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In this paper, we tackle the domain adaptive object detection problem, where the main challenge lies in significant domain gaps between source and target domains. Previous work seeks to plainly align image-level and instance-level shifts to…

Computer Vision and Pattern Recognition · Computer Science 2020-03-23 Chang-Dong Xu , Xing-Ran Zhao , Xin Jin , Xiu-Shen Wei

Deep learning has produced state-of-the-art results for a variety of tasks. While such approaches for supervised learning have performed well, they assume that training and testing data are drawn from the same distribution, which may not…

Machine Learning · Computer Science 2020-02-10 Garrett Wilson , Diane J. Cook

We present an algorithm that learns representations which explicitly compensate for domain mismatch and which can be efficiently realized as linear classifiers. Specifically, we form a linear transformation that maps features from the…

Machine Learning · Computer Science 2017-11-10 Judy Hoffman , Erik Rodner , Jeff Donahue , Trevor Darrell , Kate Saenko

Human beings can quickly adapt to environmental changes by leveraging learning experience. However, the poor ability of adapting to dynamic environments remains a major challenge for AI models. To better understand this issue, we study the…

Computer Vision and Pattern Recognition · Computer Science 2020-07-28 Peng Su , Shixiang Tang , Peng Gao , Di Qiu , Ni Zhao , Xiaogang Wang

Significant advances have been made towards building accurate automatic segmentation systems for a variety of biomedical applications using machine learning. However, the performance of these systems often degrades when they are applied on…

Semantic segmentation with dense pixel-wise annotation has achieved excellent performance thanks to deep learning. However, the generalization of semantic segmentation in the wild remains challenging. In this paper, we address the problem…

Computer Vision and Pattern Recognition · Computer Science 2020-09-29 Wei Zhou , Yukang Wang , Jiajia Chu , Jiehua Yang , Xiang Bai , Yongchao Xu

Cellular nuclei recognition serves as a fundamental and essential step in the workflow of digital pathology. However, with disparate source organs and staining procedures among histology image clusters, the scanned tiles inherently conform…

Quantitative Methods · Quantitative Biology 2024-07-22 Jianan Fan , Dongnan Liu , Canran Li , Hang Chang , Heng Huang , Filip Braet , Mei Chen , Weidong Cai

In this work, we propose a mutual information (MI) based unsupervised domain adaptation (UDA) method for the cross-domain nuclei segmentation. Nuclei vary substantially in structure and appearances across different cancer types, leading to…

Computer Vision and Pattern Recognition · Computer Science 2022-06-30 Yash Sharma , Sana Syed , Donald E. Brown

Domain adaptation manages to transfer the knowledge of well-labeled source data to unlabeled target data. Many recent efforts focus on improving the prediction accuracy of target pseudo-labels to reduce conditional distribution shift. In…

Machine Learning · Computer Science 2023-02-20 Lei Tian , Yongqiang Tang , Liangchen Hu , Wensheng Zhang

Adapting machine learning models to medical time series across different domains remains a challenge due to complex temporal dependencies and dynamic distribution shifts. Current approaches often focus on isolated feature representations,…

Machine Learning · Computer Science 2025-09-23 YongKyung Oh , Alex Bui

Motivation. Understanding the pan-cancer mutational landscape offers critical insights into the molecular mechanisms underlying tumorigenesis. While patient-level machine learning techniques have been widely employed to identify tumor…

Machine Learning · Computer Science 2025-08-29 Yifan Dou , Adam Khadre , Ruben C Petreaca , Golrokh Mirzaei

The cost of large scale data collection and annotation often makes the application of machine learning algorithms to new tasks or datasets prohibitively expensive. One approach circumventing this cost is training models on synthetic data…

Computer Vision and Pattern Recognition · Computer Science 2016-08-23 Konstantinos Bousmalis , George Trigeorgis , Nathan Silberman , Dilip Krishnan , Dumitru Erhan

Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…

Image and Video Processing · Electrical Eng. & Systems 2023-08-09 Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

The study of histopathological subtypes is valuable for the personalisation of effective treatment strategies for ovarian cancer. However, increasing diagnostic workloads present a challenge for UK pathology departments, leading to the rise…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Marcus Jenkins , Jasenka Mazibrada , Bogdan Leahu , Michal Mackiewicz

Domain adaptation is an attractive approach given the availability of a large amount of labeled data with similar properties but different domains. It is effective in image classification tasks where obtaining sufficient label data is…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Yeganeh Madadi , Vahid Seydi , Jian Sun , Edward Chaum , Siamak Yousefi

The clinical management of breast cancer depends on an accurate understanding of the tumor and its anatomical context to adjacent tissues and landmark structures. This context may be provided by semantic segmentation methods; however,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Arda Pekis , Vignesh Kannan , Evandros Kaklamanos , Anu Antony , Snehal Patel , Tyler Earnest

Recent works on domain adaptation reveal the effectiveness of adversarial learning on filling the discrepancy between source and target domains. However, two common limitations exist in current adversarial-learning-based methods. First,…

Computer Vision and Pattern Recognition · Computer Science 2019-12-05 Minghao Xu , Jian Zhang , Bingbing Ni , Teng Li , Chengjie Wang , Qi Tian , Wenjun Zhang

Artificial intelligence and medicine have a longstanding and proficuous relationship. In the present work we develop a brief assessment of this relationship with specific focus on machine learning, in which we highlight some critical points…

Artificial Intelligence · Computer Science 2018-11-13 Flavio S Correa da Silva , Frederico P Costa , Antonio F Iemma

Unsupervised domain adaptation (UDA) is a pivotal form in machine learning to extend the in-domain model to the distinctive target domains where the data distributions differ. Most prior works focus on capturing the inter-domain…

Computer Vision and Pattern Recognition · Computer Science 2023-10-30 Zhiqing Xiao , Haobo Wang , Ying Jin , Lei Feng , Gang Chen , Fei Huang , Junbo Zhao

Computer aided pathological analysis has been the gold standard for tumor diagnosis, however domain shift is a significant problem in histopathology. It may be caused by variability in anatomical structures, tissue preparation, and imaging…

Image and Video Processing · Electrical Eng. & Systems 2024-09-25 Abdul Qayyum , Moona Mazher Imran Razzak , Steven A Niederer