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Despite the notable success of deep neural networks (DNNs) in solving complex tasks, the training process still remains considerable challenges. A primary obstacle is the substantial time required for training, particularly as high…

Machine Learning · Computer Science 2025-09-09 Viet Hoang Pham , Hyo-Sung Ahn

Neural networks have long strived to emulate the learning capabilities of the human brain. While deep neural networks (DNNs) draw inspiration from the brain in neuron design, their training methods diverge from biological foundations.…

Neural and Evolutionary Computing · Computer Science 2026-02-24 Joseph Bingham , Saman Zonouz , Dvir Aran

Backpropagation is widely used to train artificial neural networks, but its relationship to synaptic plasticity in the brain is unknown. Some biological models of backpropagation rely on feedback projections that are symmetric with…

Neurons and Cognition · Quantitative Biology 2023-02-08 Navid Shervani-Tabar , Robert Rosenbaum

Backpropagation has long been criticized for being biologically implausible due to its reliance on concepts that are not viable in natural learning processes. Two core issues are the weight transport and update locking problems caused by…

Machine Learning · Computer Science 2026-01-14 Katharina Flügel , Daniel Coquelin , Marie Weiel , Charlotte Debus , Achim Streit , Markus Götz

Despite the widespread adoption of Backpropagation algorithm-based Deep Neural Networks, the biological infeasibility of the BP algorithm could potentially limit the evolution of new DNN models. To find a biologically plausible algorithm to…

Neural and Evolutionary Computing · Computer Science 2024-02-29 Jian-Hui Chen , Cheng-Lin Liu , Zuoren Wang

The backpropagation (BP) algorithm is often thought to be biologically implausible in the brain. One of the main reasons is that BP requires symmetric weight matrices in the feedforward and feedback pathways. To address this "weight…

Machine Learning · Computer Science 2018-12-24 Will Xiao , Honglin Chen , Qianli Liao , Tomaso Poggio

We propose a novel algorithm called Backpropagation Neural Tree (BNeuralT), which is a stochastic computational dendritic tree. BNeuralT takes random repeated inputs through its leaves and imposes dendritic nonlinearities through its…

Machine Learning · Computer Science 2024-04-30 Varun Ojha , Giuseppe Nicosia

In many scientific disciplines, we are interested in inferring the nonlinear dynamical system underlying a set of observed time series, a challenging task in the face of chaotic behavior and noise. Previous deep learning approaches toward…

Machine Learning · Computer Science 2022-07-07 Manuel Brenner , Florian Hess , Jonas M. Mikhaeil , Leonard Bereska , Zahra Monfared , Po-Chen Kuo , Daniel Durstewitz

One major criticism of deep learning centers around the biological implausibility of the credit assignment schema used for learning -- backpropagation of errors. This implausibility translates into practical limitations, spanning scientific…

Neural and Evolutionary Computing · Computer Science 2024-03-29 Alexander Ororbia , Ankur Mali , Adam Kohan , Beren Millidge , Tommaso Salvatori

The backpropagation algorithm, or backprop, is a widely utilized optimization technique in deep learning. While there's growing evidence suggesting that models trained with backprop can accurately explain neuronal data, no backprop-like…

Machine Learning · Computer Science 2024-05-28 Gananath R

The backpropagation algorithm has experienced remarkable success in training large-scale artificial neural networks; however, its biological plausibility has been strongly criticized, and it remains an open question whether the brain…

Neural and Evolutionary Computing · Computer Science 2026-03-27 Bariscan Bozkurt , Cengiz Pehlevan , Alper T Erdogan

How can we build agents that keep learning from experience, quickly and efficiently, after their initial training? Here we take inspiration from the main mechanism of learning in biological brains: synaptic plasticity, carefully tuned by…

Neural and Evolutionary Computing · Computer Science 2018-08-01 Thomas Miconi , Jeff Clune , Kenneth O. Stanley

Animal behaviour depends on learning to associate sensory stimuli with the desired motor command. Understanding how the brain orchestrates the necessary synaptic modifications across different brain areas has remained a longstanding puzzle.…

Neurons and Cognition · Quantitative Biology 2018-01-03 João Sacramento , Rui Ponte Costa , Yoshua Bengio , Walter Senn

Deep learning has redefined the field of artificial intelligence (AI) thanks to the rise of artificial neural networks, which are architectures inspired by their neurological counterpart in the brain. Through the years, this dualism between…

Machine Learning · Computer Science 2023-02-21 Tommaso Salvatori , Yuhang Song , Thomas Lukasiewicz , Rafal Bogacz , Zhenghua Xu

Spiking neural networks (SNN) are delivering energy-efficient, massively parallel, and low-latency solutions to AI problems, facilitated by the emerging neuromorphic chips. To harness these computational benefits, SNN need to be trained by…

Neural and Evolutionary Computing · Computer Science 2021-10-28 Guangzhi Tang , Neelesh Kumar , Ioannis Polykretis , Konstantinos P. Michmizos

Researchers have proposed that deep learning, which is providing important progress in a wide range of high complexity tasks, might inspire new insights into learning in the brain. However, the methods used for deep learning by artificial…

Neural and Evolutionary Computing · Computer Science 2019-07-03 Isabella Pozzi , Sander Bohté , Pieter Roelfsema

Interest in biologically inspired alternatives to backpropagation is driven by the desire to both advance connections between deep learning and neuroscience and address backpropagation's shortcomings on tasks such as online, continual…

Neural and Evolutionary Computing · Computer Science 2020-06-18 Jack Lindsey , Ashok Litwin-Kumar

Finding biologically plausible alternatives to back-propagation of errors is a fundamentally important challenge in artificial neural network research. In this paper, we propose a learning algorithm called error-driven Local Representation…

Neural and Evolutionary Computing · Computer Science 2018-11-19 Alexander G. Ororbia , Ankur Mali

Empowered by the backpropagation (BP) algorithm, deep neural networks have dominated the race in solving various cognitive tasks. The restricted training pattern in the standard BP requires end-to-end error propagation, causing large memory…

Machine Learning · Computer Science 2022-05-17 Wenzhe Guo , Mohammed E Fouda , Ahmed M. Eltawil , Khaled N. Salama

Over the last four decades, the amazing success of deep learning has been driven by the use of Stochastic Gradient Descent (SGD) as the main optimization technique. The default implementation for the computation of the gradient for SGD is…

Neural and Evolutionary Computing · Computer Science 2024-12-31 Qianli Liao , Liu Ziyin , Yulu Gan , Brian Cheung , Mark Harnett , Tomaso Poggio