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Alzheimer's disease (AD) is the most common neurodegenerative disease in older people. Despite considerable efforts to find a cure for AD, there is a 99.6% failure rate of clinical trials for AD drugs, likely because AD patients cannot…

Machine Learning · Computer Science 2019-03-25 Jack Albright

Autism spectrum disorder (ASD) is a highly disabling mental disease that brings significant impairments of social interaction ability to the patients, making early screening and intervention of ASD critical. With the development of the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Ruimin Ma , Ruitao Xie , Yanlin Wang , Jintao Meng , Yanjie Wei , Wenhui Xi , Yi Pan

Every day, poison control centers (PCC) are called for immediate classification and treatment recommendations if an acute intoxication is suspected. Due to the time-sensitive nature of these cases, doctors are required to propose a correct…

By 2040, age-related macular degeneration (AMD) will affect approximately 288 million people worldwide. Identifying individuals at high risk of progression to late AMD, the sight-threatening stage, is critical for clinical actions,…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Yifan Peng , Tiarnan D. Keenan , Qingyu Chen , Elvira Agrón , Alexis Allot , Wai T. Wong , Emily Y. Chew , Zhiyong Lu

Autism Spectrum Disorder (ASD) is a severe neuropsychiatric disorder that affects intellectual development, social behavior, and facial features, and the number of cases is still significantly increasing. Due to the variety of symptoms ASD…

Image and Video Processing · Electrical Eng. & Systems 2021-10-11 Ryan Liu , Spencer He

Alzheimer's Disease (AD) ravages the cognitive ability of more than 5 million Americans and creates an enormous strain on the health care system. This paper proposes a machine learning predictive model for AD development without medical…

Quantitative Methods · Quantitative Biology 2020-06-17 Courtney Cochrane , David Castineira , Nisreen Shiban , Pavlos Protopapas

Objective. Type 2 diabetes mellitus (T2DM) is a highly prevalent non-communicable chronic disease that substantially reduces life expectancy. Accurate estimation of all-cause mortality risk in T2DM patients is crucial for personalizing and…

Importance: The prevalence of severe mental illnesses (SMIs) in the United States is approximately 3% of the whole population. The ability to conduct risk screening of SMIs at large scale could inform early prevention and treatment.…

Artificial Intelligence · Computer Science 2023-01-13 Dianbo Liu , Karmel W. Choi , Paulo Lizano , William Yuan , Kun-Hsing Yu , Jordan W. Smoller , Isaac Kohane

Suicide remains a public health challenge, necessitating improved detection methods to facilitate timely intervention and treatment. This systematic review evaluates the role of Artificial Intelligence (AI) and Machine Learning (ML) in…

Audio and Speech Processing · Electrical Eng. & Systems 2025-10-29 Ambre Marie , Marine Garnier , Thomas Bertin , Laura Machart , Guillaume Dardenne , Gwenolé Quellec , Sofian Berrouiguet

Type 2 Diabetes is one of the most major and fatal diseases known to human beings, where thousands of people are subjected to the onset of Type 2 Diabetes every year. However, the diagnosis and prevention of Type 2 Diabetes are relatively…

Depression has been the leading cause of mental-health illness worldwide. Major depressive disorder (MDD), is a common mental health disorder that affects both psychologically as well as physically which could lead to loss of lives. Due to…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Anupama Ray , Siddharth Kumar , Rutvik Reddy , Prerana Mukherjee , Ritu Garg

Chronic diseases are long-term, manageable, yet typically incurable conditions, highlighting the need for effective preventive strategies. Machine learning has been widely used to assess individual risk for chronic diseases. However, many…

Machine Learning · Computer Science 2025-06-24 Minh Le , Khoi Ton

Diabetes has emerged as a significant global health issue, especially with the increasing number of cases in many countries. This trend Underlines the need for a greater emphasis on early detection and proactive management to avert or…

Machine Learning · Computer Science 2025-06-16 Mowafaq Salem Alzboon , Muhyeeddin Alqaraleh , Mohammad Subhi Al-Batah

Childhood and adolescent obesity rates are a global concern because obesity is associated with chronic diseases and long-term health risks. Artificial intelligence technology has emerged as a promising solution to accurately predict obesity…

Artificial Intelligence · Computer Science 2023-09-01 Ji-Hoon Jeong , In-Gyu Lee , Sung-Kyung Kim , Tae-Eui Kam , Seong-Whan Lee , Euijong Lee

Machine learning algorithms can sometimes exacerbate health disparities based on ethnicity, gender, and other factors. There has been limited work at exploring potential biases within algorithms deployed on a small scale, and/or within…

Computational Engineering, Finance, and Science · Computer Science 2023-07-07 Abhay Goyal , Nimay Parekh , Lam Yin Cheung , Koustuv Saha , Frederick L Altice , Robin O'hanlon , Roger Ho Chun Man , Christian Poellabauer , Honoria Guarino , Pedro Mateu Gelabert , Navin Kumar

Cardiovascular disease and chronic kidney disease are major complications of diabetes, leading to high morbidity and mortality. Early detection of these conditions is critical, yet traditional diagnostic markers often lack sensitivity in…

Other Quantitative Biology · Quantitative Biology 2025-10-20 Syed Ibad Hasnain

The accuracy of coronary artery disease (CAD) diagnosis is dependent on a variety of factors, including demographic, symptom, and medical examination, ECG, and echocardiography data, among others. In this context, artificial intelligence…

Artificial Intelligence · Computer Science 2023-08-30 Elham Nasarian , Danial Sharifrazi , Saman Mohsenirad , Kwok Tsui , Roohallah Alizadehsani

Bayesian response adaptive clinical trials are currently evaluating experimental therapies for several diseases. Adaptive decisions, such as pre-planned variations of the randomization probabilities, attempt to accelerate the development of…

Methodology · Statistics 2021-05-25 Marta Bonsaglio , Sandra Fortini , Steffen Ventz , Lorenzo Trippa

The drug overdose crisis in the United States continues to intensify. Fatalities have increased five-fold since 1999 reaching a record high of 108,000 deaths in 2021. The epidemic has unfolded through distinct waves of different drug types,…

Applications · Statistics 2023-09-27 Lucas Böttcher , Tom Chou , Maria R. D'Orsogna

Prediction of disease onset from patient survey and lifestyle data is quickly becoming an important tool for diagnosing a disease before it progresses. In this study, data from the National Health and Nutrition Examination Survey (NHANES)…

Machine Learning · Statistics 2017-08-25 John Semerdjian , Spencer Frank