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In recent years, it has been well-established that adding a restart mechanism can alter the firstpassage statistics of a stochastic processes in useful and interesting ways. Though different mecha-nisms have been investigated, we derive a…

Probability · Mathematics 2021-09-09 Jason M. Flynn , Sergei S. Pilyugin

Hydrogen embrittlement in metals is strongly governed by hydrogen diffusion and trapping, yet predicting these effects in polycrystalline systems remains challenging. This work introduces a multiscale modeling framework that links atomistic…

Materials Science · Physics 2026-01-12 Bhanuj Jain , Alaa Olleak , Junyan He , Adarsh Chaurasia , Davide Di Stefano

Biological molecular machines convert free energy between different forms in cells, often at high efficiency. Optimal control theory provides a framework to elucidate design principles governing energetically efficient driving. Here, we use…

Biological Physics · Physics 2025-06-12 W. Callum Wareham , David A. Sivak

We study the statistics of the first passage of a random walker to absorbing subsets of the boundary of compact domains in different spatial dimensions. We describe a novel diagnostic method to quantify the trajectory-to-trajectory…

Statistical Mechanics · Physics 2013-05-06 T. G. Mattos , C. Mejía-Monasterio , R. Metzler , G. Oshanin , G. Schehr

We study analytically the dynamics and the micro-structural changes of a host medium caused by a driven tracer particle moving in a confined, quiescent molecular crowding environment. Imitating typical settings of active micro-rheology…

Statistical Mechanics · Physics 2016-03-17 O. Bénichou , P. Illien , G. Oshanin , A. Sarracino , R. Voituriez

We consider an isolated gaseous system, divided in two parts by an adiabatic movable frictionless internal wall undergoing Brownian motion. We show how this kind of motion can lead to a substantial decrease of the system entropy. This…

Classical Physics · Physics 2007-05-23 B. Crosignani , P. Di Porto

Several important biological processes are initiated by the binding of a protein to a specific site on the DNA. The strategy adopted by a protein, called transcription factor (TF), for searching its specific binding site on the DNA has been…

Biological Physics · Physics 2018-10-17 Soumendu Ghosh , Bhavya Mishra , Anatoly B. Kolomeisky , Debashish Chowdhury

We consider the escape of a flexible, self-avoiding polymer chain out of a confined geometry. By means of simulations, we demonstrate that the translocation time can be described by a simple scaling law that exhibits a nonlinear dependence…

Soft Condensed Matter · Physics 2009-11-11 Angelo Cacciuto , Erik Luijten

We show that transport in the presence of entropic barriers exhibits peculiar characteristics which makes it distinctly different from that occurring through energy barriers. The constrained dynamics yields a scaling regime for the particle…

Statistical Mechanics · Physics 2009-11-11 D. Reguera , G. Schmid , P. S. Burada , J. M. Rubí , P. Hänggi

As a first step in the first passage problem for passive tracer in stratified porous media, we consider the case of a two-dimensional system consisting of two layers with different convection velocities. Using a lattice generating function…

Condensed Matter · Physics 2009-10-22 Jysoo Lee , Joel Koplik

Under some weak conditions, the first-passage time of the Brownian motion to a continuous curved boundary is an almost surely finite stopping time. Its probability density function (pdf) is explicitly known only in few particular cases.…

Probability · Mathematics 2016-01-22 Samuel Herrmann , Etienne Tanré

Brownian motion is a central scientific paradigm. Recently, due to increasing efforts and interests towards miniaturization and small-scale physics or biology, the effects of confinement on such a motion have become a key topic of…

Statistical Mechanics · Physics 2023-03-13 Elodie Millan , Maxime Lavaud , Yacine Amarouchene , Thomas Salez

Polymers confined in corrugated channels, i.e. channels of varying amplitude, display {multiple local maxima and minima of the diffusion coefficient upon increasing their degree of polymerization $N$}. We propose a theoretical effective…

Soft Condensed Matter · Physics 2023-08-28 Emanuele Locatelli , Valentino Bianco , Chantal Valeriani , Paolo Malgaretti

In this paper we consider the dynamics of harmonically-confined atomic gases. We present various general results which are independent of particle statistics, interatomic interactions and dimensionality. Of particular interest is the…

Quantum Gases · Physics 2014-03-13 Z. Wu , E. Zaremba

Given a survival distribution on the positive half-axis and a Brownian motion, a solution of the inverse first-passage problem consists of a boundary so that the first passage time over the boundary has the given distribution. We show that…

Probability · Mathematics 2015-09-01 Erik Ekström , Svante Janson

We study the transport of Brownian particles through a corrugated channel caused by a force field containing curl-free (scalar potential) and divergence-free (vector potential) parts. We develop a generalized Fick-Jacobs approach leading to…

Statistical Mechanics · Physics 2013-01-03 S. Martens , A. V. Straube , G. Schmid , L. Schimansky-Geier , P. Hänggi

Fractional Brownian motion (FBM), a non-Markovian self-similar Gaussian stochastic process with long-ranged correlations, represents a widely applied, paradigmatic mathematical model of anomalous diffusion. We report the results of…

The conductance of a molecular junction is commonly determined by either charge-transfer-doping, where alignment of the Fermi energy to the molecular levels is achieved, or tunnelling through the tails of molecular resonances within the…

Mesoscale and Nanoscale Physics · Physics 2016-08-31 R. Gutierrez , G. Fagas , K. Richter , F. Grossmann , R. Schmidt

We study dynamical properties of confined, self-propelled Brownian particles in an inhomogeneous activity profile. Using Brownian dynamics simulations, we calculate the probability to reach a fixed target and the mean first passage time to…

Soft Condensed Matter · Physics 2019-08-30 Hidde Vuijk , Abhinav Sharma , Debasish Mondal , Jens-Uwe Sommer , Holger Merlitz

In this note, we demonstrated for the first time that one can derive an expression for the effective diffusion coefficient, equal to the Lifson-Jackson formula, using a subsequent homogenization of the 1D reaction-diffusion-advection…

Chemical Physics · Physics 2016-08-03 Steffen Martens