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Large language models (LLMs) have shown impressive potential in helping with numerous medical challenges. Deploying LLMs in high-stakes applications such as medicine, however, brings in many concerns. One major area of concern relates to…

Computation and Language · Computer Science 2025-04-15 Hamed Fayyaz , Raphael Poulain , Rahmatollah Beheshti

The advent of large language models (LLMs) has facilitated the development of natural language text generation. It also poses unprecedented challenges, with content hallucination emerging as a significant concern. Existing solutions often…

Computation and Language · Computer Science 2024-06-06 Xiaoxi Sun , Jinpeng Li , Yan Zhong , Dongyan Zhao , Rui Yan

Hallucination, the generation of factually incorrect content, is a growing challenge in Large Language Models (LLMs). Existing detection and mitigation methods are often isolated and insufficient for domain-specific needs, lacking a…

Computation and Language · Computer Science 2025-01-22 Mengfei Liang , Archish Arun , Zekun Wu , Cristian Munoz , Jonathan Lutch , Emre Kazim , Adriano Koshiyama , Philip Treleaven

Evaluating large language models (LLMs) for clinical documentation tasks such as SOAP note generation remains challenging. Unlike standard summarization, these tasks require clinical abstraction, normalization of colloquial language, and…

Artificial Intelligence · Computer Science 2026-04-17 Bhavik Vachhani , Kush Shrisvastava , Pranshu Nema , Sai Chiranthan

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

The extraction of lung lesion information from clinical and medical imaging reports is crucial for research on and clinical care of lung-related diseases. Large language models (LLMs) can be effective at interpreting unstructured text in…

Computation and Language · Computer Science 2024-11-18 Diya Li , Asim Kadav , Aijing Gao , Rui Li , Richard Bourgon

With the rapid growth of large language models (LLMs) and vision-language models (VLMs) in medicine, simply integrating clinical text and medical imaging does not guarantee reliable reasoning. Existing multimodal models often produce…

Artificial Intelligence · Computer Science 2025-12-29 Zelin Zang , Wenyi Gu , Siqi Ma , Dan Yang , Yue Shen , Zhu Zhang , Guohui Fan , Wing-Kuen Ling , Fuji Yang

The development of Reasoning Large Language Models (RLLMs) has significantly improved multi-step reasoning capabilities, but it has also made hallucination problems more frequent and harder to eliminate. While existing approaches mitigate…

Computers and Society · Computer Science 2025-12-29 Haolang Lu , Yilian Liu , Jingxin Xu , Guoshun Nan , Yuanlong Yu , Zhican Chen , Kun Wang

Large language models (LLMs) have shown promise for generative and knowledge-intensive tasks including question-answering (QA) tasks. However, the practical deployment still faces challenges, notably the issue of "hallucination", where…

Computation and Language · Computer Science 2023-10-11 Ziwei Ji , Tiezheng Yu , Yan Xu , Nayeon Lee , Etsuko Ishii , Pascale Fung

Large language models (LLMs) have shown great potential in the medical domain. However, existing models still fall short when faced with complex medical diagnosis task in the real world. This is mainly because they lack sufficient reasoning…

Artificial Intelligence · Computer Science 2025-08-06 Qi Peng , Jialin Cui , Jiayuan Xie , Yi Cai , Qing Li

Large Language Models (LLMs) have fundamentally transformed approaches to Natural Language Processing (NLP) tasks across diverse domains. In healthcare, accurate and cost-efficient text classification is crucial, whether for clinical notes…

Computation and Language · Computer Science 2026-02-16 Hajar Sakai , Sarah S. Lam

Tabular data is often hidden in text, particularly in medical diagnostic reports. Traditional machine learning (ML) models designed to work with tabular data, cannot effectively process information in such form. On the other hand, large…

Machine Learning · Computer Science 2023-06-09 Aleksa Bisercic , Mladen Nikolic , Mihaela van der Schaar , Boris Delibasic , Pietro Lio , Andrija Petrovic

Leveraging outputs from multiple large language models (LLMs) is emerging as a method for harnessing their power across a wide range of tasks while mitigating their capacity for making errors, e.g., hallucinations. However, current…

Computation and Language · Computer Science 2025-08-05 Ming Pok Ng , Junqi Jiang , Gabriel Freedman , Antonio Rago , Francesca Toni

Large Language Models (LLMs) are trained on vast and diverse internet corpora that often include inaccurate or misleading content. Consequently, LLMs can generate misinformation, making robust fact-checking essential. This review…

As large language models continue to develop in the field of AI, text generation systems are susceptible to a worrisome phenomenon known as hallucination. In this study, we summarize recent compelling insights into hallucinations in LLMs.…

Computation and Language · Computer Science 2023-09-14 Hongbin Ye , Tong Liu , Aijia Zhang , Wei Hua , Weiqiang Jia

Large language models (LLMs) exhibit strong semantic understanding, yet struggle when user instructions involve ambiguous or conceptually misaligned terms. We propose the Language Graph Model (LGM) to enhance conceptual clarity by…

Computation and Language · Computer Science 2025-11-06 Wenchang Lei , Ping Zou , Yue Wang , Feng Sun , Lei Zhao

Existing LLM-based medical question-answering systems lack citation generation and evaluation capabilities, raising concerns about their adoption in practice. In this work, we introduce \name, the first end-to-end framework that facilitates…

Computation and Language · Computer Science 2025-06-10 Xiao Wang , Mengjue Tan , Qiao Jin , Guangzhi Xiong , Yu Hu , Aidong Zhang , Zhiyong Lu , Minjia Zhang

Large language models (LLMs) present a promising yet challenging frontier for automated source citation in scientific communication. Previous approaches to citation generation have been limited by citation ambiguity and LLM…

Computation and Language · Computer Science 2025-04-14 Yash Saxena , Deepa Tilwani , Ali Mohammadi , Edward Raff , Amit Sheth , Srinivasan Parthasarathy , Manas Gaur

Despite their impressive capabilities, large language models (LLMs) have been observed to generate responses that include inaccurate or fabricated information, a phenomenon commonly known as ``hallucination''. In this work, we propose a…

Computation and Language · Computer Science 2024-03-12 Yue Zhang , Leyang Cui , Wei Bi , Shuming Shi

Large Language Models (LLMs) and Large Reasoning Models (LRMs) offer transformative potential for high-stakes domains like finance and law, but their tendency to hallucinate, generating factually incorrect or unsupported content, poses a…

Artificial Intelligence · Computer Science 2026-01-16 Ahmad Pesaranghader , Erin Li