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Biological signaling is imagined as a combination of activation and transport. The former is triggered by local molecular interactions and the latter is the result of molecular diffusion. However, other fundamental physical principles of…

Biological Physics · Physics 2016-12-07 Bernhard Fichtl , Matthias F. Schneider

These lecture notes are designed to provide a brief introduction into the phenomenology of active matter and to present some of the analytical tools used to rationalize the emergent behavior of active systems. Such systems are made of…

Soft Condensed Matter · Physics 2018-07-02 Étienne Fodor , M. Cristina Marchetti

We introduce a stochastic model of coupled genetic oscillators in which chains of chemical events involved in gene regulation and expression are represented as sequences of Poisson processes. We characterize steady states by their…

Biological Physics · Physics 2018-03-28 David J. Jörg , Luis G. Morelli , Frank Jülicher

Morphogenetic dynamics of tissue sheets require coordinated cell shape changes regulated by global patterning of mechanical forces. Inspired by such biological phenomena, we propose a minimal mechanochemical model based on the notion that…

Soft Condensed Matter · Physics 2021-01-01 Andrei Zakharov , Kinjal Dasbiswas

We introduce a generic, purely mechanical model for environment sensitive motion of mammalian cells that is applicable to chemotaxis, haptotaxis, and durotaxis as modes of motility. It is able to theoretically explain all relevant…

Cell Behavior · Quantitative Biology 2016-05-09 Patrick Bitter , Kristof Leon Beck , Peter Lenz

Chemotaxis is a directed cell movement in response to external chemical stimuli. In this paper, we propose a simple model for the origin of chemotaxis - namely how a directed movement in response to an external chemical signal may occur…

Analysis of PDEs · Mathematics 2023-06-30 Yishu Gong , Alexander Kiselev

Coupling between spatially separated magnets can be mediated by excitations such as photons and phonons, which can be characterized as coherent coupling and dissipative coupling with real and imaginary coupling rate. We theoretically…

Mesoscale and Nanoscale Physics · Physics 2023-03-13 Weichao Yu

We discuss recent progress in the theoretical description of chemotaxis by coupling the diffusion equation of a chemical species to equations describing the motion of sensing microorganisms. In particular, we discuss models for…

Soft Condensed Matter · Physics 2019-02-05 B. Liebchen , H. Löwen

Here we demonstrate a synthetic micro-engine, based on long-range controlled movement of colloidal particles, which is induced by a local catalytic reaction. The directed motion at long timescales was achieved by placing specially designed…

Statistical Mechanics · Physics 2008-07-16 Larysa Baraban , Christian Kreidler , Denys Makarov , Paul Leiderer , Artur Erbe

Most computer simulations of molecular dynamics take place under equilibrium conditions--in a closed, isolated system, or perhaps one held at constant temperature or pressure. Sometimes, extra tensions, shears, or temperature gradients are…

Statistical Mechanics · Physics 2022-05-25 Alex Albaugh , Todd R. Gingrich

This paper addresses the decomposition of biochemical networks into functional modules that preserve their dynamic properties upon interconnection with other modules, which permits the inference of network behavior from the properties of…

Molecular Networks · Quantitative Biology 2014-12-03 Hari Sivakumar , Stephen R. Proulx , João P. Hespanha

The large scale behaviour of a population of cells that grow and interact through the concentration field of the chemicals they secrete is studied using dynamical renormalization group methods. The combination of the effective long-range…

Cell Behavior · Quantitative Biology 2015-01-19 Anatolij Gelimson , Ramin Golestanian

Molecular dynamics simulations use statistical mechanics at the atomistic scale to enable both the elucidation of fundamental mechanisms and the engineering of matter for desired tasks. The behavior of molecular systems at the microscale is…

Computational Physics · Physics 2020-12-25 Wujie Wang , Simon Axelrod , Rafael Gómez-Bombarelli

A number of microorganisms leave persistent trails while moving along surfaces. For single-cell organisms, the trail-mediated self-interaction will influence its dynamics. It has been discussed recently [Kranz \textit{et al.} Phys. Rev.…

Biological Physics · Physics 2019-06-07 W. Till Kranz , Ramin Golestanian

Electrical signals play the primary role in rapid communication among organs, tissues and cells in biosystems. We have analyzed and discussed three phenomena of electrical communication in biosystems, including direction-changing movement…

Biological Physics · Physics 2017-08-11 Jingjing Xu , Fan Yang , Danhong Han , Shengyong Xu

A chemo-mechanical model for a finite-strain elasto-viscoplastic material containing multiple chemical components is formulated and an efficient numerical implementation is developed to solve the resulting transport relations. The numerical…

Computational Physics · Physics 2020-04-22 Pratheek Shanthraj , Chuanlai Liu , Amirhassan Akbarian , Bob Svendsen , Dierk Raabe

Current developments in molecular electronics, motors and chemical sensors could enable constructing large numbers of devices able to sense, compute and act in micron-scale environments. Such microscopic machines, of sizes comparable to…

Robotics · Computer Science 2023-02-03 Tad Hogg

Cell motility is one of the most fundamental phenomena underlying biological processes that maintain living organisms alive. Here we introduce a simple model to describe the motility of cells which include not only time-correlated internal…

Biological Physics · Physics 2022-07-13 T. N. Azevedo , L. G. Rizzi

Pulsatory activity patterns, driven by mechanochemical feedback, are prevalent in many biological systems. Here we present a theoretical framework to elucidate the mechanical origin and regulation of pulsatile activity patterns within…

Biological Physics · Physics 2023-10-10 Fernanda Pérez-Verdugo , Samuel Banks , Shiladitya Banerjee

The dynamical systems found in Nature are rarely isolated. Instead they interact and influence each other. The coupling functions that connect them contain detailed information about the functional mechanisms underlying the interactions and…

Adaptation and Self-Organizing Systems · Physics 2017-11-15 Tomislav Stankovski , Tiago Pereira , Peter V. E. McClintock , Aneta Stefanovska