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Recent work utilizes Large Language Models (LLMs) for topic modeling, generating comprehensible topic labels for given documents. However, their performance has mainly been evaluated qualitatively, and there remains room for quantitative…
Analyzing texts such as open-ended responses, headlines, or social media posts is a time- and labor-intensive process highly susceptible to bias. LLMs are promising tools for text analysis, using either a predefined (top-down) or a…
Human evaluation remains the gold standard for evaluating outputs of Large Language Models (LLMs). The current evaluation paradigm reviews numerous individual responses, leading to significant scalability challenges. LLM outputs can be more…
Due to the implement of guardrails by developers, Large language models (LLMs) have demonstrated exceptional performance in explicit bias tests. However, bias in LLMs may occur not only explicitly, but also implicitly, much like humans who…
The training data of large language models (LLMs) comprises a wide range of biomedical literature, reflecting data from many different patient populations. We investigate how it might be possible to recover information on correlation and…
In recent years, Large Language Models (LLMs) have become widely used in medical applications, such as clinical decision support, medical education, and medical question answering. Yet, these models are often English-centric, limiting their…
Large language models (LLMs) have demonstrated remarkable capabilities for medical question answering and programming, but their potential for generating interpretable computable phenotypes (CPs) is under-explored. In this work, we…
Hallucinations in large language models (LLMs) during summarization of patient-clinician dialogues pose significant risks to patient care and clinical decision-making. However, the phenomenon remains understudied in the clinical domain,…
Large Language Models (LLMs) demonstrate an impressive capacity to recall a vast range of factual knowledge. However, understanding their underlying reasoning and internal mechanisms in exploiting this knowledge remains a key research area.…
Recent advances in large language models (LLMs) have shown potential in clinical text summarization, but their ability to handle long patient trajectories with multi-modal data spread across time remains underexplored. This study…
Knowledge of the medical decision process, which can be modeled as medical decision trees (MDTs), is critical to build clinical decision support systems. However, the current MDT construction methods rely heavily on time-consuming and…
Large language models (LLMs) have achieved a degree of success in generating coherent and contextually relevant text, yet they remain prone to a significant challenge known as hallucination: producing information that is not substantiated…
Despite the recent advancement in large language models (LLMs) and their high performances across numerous benchmarks, recent research has unveiled that LLMs suffer from hallucinations and unfaithful reasoning. This work studies a specific…
Large language models (LLMs), including ChatGPT, Bard, and Llama, have achieved remarkable successes over the last two years in a range of different applications. In spite of these successes, there exist concerns that limit the wide…
The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…
Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…
The potential of large language models (LLMs) to mitigate the time- and cost- related challenges associated with inductive thematic analysis (ITA) has been extensively explored in the literature. However, the use of LLMs to support ITA has…
Large language models (LLMs) are emerging as promising tools for mental health care, offering scalable support through their ability to generate human-like responses. However, the effectiveness of these models in clinical settings remains…
Large Language Models (LLMs) have gained significant popularity for their impressive performance across diverse fields. However, LLMs are prone to hallucinate untruthful or nonsensical outputs that fail to meet user expectations in many…
Large Language Models (LLMs) gain substantial reasoning and decision-making capabilities from thought structures. However, existing methods such as Tree of Thought and Retrieval Augmented Thoughts often fall short in complex tasks due to…