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Recent work utilizes Large Language Models (LLMs) for topic modeling, generating comprehensible topic labels for given documents. However, their performance has mainly been evaluated qualitatively, and there remains room for quantitative…

Computation and Language · Computer Science 2024-06-26 Tomoki Doi , Masaru Isonuma , Hitomi Yanaka

Analyzing texts such as open-ended responses, headlines, or social media posts is a time- and labor-intensive process highly susceptible to bias. LLMs are promising tools for text analysis, using either a predefined (top-down) or a…

Human evaluation remains the gold standard for evaluating outputs of Large Language Models (LLMs). The current evaluation paradigm reviews numerous individual responses, leading to significant scalability challenges. LLM outputs can be more…

Human-Computer Interaction · Computer Science 2025-12-12 Junhyeong Hwangbo , Soohyun Lee , Minsoo Cheong , Hyeon Jeon , Jinwook Seo

Due to the implement of guardrails by developers, Large language models (LLMs) have demonstrated exceptional performance in explicit bias tests. However, bias in LLMs may occur not only explicitly, but also implicitly, much like humans who…

Computation and Language · Computer Science 2025-03-05 Xinru Lin , Luyang Li

The training data of large language models (LLMs) comprises a wide range of biomedical literature, reflecting data from many different patient populations. We investigate how it might be possible to recover information on correlation and…

Machine Learning · Computer Science 2026-05-08 Fabian Kabus , Kian Kordtomeikel , Thomas Brox , Heinz Wiendl , Daiana Stolz , Harald Binder

In recent years, Large Language Models (LLMs) have become widely used in medical applications, such as clinical decision support, medical education, and medical question answering. Yet, these models are often English-centric, limiting their…

Computation and Language · Computer Science 2026-02-06 Chaimae Abouzahir , Congbo Ma , Nizar Habash , Farah E. Shamout

Large language models (LLMs) have demonstrated remarkable capabilities for medical question answering and programming, but their potential for generating interpretable computable phenotypes (CPs) is under-explored. In this work, we…

Machine Learning · Computer Science 2025-08-08 Guilherme Seidyo Imai Aldeia , Daniel S. Herman , William G. La Cava

Hallucinations in large language models (LLMs) during summarization of patient-clinician dialogues pose significant risks to patient care and clinical decision-making. However, the phenomenon remains understudied in the clinical domain,…

Large Language Models (LLMs) demonstrate an impressive capacity to recall a vast range of factual knowledge. However, understanding their underlying reasoning and internal mechanisms in exploiting this knowledge remains a key research area.…

Computation and Language · Computer Science 2024-08-07 Marco Bronzini , Carlo Nicolini , Bruno Lepri , Jacopo Staiano , Andrea Passerini

Recent advances in large language models (LLMs) have shown potential in clinical text summarization, but their ability to handle long patient trajectories with multi-modal data spread across time remains underexplored. This study…

Computation and Language · Computer Science 2025-09-08 Maya Kruse , Shiyue Hu , Nicholas Derby , Yifu Wu , Samantha Stonbraker , Bingsheng Yao , Dakuo Wang , Elizabeth Goldberg , Yanjun Gao

Knowledge of the medical decision process, which can be modeled as medical decision trees (MDTs), is critical to build clinical decision support systems. However, the current MDT construction methods rely heavily on time-consuming and…

Computation and Language · Computer Science 2024-01-05 Wei Zhu , Wenfeng Li , Xing Tian , Pengfei Wang , Xiaoling Wang , Jin Chen , Yuanbin Wu , Yuan Ni , Guotong Xie

Large language models (LLMs) have achieved a degree of success in generating coherent and contextually relevant text, yet they remain prone to a significant challenge known as hallucination: producing information that is not substantiated…

Computation and Language · Computer Science 2024-10-28 Ray Li , Tanishka Bagade , Kevin Martinez , Flora Yasmin , Grant Ayala , Michael Lam , Kevin Zhu

Despite the recent advancement in large language models (LLMs) and their high performances across numerous benchmarks, recent research has unveiled that LLMs suffer from hallucinations and unfaithful reasoning. This work studies a specific…

Computation and Language · Computer Science 2024-04-09 Bangzheng Li , Ben Zhou , Fei Wang , Xingyu Fu , Dan Roth , Muhao Chen

Large language models (LLMs), including ChatGPT, Bard, and Llama, have achieved remarkable successes over the last two years in a range of different applications. In spite of these successes, there exist concerns that limit the wide…

Computation and Language · Computer Science 2024-01-17 Junliang Luo , Tianyu Li , Di Wu , Michael Jenkin , Steve Liu , Gregory Dudek

The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…

Computation and Language · Computer Science 2024-07-19 Alexander R. Pelletier , Joseph Ramirez , Irsyad Adam , Simha Sankar , Yu Yan , Ding Wang , Dylan Steinecke , Wei Wang , Peipei Ping

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Chao Ding , Mouxiao Bian , Pengcheng Chen , Hongliang Zhang , Tianbin Li , Lihao Liu , Jiayuan Chen , Zhuoran Li , Yabei Zhong , Yongqi Liu , Haiqing Huang , Dongming Shan , Junjun He , Jie Xu

The potential of large language models (LLMs) to mitigate the time- and cost- related challenges associated with inductive thematic analysis (ITA) has been extensively explored in the literature. However, the use of LLMs to support ITA has…

Human-Computer Interaction · Computer Science 2025-04-01 Muhammad Talal Khalid , Ann-Perry Witmer

Large language models (LLMs) are emerging as promising tools for mental health care, offering scalable support through their ability to generate human-like responses. However, the effectiveness of these models in clinical settings remains…

Artificial Intelligence · Computer Science 2024-08-22 Yining Hua , Hongbin Na , Zehan Li , Fenglin Liu , Xiao Fang , David Clifton , John Torous

Large Language Models (LLMs) have gained significant popularity for their impressive performance across diverse fields. However, LLMs are prone to hallucinate untruthful or nonsensical outputs that fail to meet user expectations in many…

Computation and Language · Computer Science 2023-11-23 Tianhang Zhang , Lin Qiu , Qipeng Guo , Cheng Deng , Yue Zhang , Zheng Zhang , Chenghu Zhou , Xinbing Wang , Luoyi Fu

Large Language Models (LLMs) gain substantial reasoning and decision-making capabilities from thought structures. However, existing methods such as Tree of Thought and Retrieval Augmented Thoughts often fall short in complex tasks due to…

Computation and Language · Computer Science 2024-12-24 Jinghan Zhang , Xiting Wang , Weijieying Ren , Lu Jiang , Dongjie Wang , Kunpeng Liu