allow obtaining semantically meaningful representations of image datasets and are widely used prior to supervised fine-tuning. A recent…

Semi-supervised learning (SSL) has attracted much attention since it reduces the expensive costs of collecting adequate well-labeled training data, especially for deep learning methods. However, traditional SSL is built upon an assumption…

Since large number of high-quality remote sensing images are readily accessible, exploiting the corpus of images with less manual annotation draws increasing attention. Self-supervised models acquire general feature representations by…

Recent advances in self-supervised learning (SSL) have made it possible to learn general-purpose visual features that capture both the high-level semantics and the fine-grained spatial structure of images. Most notably, the recent DINOv2…

In this study, we present a multimodal framework for predicting neuro-facial disorders by capturing both vocal and facial cues. We hypothesize that explicitly disentangling shared and modality-specific representations within multimodal…

Recent advances in deep learning methods have come to define the state-of-the-art for many medical imaging applications, surpassing even human judgment in several tasks. Those models, however, when trained to reduce the empirical risk on a…

Due to the scarcity of labeled data, self-supervised learning (SSL) has gained much attention in 3D medical image segmentation, by extracting semantic representations from unlabeled data. Among SSL strategies, Masked image modeling (MIM)…

Tissue phenotyping is a fundamental task in learning objective characterizations of histopathologic biomarkers within the tumor-immune microenvironment in cancer pathology. However, whole-slide imaging (WSI) is a complex computer vision in…

Privacy-preserving and secure data sharing are critical for medical image analysis while maintaining accuracy and minimizing computational overhead are also crucial. Applying existing deep neural networks (DNNs) to encrypted medical data is…