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Advances in medical imaging technologies have enabled the collection of longitudinal images, which involve repeated scanning of the same patients over time, to monitor disease progression. However, predictive modeling of such data remains…

Image and Video Processing · Electrical Eng. & Systems 2025-04-25 Chen Liu , Ke Xu , Liangbo L. Shen , Guillaume Huguet , Zilong Wang , Alexander Tong , Danilo Bzdok , Jay Stewart , Jay C. Wang , Lucian V. Del Priore , Smita Krishnaswamy

Brain Magnetic Resonance Imaging (MRI) plays a central role in studying neurological development, aging, and diseases. One key application is Brain Age Prediction (BAP), which estimates an individual's biological brain age from MRI data.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Danilo Danese , Angela Lombardi , Matteo Attimonelli , Giuseppe Fasano , Tommaso Di Noia

Segmenting a structural magnetic resonance imaging (MRI) scan is an important pre-processing step for analytic procedures and subsequent inferences about longitudinal tissue changes. Manual segmentation defines the current gold standard in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Alex Fedorov , Jeremy Johnson , Eswar Damaraju , Alexei Ozerin , Vince Calhoun , Sergey Plis

Over the years, Machine Learning models have been successfully employed on neuroimaging data for accurately predicting brain age. Deviations from the healthy brain aging pattern are associated to the accelerated brain aging and brain…

Image and Video Processing · Electrical Eng. & Systems 2023-06-23 M. Tanveer , M. A. Ganaie , Iman Beheshti , Tripti Goel , Nehal Ahmad , Kuan-Ting Lai , Kaizhu Huang , Yu-Dong Zhang , Javier Del Ser , Chin-Teng Lin

We present DataFlow, a computational framework for building, testing, and deploying high-performance machine learning systems on unbounded time-series data. Traditional data science workflows assume finite datasets and require substantial…

Machine Learning · Computer Science 2026-01-01 Giacinto Paolo Saggese , Paul Smith

Predicting long-term bone remodeling after mandibular reconstruction would be of great clinical benefit, yet standard generative models struggle to maintain trajectory-level consistency and anatomical fidelity over long horizons. We…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Hamidreza Aftabi , Faye Yu , Brooke Switzer , Zachary Fishman , Eitan Prisman , Antony Hodgson , Cari Whyne , Sidney Fels , Michael Hardisty

Neuroimaging-based prediction methods for intelligence and cognitive abilities have seen a rapid development in literature. Among different neuroimaging modalities, prediction based on functional connectivity (FC) has shown great promise.…

Neurons and Cognition · Quantitative Biology 2023-07-20 Yang Li , Xin Ma , Raj Sunderraman , Shihao Ji , Suprateek Kundu

Quantitative susceptibility mapping (QSM) has been increasingly applied in longitudinal studies of neurodegenerative diseases and aging to assess temporal alterations in brain iron and myelin. The accuracy of such investigations depends on…

Quantitative Methods · Quantitative Biology 2026-05-05 Jiye Kim , Hwihun Jeong , Taechang Kim , Eunseon Jeong , Jinhee Jang , Yangsean Choi , Jongho Lee

Generating high-quality time-series data is challenging because real-world signals often exhibit multimodal patterns and multiscale dynamics, including oscillations and high-frequency variations. Flow Matching (FM) offers an efficient…

Machine Learning · Computer Science 2026-05-29 Junru Zhang , Lang Feng , Jinbo Wang , Xu Guo , Yucheng Wang , Han Yu , Min Wu , Yabo Dong , Duanqing Xu

This paper presents a novel approach, termed {\em Temporal Latent Residual Network (TLRN)}, to predict a sequence of deformation fields in time-series image registration. The challenge of registering time-series images often lies in the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Nian Wu , Jiarui Xing , Miaomiao Zhang

Magnetic Resonance Imaging (MRI) of the fetal brain has become a key tool for studying brain development in vivo. Yet, its assessment remains challenging due to variability in brain maturation, imaging protocols, and uncertain estimates of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Johannes Tischer , Patric Kienast , Marlene Stümpflen , Gregor Kasprian , Georg Langs , Roxane Licandro

Glioblastoma exhibits diverse, infiltrative, and patient-specific growth patterns that are only partially visible on routine MRI, making it difficult to reliably assess true tumor extent and personalize treatment planning and follow-up. We…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Valentin Biller , Niklas Bubeck , Lucas Zimmer , Ayhan Can Erdur , Sandeep Nagar , Anke Meyer-Baese , Daniel Rückert , Benedikt Wiestler , Jonas Weidner

Although obtaining deep brain activity from non-invasive scalp electroencephalography (sEEG) is crucial for neuroscience and clinical diagnosis, directly generating high-fidelity intracranial electroencephalography (iEEG) signals remains a…

Neurons and Cognition · Quantitative Biology 2026-05-26 Dongyi He , Bin Jiang , Kecheng Feng , Luyin Zhang , Ling Liu , Yuxuan Li , Yun Zhao , He Yan

Simulating aging in 3D brain MRI scans can reveal disease progression patterns in neurological disorders such as Alzheimer's disease. Current deep learning-based generative models typically approach this problem by predicting future scans…

Image and Video Processing · Electrical Eng. & Systems 2025-08-28 Jaivardhan Kapoor , Jakob H. Macke , Christian F. Baumgartner

Functional magnetic resonance imaging (fMRI) time series are known to exhibit long-range temporal dependencies that challenge traditional modeling approaches. In this study, we propose a novel computational pipeline to characterize and…

Applications · Statistics 2025-08-19 Yasaman Shahhosseini , Cédric Beaulac , Farouk S. Nathoo , Michelle F. Miranda

Changes over time in brain anatomy can provide important insight for treatment design or scientific analyses. We present a method that predicts how a brain MRI for an individual will change over time. We model changes using a diffeomorphic…

Computer Vision and Pattern Recognition · Computer Science 2020-06-02 Marianne Rakic , John Guttag , Adrian V. Dalca

Generating high-quality time series data has emerged as a critical research topic due to its broad utility in supporting downstream time series mining tasks. A major challenge lies in modeling the intrinsic stochasticity of temporal…

Artificial Intelligence · Computer Science 2025-11-20 He Panjing , Cheng Mingyue , Li Li , Zhang XiaoHan

Deformable image registration plays a fundamental role in medical image analysis by enabling spatial alignment of anatomical structures across subjects. While recent deep learning-based approaches have significantly improved computational…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jiaqi Shang , Haojin Wu , Yinyi Lai , Zongyu Li , Chenghao Zhang , Jia Guo

Deep learning (DL) models for segmenting various anatomical structures have achieved great success via a static DL model that is trained in a single source domain. Yet, the static DL model is likely to perform poorly in a continually…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Xiaofeng Liu , Helen A. Shih , Fangxu Xing , Emiliano Santarnecchi , Georges El Fakhri , Jonghye Woo

Understanding distinct neurological aging patterns across various populations is vital in the context of a globally aging populace. This study seeks to unravel the structural variations in the aging brain, taking into consideration…

Neurons and Cognition · Quantitative Biology 2024-08-15 Alphin J Thottupattu , Jayanthi Sivaswamy , Bharath Holla , Jithender Saini