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Photon-counting computed tomography (PCCT) with energy discrimination capabilities hold great potentials to improve the limitations of the conventional CT, including better signal-to-noise ratio (SNR), improved contrast-to-noise ratio…
Purpose: To evaluate a proposed method to reconstruct CT numbers that accurately mimic conventional CT numbers from spectral CT data, as would have been produced by a conventional system without effects of beam hardening. Approach: We…
Purpose: Spectral imaging is a method in medical x-ray imaging to extract information about the object constituents by the material-specific energy dependence of x-ray attenuation. The authors have investigated a photon-counting spectral…
As photon counting detectors are being explored for medical and industrial imaging applications, there is a critical need to understand spectral characteristics of scattered x-ray photons. Scattered radiation is detrimental to x-ray imaging…
Purpose: Photon counting (PC) computed tomography (CT) can provide material selective CT imaging at lowest patient dose but it suffers from suboptimal count rate. A dynamic beam attenuator (DBA) can help with count rate by modulating x-ray…
PET requires accurate, precise, and efficient scatter correction techniques. Conventional scatter estimation typically relies on tail-fitted single-scatter simulation (SSS) strategy. However, the accuracy of tail-fitted SSS is limited, for…
Photon-counting computed tomography has demonstrated significant advancements in recent years; however, micro photon-counting CT (Micro-PCCT) systems are still limited by pixel-wise detector response nonuniformity, which degrades…
An important question when developing photon-counting detectors for computed tomography is how to select energy thresholds. In this work thresholds are optimized by maximizing signal-difference-to-noise ratio squared (SDNR2) in an optimally…
Photon-counting computed tomography (PCCT) marks a significant advancement over conventional energy-integrating detector (EID) CT systems. This review highlights PCCT's superior spatial and contrast resolution, reduced radiation dose, and…
Photon-counting spectral computed tomography is now clinically available. These new detectors come with the promise of higher contrast-to-noise ratio and spatial resolution and improved low-dose imaging. However, one important design…
We propose an experimental methodology for probing the energy barrier inhomogeneity at the metal/semiconductor interface without the need for time-consuming microscopic survey. It is based on the known statistical nature of the interfacial…
Scatter can account for large errors in cone-beam CT (CBCT) due to its wide field of view, and its complicated nature makes its compensation difficult. Iterative polyenergetic reconstruction algorithms offer the potential to provide…
In a neutrinoless double-beta decay ($0\nu\beta\beta$) experiment, energy resolution is important to distinguish between $0\nu\beta\beta$ and background events. CAlcium fluoride for studies of Neutrino and Dark matters by Low Energy…
Single Photon Emission Computed Tomography (SPECT) is one of the nuclear medicine imaging modalities used for functional analysis of animal and human organs. Gamma rays emitted from the scanned body are filtered with collimators and…
Compared with the start-of-art energy integration detectors (EIDs), photon-counting detectors (PCDs) with energy discrimination capabilities have demonstrated great potentials in various applications of medical x-ray radiography and…
Many clinical applications depend critically on the accurate differentiation and classification of different types of materials in patient anatomy. This work introduces a unified framework for accurate nonlinear material decomposition and…
Magnetic resonance imaging (MRI) based electrical properties tomography (EPT) is the quantification of the conductivity and permittivity of different tissues. These electrical properties can be obtained through different reconstruction…
With the steadily improving sensitivity afforded by current and future galaxy surveys, a robust extraction of two-point correlation function measurements may become increasingly hampered by the presence of astrophysical foregrounds or…
A model-independent method is proposed to characterize and correct charge sharing spectral distortions in energy-resolved X-ray acquisitions with pixellated photon-counting detectors. The technique is based on the determination of a…
We compute electromagnetic radiative corrections in the inverse beta decay, $\bar{\nu}_e + p \rightarrow e^+ + n$, at reactor antineutrino energies within the heavy baryon chiral perturbation theory, provide the most accurate cross-section…