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Metal-organic frameworks (MOFs) are nanoporous compounds composed of metal ions and organic linkers. MOFs play an important role in industrial applications such as gas separation, gas purification, and electrolytic catalysis. Important MOF…

Machine Learning · Computer Science 2020-11-02 Shehtab Zaman , Christopher Owen , Kenneth Chiu , Michael Lawler

Designing metal-organic frameworks (MOFs) with novel chemistries is a longstanding challenge due to their large combinatorial space and complex 3D arrangements of the building blocks. While recent deep generative models have enabled…

Biomolecules · Quantitative Biology 2026-02-05 Nayoung Kim , Seongsu Kim , Sungsoo Ahn

Identifying optimal synthesis conditions for metal-organic frameworks (MOFs) is a major challenge that can serve as a bottleneck for new materials discovery and development. Trial-and-error approach that relies on a chemist's intuition and…

Materials Science · Physics 2021-09-01 Hyunsoo Park , Yeonghun Kang , Wonyoung Choe , Jihan Kim

Metal-organic frameworks (MOFs) marry inorganic nodes, organic edges, and topological nets into programmable porous crystals, yet their astronomical design space defies brute-force synthesis. Generative modeling holds ultimate promise, but…

Chemical Physics · Physics 2025-05-14 Chenru Duan , Aditya Nandy , Sizhan Liu , Yuanqi Du , Liu He , Yi Qu , Haojun Jia , Jin-Hu Dou

Metal-Organic Frameworks (MOFs) are materials with a high degree of porosity that can be used for applications in energy storage, water desalination, gas storage, and gas separation. However, the chemical space of MOFs is close to an…

Machine Learning · Computer Science 2022-10-26 Zhonglin Cao , Rishikesh Magar , Yuyang Wang , Amir Barati Farimani

Generative AI poses both opportunities and risks for solving inverse design problems in the sciences. Generative tools provide the ability to expand and refine a search space autonomously, but do so at the cost of exploring low-quality…

Machine Learning · Computer Science 2025-10-01 Marcus Schwarting , Logan Ward , Nathaniel Hudson , Xiaoli Yan , Ben Blaiszik , Santanu Chaudhuri , Eliu Huerta , Ian Foster

The large number of possible structures of metal-organic frameworks (MOFs) and their limitless potential applications has motivated molecular modelers and researchers to develop methods and models to efficiently assess MOF performance. Some…

Materials Science · Physics 2021-10-04 Krishnendu Mukherjee , Alexander W. Dowling , Yamil Colón

The increasing CO2 level is a critical concern and suitable materials are needed to capture such gases from the environment. While experimental and conventional computational methods are useful in finding such materials, they are usually…

AI technologies are moving rapidly from research to production. With the popularity of Foundation Models (FMs) that generate text, images, and video, AI-based systems are increasing their complexity. Compared to traditional AI-based…

Software Engineering · Computer Science 2024-12-03 Orlando Marquez Ayala , Patrice Béchard

Metal-organic frameworks (MOFs) are highly promising for carbon capture, yet navigating their vast design space remains challenging. Recent deep generative models enable de novo MOF design but primarily act as feed-forward structure…

Machine Learning · Computer Science 2026-04-16 Chaoran Zhang , Guangyao Li , Dongxu Ji

Materials discovery is fundamental to advance next-generation technologies as well as for sustainable and circular economy. Beyond computational screening, generative models are efficient at finding materials with desired properties, via…

Metal-organic frameworks (MOFs) have been widely investigated for challenging catalytic transformations due to their well-defined structures and high degree of synthetic tunability. These features, at least in principle, make MOFs ideally…

Materials Science · Physics 2021-10-19 Andrew S. Rosen , Justin M. Notestein , Randall Q. Snurr

The removal of leaked radioactive iodine isotopes in humid environments holds significant importance in nuclear waste management and nuclear accident mitigation. In this study, high-throughput computational screening and machine learning…

Machine Learning · Computer Science 2025-04-29 Haoyi Tan , Yukun Teng , Guangcun Shan

In this work, we pursue a unified paradigm for multimodal pretraining to break the scaffolds of complex task/modality-specific customization. We propose OFA, a Task-Agnostic and Modality-Agnostic framework that supports Task…

Computer Vision and Pattern Recognition · Computer Science 2022-06-02 Peng Wang , An Yang , Rui Men , Junyang Lin , Shuai Bai , Zhikang Li , Jianxin Ma , Chang Zhou , Jingren Zhou , Hongxia Yang

Short-chain per- and polyfluoroalkyl substances (PFASs) are increasingly replacing regulated long-chain PFASs, yet they remain challenging to remove from water due to their high persistence, mobility, and weak affinity toward conventional…

Materials Science · Physics 2026-03-17 Mengru Zhang , Satyanarayana Bonakala , Taku Watanabe , Karim Hamzaoui , Guillaume Maurin

ChatMOF is an autonomous Artificial Intelligence (AI) system that is built to predict and generate metal-organic frameworks (MOFs). By leveraging a large-scale language model (GPT-4 and GPT-3.5-turbo), ChatMOF extracts key details from…

Computation and Language · Computer Science 2023-08-28 Yeonghun Kang , Jihan Kim

Designing large-scale geological carbon capture and storage projects and ensuring safe long-term CO2 containment - as a climate change mitigation strategy - requires fast and accurate numerical simulations. These simulations involve solving…

Mathematical Software · Computer Science 2023-04-25 Ryuichi Sai , Mathias Jacquelin , François P. Hamon , Mauricio Araya-Polo , Randolph R. Settgast

Coarse-Grained Reconfigurable Arrays (CGRAs) hold great promise as power-efficient edge accelerator, offering versatility beyond AI applications. Morpher, an open-source, architecture-adaptive CGRA design framework, is specifically designed…

Hardware Architecture · Computer Science 2023-09-13 Dhananjaya Wijerathne , Zhaoying Li , Tulika Mitra

Recent advances in generative AI have brought incredible breakthroughs in several areas, including medical imaging. These generative models have tremendous potential not only to help safely share medical data via synthetic datasets but also…

Deep generative models have shown promise for modeling metal-organic frameworks (MOFs), but existing approaches (1) rely on coarse-grained representations that assume fixed bond lengths and angles, and (2) neglect the MOF-adsorbate…

Materials Science · Physics 2026-02-10 Nayoung Kim , Honghui Kim , Sihyun Yu , Minkyu Kim , Seongsu Kim , Sungsoo Ahn