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Brain age gap estimation (BrainAGE) is a promising imaging-derived biomarker of neurobiological aging and disease risk, yet current approaches rely predominantly on T1-weighted structural MRI (T1w), overlooking functional vascular changes…

Image and Video Processing · Electrical Eng. & Systems 2025-12-10 Jordan Jomsky , Kay C. Igwe , Zongyu Li , Yiren Zhang , Max Lashley , Tal Nuriel , Andrew Laine , Jia Guo

Semantic segmentation in complex scenes relies not only on object appearance but also on object location and the surrounding environment. Nonetheless, it is difficult to model long-range context in the format of pairwise point correlations…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Xin Kang , Chaoqun Wang , Xuejin Chen

We propose a novel optimization framework to predict clinical severity from resting state fMRI (rs-fMRI) data. Our model consists of two coupled terms. The first term decomposes the correlation matrices into a sparse set of representative…

Neurons and Cognition · Quantitative Biology 2024-11-25 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart H. Mostofsky , Archana Venkataraman

Alzheimer Disease poses a significant challenge, necessitating early detection for effective intervention. MRI is a key neuroimaging tool due to its ease of use and cost effectiveness. This study analyzes machine learning methods for MRI…

Neurons and Cognition · Quantitative Biology 2024-08-12 Alwani Liyana Ahmad , Jose Sanchez-Bornot , Roberto C. Sotero , Damien Coyle , Zamzuri Idris , Ibrahima Faye

Functional magnetic resonance imaging (fMRI) functional connectivity between brain regions is often computed using parcellations defined by functional or structural atlases. Typically, some kind of voxel averaging is performed to obtain a…

In this study, we propose the use of persistent homology -- specifically Betti curves for brain age prediction and for distinguishing between healthy and pathological aging. The proposed framework is applied to 100 structural MRI scans from…

Neurons and Cognition · Quantitative Biology 2025-11-11 Debanjali Bhattacharya , Neelam Sinha

Mass spectrometry imaging (MSI) enables label-free visualization of molecular distributions across tissue samples but generates large and complex datasets that require effective peak picking to reduce data size while preserving meaningful…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Philipp Weigand , Nikolas Ebert , Shad A. Mohammed , Denis Abu Sammour , Carsten Hopf , Oliver Wasenmüller

Brain vessel segmentation of MR scans is a critical step in the diagnosis of cerebrovascular diseases. Due to the fine vessel structure, manual vessel segmentation is time consuming. Therefore, automatic deep learning (DL) based…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Omini Rathore , Richard Paul , Abigail Morrison , Hanno Scharr , Elisabeth Pfaehler

Accurately predicting early recurrence in brain tumor patients following surgical resection remains a clinical challenge. This study proposes a multi-modal machine learning framework that integrates structural MRI features with clinical…

Machine Learning · Computer Science 2025-09-03 Cheng Cheng , Zeping Chen , Rui Xie , Peiyao Zheng , Xavier Wang

Structural magnetic resonance imaging studies have shown that brain anatomical abnormalities are associated with cognitive deficits in preterm infants. Brain maturation and geometric features can be used with machine learning models for…

Machine Learning · Computer Science 2022-08-10 Zhiyuan Li , Hailong Li , Adebayo Braimah , Jonathan R. Dillman , Nehal A. Parikh , Lili He

Brain tumors remain a critical global health challenge, necessitating advancements in diagnostic techniques and treatment methodologies. A tumor or its recurrence often needs to be identified in imaging studies and differentiated from…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Shashidhar Reddy Javaji , Sovesh Mohapatra , Advait Gosai , Gottfried Schlaug

Early clinical assessment of Alzheimer's disease relies on behavior scores that measure a subject's language, memory, and cognitive skills. On the medical imaging side, functional magnetic resonance imaging has provided invaluable insights…

Signal Processing · Electrical Eng. & Systems 2026-04-14 Javier Salazar Cavazos , Maximillian Egan , Krisanne Litinas , Benjamin Hampstead , Scott Peltier

This study investigates fall risk prediction in older adults using various machine learning models trained on accelerometric, non-accelerometric, and combined data from 146 participants. Models combining both data types achieved superior…

Automatic speech emotion recognition (SER) by a computer is a critical component for more natural human-machine interaction. As in human-human interaction, the capability to perceive emotion correctly is essential to take further steps in a…

Sound · Computer Science 2022-10-27 Bagus Tris Atmaja , Masato Akagi

Predicting human trust in AI systems is crucial for safe integration of AI-based decision support tools, especially in healthcare. This study proposes a multi-modal machine learning framework that combines image and galvanic skin response…

Machine Learning · Computer Science 2025-12-05 Hamid Shamszare , Avishek Choudhury

Bone Age Assessment (BAA) is a widely used clinical technique that can accurately reflect an individual's growth and development level, as well as maturity. In recent years, although deep learning has advanced the field of bone age…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Qiong Lou , Han Yang , Fang Lu

A Brain Computer Interface (BCI) connects the human brain to the outside world, providing a direct communication channel. Electroencephalography (EEG) signals are commonly used in BCIs to reflect cognitive patterns related to motor function…

Machine Learning · Computer Science 2025-11-19 Abdullah Al Shiam , Md. Khademul Islam Molla , Abu Saleh Musa Miah , Md. Abdus Samad Kamal

Clinical decision-making agents can benefit from reusing prior decision experience. However, many memory-augmented methods store experiences as independent records without explicit relational structure, which may introduce noisy retrieval,…

Artificial Intelligence · Computer Science 2026-03-24 Xiao Han , Yuzheng Fan , Sendong Zhao , Haochun Wang , Bing Qin

We show that fMRI analysis using machine learning tools are sufficient to distinguish valence (i.e., positive or negative) of freely retrieved autobiographical memories in a cross-participant setting. Our methodology uses feature selection…

Machine Learning · Computer Science 2020-07-27 Alex Frid , Larry M. Manevitz , Norberto Eiji Nawa

Resting-state functional MRI (rs-fMRI) scans hold the potential to serve as a diagnostic or prognostic tool for a wide variety of conditions, such as autism, Alzheimer's disease, and stroke. While a growing number of studies have…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Meenakshi Khosla , Keith Jamison , Amy Kuceyeski , Mert Sabuncu