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The numerical tools to simulate the bidomain model in cardiac electrophysiology are constantly developing due to the great clinical interest and scientific advances in mathematical models and computational power. The bidomain model consists…

Numerical Analysis · Mathematics 2025-11-03 Gopika P B , Peter Bastian , Nagaiah Chamakuri

We present a flexible scalable open-source computational framework, named SECUReFoam, based on the finite-volume library OpenFOAM(R), for flow and transport problems in highly heterogeneous geological media and other porous materials. The…

Numerical Analysis · Mathematics 2022-12-22 Matteo Icardi , Eugenio Pescimoro , Federico Municchi , Juan H Hidalgo

GeoChemFoam is an open-source OpenFOAM-based numerical modelling toolbox that includes a range of custom packages to solve complex flow processes including multiphase transport with interface transfer, single-phase flow in multiscale porous…

Fluid Dynamics · Physics 2021-10-08 Julien Maes , Hannah P. Menke

Echocardiography (ECHO) video is widely used for cardiac examination. In clinical, this procedure heavily relies on operator experience, which needs years of training and maybe the assistance of deep learning-based systems for enhanced…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Xinrui Zhou , Yuhao Huang , Wufeng Xue , Haoran Dou , Jun Cheng , Han Zhou , Dong Ni

In computational modelling of coronary haemodynamics, imposing patient-specific flow conditions is paramount, yet often impractical due to resource and time constraints, limiting the ability to perform a large number of simulations…

Medical Physics · Physics 2025-03-03 Mingzi Zhang , Hamed Keramati , Ramtin Gharleghi , Susann Beier

Deviation of blood flow from an optimal range is known to be associated with the initiation and progression of vascular pathologies. Important open questions remain about how the abnormal flow drives specific wall changes in pathologies…

Human blood flow is a multi-scale problem: in first approximation, blood is a dense suspension of plasma and deformable red cells. Physiological vessel diameters range from about one to thousands of cell radii. Current computational models…

Soft Condensed Matter · Physics 2015-03-17 Florian Janoschek , Federico Toschi , Jens Harting

The extraordinary aerial agility of hummingbirds and insects continues to inspire the design of flapping-wing drones. To replicate and analyze such flight, computational fluid dynamics (CFD) simulations that couple flow solvers with rigid…

Large parameter studies of fluid dynamic instabilities can crucially be simplified, if the user does not need to specify the simulation time. For this purpose, a steady state detection is implemented in the CFD library OpenFOAM. It…

Fluid Dynamics · Physics 2017-09-12 Martin Boesler , Norbert Weber

This work presents a biventricular electromechanical human heart model that is comprehensive and clinically relevant, integrating a realistic 3D heart geometry with both systemic and pulmonary hemodynamics. The model uses a two-way…

Medical Physics · Physics 2025-09-05 Milad Hasani , Alireza Rezania , Sam Riahi

OpenCAEPoro is a parallel numerical simulation software developed in C++ for simulating multiphase and multicomponent flows in porous media. The software utilizes a set of general-purpose compositional model equations, enabling it to handle…

Mathematical Software · Computer Science 2024-06-18 Shizhe Li , Chen-Song Zhang

Computational models are increasingly used for diagnosis and treatment of cardiovascular disease. To provide a quantitative hemodynamic understanding that can be effectively used in the clinic, it is crucial to quantify the variability in…

Computational Engineering, Finance, and Science · Computer Science 2021-02-02 Xue Li , Daniele E. Schiavazzi

Advancing human induced pluripotent stem cell derived cardiomyocyte (hiPSC-CM) technology will lead to significant progress ranging from disease modeling, to drug discovery, to regenerative tissue engineering. Yet, alongside these potential…

We present the molecular hyperdynamics algorithm and its implementation to the nonorthogonal tight-binding model NTBM and the corresponding software. Due to its multiscale structure, the proposed approach provides the long time scale…

We are interested in simulating blood flow in arteries with variable elasticity with a one dimensional model. We present a well-balanced finite volume scheme based on the recent developments in shallow water equations context. We thus get a…

Numerical Analysis · Mathematics 2012-04-10 Olivier Delestre , Pierre-Yves Lagrée

Boundary condition tuning is a fundamental step in patient-specific cardiovascular modeling. Despite an increase in offline training cost, recent methods in data-driven variational inference can efficiently estimate the joint posterior…

Machine Learning · Computer Science 2026-03-23 Chloe H. Choi , Alison L. Marsden , Daniele E. Schiavazzi

Computational fluid dynamics (CFD) in combination with patient-specific medical images has been used to correlate flow phenotypes with disease initiation, progression and outcome, in search of a prospective clinical tool. A large number of…

Fluid Dynamics · Physics 2023-05-26 Henrik A. Kjeldsberg , Joakim Sundnes , Kristian Valen-Sendstad

Analysing the haemodynamics of flow in carotid artery disease serves as a means to better understand the development and progression of associated complex diseases. Carotid artery disease can predispose people to major adverse…

The analysis of the Reynolds Stress Transport Equation (RSTE) provides fundamental physical insights that are essential for the development and validation of advanced turbulence models. However, a comprehensive and validated tool for…

Fluid Dynamics · Physics 2025-11-07 Mario J. Rincón , Christoffer Hansen , Martino Reclari , Mahdi Abkar

Numerical predictions of blood flow and hemodynamic properties through a stenotic and aneurysmal rigid artery are studied in the presence of blood clot at constricted area. Finite element method has been used to solve the steady partial…

Fluid Dynamics · Physics 2020-05-20 Mohammed Nasir Uddin , M. Monir Uddin , Md. Monjarul Alam
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