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In recent years, near-term noisy intermediate scale quantum (NISQ) computing devices have become available. One of the most promising application areas to leverage such NISQ quantum computer prototypes is quantum machine learning. While…

Quantum Physics · Physics 2021-08-31 Dániel Nagy , Zsolt Tabi , Péter Hága , Zsófia Kallus , Zoltán Zimborás

Hybrid quantum-classical neural networks (HQNNs) are emerging as a practical approach for quantum machine learning in the noisy intermediate-scale quantum (NISQ) era, as they combine classical learning components with parameterized quantum…

Quantum Physics · Physics 2026-05-19 Alberto Marchisio , Muhammad Kashif , Nouhaila Innan , Muhammad Shafique

Combinatorial optimization problems are ubiquitous and computationally hard to solve in general. Quantum approximate optimization algorithm (QAOA), one of the most representative quantum-classical hybrid algorithms, is designed to solve…

Quantum Physics · Physics 2024-03-12 Lixue Cheng , Yu-Qin Chen , Shi-Xin Zhang , Shengyu Zhang

One of the main challenges in drug discovery is to find molecules that bind specifically and strongly to their target protein while having minimal binding to other proteins. By predicting binding affinity, it is possible to identify the…

Quantum Physics · Physics 2023-01-19 L. Domingo , M. Djukic , C. Johnson , F. Borondo

Quantum computing has promised significant improvement in solving difficult computational tasks over classical computers. Designing quantum circuits for practical use, however, is not a trivial objective and requires expert-level knowledge.…

Quantum Physics · Physics 2021-12-14 Esther Ye , Samuel Yen-Chi Chen

Quantum Architecture Search (QAS) is an emerging field aimed at automating the design of quantum circuits for optimal performance. This paper introduces a novel QAS framework employing hybrid quantum reinforcement learning with quantum…

Quantum Physics · Physics 2025-12-05 Siddhant Dutta , Nouhaila Innan , Sadok Ben Yahia , Muhammad Shafique

A key open question in quantum computing is whether quantum algorithms can potentially offer a significant advantage over classical algorithms for tasks of practical interest. Understanding the limits of classical computing in simulating…

Quantum Physics · Physics 2021-06-23 Matija Medvidovic , Giuseppe Carleo

As quantum computing advances, quantum approximate optimization algorithms (QAOA) have shown promise in addressing combinatorial optimization problems. However, the limitations of Noisy Intermediate Scale Quantum (NISQ) devices hinder the…

Optimization theory has been widely studied in academia and finds a large variety of applications in industry. The different optimization models in their discrete and/or continuous settings have catered to a rich source of research…

Quantum Physics · Physics 2026-03-16 Debbie Lim , Joao F. Doriguello , Patrick Rebentrost

Developing state-of-the-art classical simulators of quantum circuits is of utmost importance to test and evaluate early quantum technology and understand the true potential of full-blown error-corrected quantum computers. In the past few…

Quantum Physics · Physics 2022-01-03 Salvatore Mandrà , Jeffrey Marshall , Eleanor G. Rieffel , Rupak Biswas

Quantum error correction is one of the fundamental building blocks of digital quantum computation. The Quantum Lego formalism has introduced a systematic way of constructing new stabilizer codes out of basic lego-like building blocks, which…

Quantum Physics · Physics 2026-01-14 Yariv Yanay

Variational quantum algorithms provide a direct, physics-based approach to protein structure prediction, but their accuracy is limited by the coarse resolution of the energy landscapes generated on current noisy devices. We propose a hybrid…

Emerging Technologies · Computer Science 2025-10-09 Yuqi Zhang , Yuxin Yang , Feixiong Chen , Cheng-Chang Lu , Nima Saeidi , Samuel L. Volchenboum , Junhan Zhao , Siwei Chen , Weiwen Jiang , Qiang Guan

Recent one-shot Neural Architecture Search algorithms rely on training a hardware-agnostic super-network tailored to a specific task and then extracting efficient sub-networks for different hardware platforms. Popular approaches separate…

Machine Learning · Computer Science 2023-12-22 Sharath Nittur Sridhar , Maciej Szankin , Fang Chen , Sairam Sundaresan , Anthony Sarah

We present a collection of optimizers tuned for usage on Noisy Intermediate-Scale Quantum (NISQ) devices. Optimizers have a range of applications in quantum computing, including the Variational Quantum Eigensolver (VQE) and Quantum…

Quantum Physics · Physics 2021-04-16 Wim Lavrijsen , Ana Tudor , Juliane Müller , Costin Iancu , Wibe de Jong

This work investigates the performance of a Hybrid Quantum Genetic Algorithm (HQGA) compared to a classical Genetic Algorithm (GA) for solving the portfolio optimization problem. Our results indicate that the HQGA converges faster to the…

Designing neural architectures is a fundamental step in deep learning applications. As a partner technique, model compression on neural networks has been widely investigated to gear the needs that the deep learning algorithms could be run…

Computer Vision and Pattern Recognition · Computer Science 2018-11-26 Yukang Chen , Gaofeng Meng , Qian Zhang , Xinbang Zhang , Liangchen Song , Shiming Xiang , Chunhong Pan

Variational quantum algorithms such as the Quantum Approximation Optimization Algorithm (QAOA) in recent years have gained popularity as they provide the hope of using NISQ devices to tackle hard combinatorial optimization problems. It is,…

Quantum Physics · Physics 2024-02-07 Yash J. Patel , Sofiene Jerbi , Thomas Bäck , Vedran Dunjko

This paper introduces a hybrid framework for portfolio optimization that fuses Long Short-Term Memory (LSTM) forecasting with a Proximal Policy Optimization (PPO) reinforcement learning strategy. The proposed system leverages the predictive…

Machine Learning · Computer Science 2025-11-25 Jun Kevin , Pujianto Yugopuspito

We apply a hybrid evolutionary algorithm to minimize the depth of circuits in quantum computing. More specifically, we evaluate two different variants of the algorithm. In the first approach, we combine the evolutionary algorithm with an…

We develop a quantum-classical hybrid algorithm for function optimization that is particularly useful in the training of neural networks since it makes use of particular aspects of high-dimensional energy landscapes. Due to a recent…

Quantum Physics · Physics 2017-10-20 Leonard Wossnig , Sebastian Tschiatschek , Stefan Zohren
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